Gene/Proteome Database (LMPD)

LMPD ID
LMP008925
Gene ID
39393
Species
Drosophila melanogaster (Drosophila)
Gene Name
Esterase P
Gene Symbol
Est-P
Synonyms
CG17148; Dmel\CG17148; Est-5; EST-5; Est-7; est-P; Est7; EST7; EstP; ESTP; psiEst-6; PsiEst-6; yEst-6; yEst6
Alternate Names
CG17148-PA; Est-P-PA; esterase P
Chromosome
3L
Map Location
69A1-69A1
EC Number
3.1.1.1

Proteins

esterase P
Refseq ID NP_788501
Protein GI 28574501
UniProt ID P18167
mRNA ID NM_176323
Length 544
RefSeq Status REVIEWED
MSIFKRLLCLTLLWIAALESEADPLIVEITNGKIRGKDNGLYYSYESIPNAEHPTGALRFEAPQPYSHHWTDVFNATQSPVECMQWNQFINENNKLMGDEDCLTVSIYKPKKPNRSSFPVVVLLHGGAFMFGSGSIYGHDSIMREGTLLVVKISFGLGPLGFASTGDRHLPGNYGLKDQRLALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPWVIQQGGRRRAFELGRIVGCGHTNVSAELKDCLKSKPASDIVSAVRSFLVFSYVPFSAFGPVVEPSDAPDAFLTEDPRAVIKSGKFAQVPWAVTYTTEDGGYNAAQLLERNKLTGESWIDLLNDRWFDWAPYLLFYRDAKKTIKDMDDLSFDLRQQYLADRRFSVESYWNVQRMFTDVLFKNSVPSAIDLHRKYGKSPVYSFVYDNPTDSGVGQLLSNRTDVHFGTVHGDDFFLIFNTAAYRTGIRPDEEVISKKFIGMLEDFALNDKGTLTFGECNFQNNVNSKEYQVLRISRNACKNEEYARFP

Gene Information

Entrez Gene ID
39393
Gene Name
Esterase P
Gene Symbol
Est-P
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005576 IEA:UniProtKB-KW C extracellular region
GO:0052689 IDA:FlyBase F carboxylic ester hydrolase activity
GO:0008152 IDA:GOC P metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
dme00983 Drug metabolism - other enzymes
ko00983 Drug metabolism - other enzymes
dme01100 Metabolic pathways

Domain Information

InterPro Annotations

Accession Description
IPR029058 Alpha/Beta hydrolase fold
IPR019826 Carboxylesterase type B, active site
IPR019819 Carboxylesterase type B, conserved site
IPR002018 Carboxylesterase, type B

UniProt Annotations

Entry Information

Gene Name
Esterase P
Protein Entry
ESTP_DROME
UniProt ID
P18167
Species
Drosophila

Comments

Comment Type Description
Catalytic Activity A carboxylic ester + H(2)O = an alcohol + a carboxylate. {ECO:0000255|PROSITE-ProRule:PRU10039}.
Developmental Stage Mainly in late larvae.
Similarity Belongs to the type-B carboxylesterase/lipase family. {ECO:0000305}.
Subcellular Location Secreted.
Subunit Monomer.

Identical and Related Proteins

Unique RefSeq proteins for LMP008925 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
28574501 RefSeq NP_788501 544 esterase P

Identical Sequences to LMP008925 proteins

Reference Database Accession Length Protein Name
GI:28574501 GenBank ABB36447.1 544 LP12708p [Drosophila melanogaster]
GI:28574501 GenBank ACL88585.1 544 Est-P-PA, partial [synthetic construct]
GI:28574501 gnl FlyBase 544 esterase P [Drosophila melanogaster]
GI:28574501 SwissProt P18167.2 544 RecName: Full=Esterase P; Short=Est-P; AltName: Full=Carboxylic-ester hydrolase P; Short=Carboxylesterase-P; Flags: Precursor [Drosophila melanogaster]

Related Sequences to LMP008925 proteins

Reference Database Accession Length Protein Name
GI:28574501 GenBank AAA28520.1 544 carboxylesterase P [Drosophila melanogaster]
GI:28574501 GenBank AAU05616.1 544 yEst-6 [Drosophila simulans]
GI:28574501 GenBank AAU05618.1 544 yEst-6 [Drosophila sechellia]
GI:28574501 GenBank EDW41232.1 544 esterase P [Drosophila sechellia]
GI:28574501 GenBank AHL54353.1 544 Sequence 9 from patent US 8642273
GI:28574501 RefSeq XP_002030246.1 544 esterase P [Drosophila sechellia]