Gene/Proteome Database (LMPD)

LMPD ID
LMP008951
Gene ID
40201
Species
Drosophila melanogaster (Drosophila)
Gene Name
gigas
Gene Symbol
gig
Synonyms
6975; C1; CG6975; Dmel\CG6975; dTsc2; dTSC2; Gigas; gig|Tsc2; l(3)109; ME 109; tsc2; Tsc2; TSC2; Tsc2/gig
Chromosome
3L
Map Location
76F2-76F2

Proteins

gigas, isoform A
Refseq ID NP_524177
Protein GI 17737673
UniProt ID Q9VW83
mRNA ID NM_079453
Length 1847
RefSeq Status REVIEWED
MNSKDKSKFKLFLKSLPAGYVGERTLRPEFERELRPEQPVAQRCRMLKELGDTQLHNFNLDESAITILFNLTNDLIVPNKPAETRQIALSFYKRLIHTQYKNLTIMREKFFLVIQNHEAREDLRHLLELLDTLTDNGKDITNFEEKIGKFMLLWIPAITEANLLTPYLDILVNLIKFNAAHLDKDILVGIVQNACDLSCSVTVNEIGLQCLTILEMVIGYTIFPSEPLPQCITTLCRTVNHAPYCPSSFKIMKNLLGTQLGYHSMKMMCSILNDRALYDDAHLLRGAVFHLNMNIFGSNIIFQVSPMTYATNVLTAFLRALDSRQVIVTFEVILSVRMVITKRQLSEIIWDLICDIMSSIVSNIEYYEEVNINKDRLHHLQINFHENIDCIEKLLQQDRSQILGNVERIYDLIERVADRRPEASVLALIEYRSRRVTATRPDWLQVLAQFVRRYYRMSNVNVRIKTIEALVQIMDQNRACYEEEILSRVVLVHLSHIHLESSVQVRVAVARALSNFATHCDTKRCMDLLDILEALINRPFEHTRHGSSSGEGTLAEVTFGLVNNESEISDIIAAVDGLVKVFAIKLHRLPGIHALKIFNILMDHLELHYERPKIFEHISVVRYKIFAWLLKARANGSYHIGYPEGSTEVVKFSPYLGIDSPLLPQAHPTAISIRRVCKLIVRCLEHDTDYQVFQLVIRELPKVLQNKALVQGNDIEELANTLLKINLVSNNKFKRPTDEFHALVLPAIASLVIYHESLQPQQHYGIITALNSRVLTGIASVCINTMTILILEMPEALMRKLPDVLLQMSKMSDTNALATPVLEFLSLLIHLSKHLFANFTSMHNMYVFAITLPYTKPHRYDHYTVSLAHHVIAGWFLKCKLELRRNCVNYIKSSIQSNAKMLSSDIVNLNSLNEDSSNRKRSTSLTERGSRNNANAWNDLEMRPQMNNGLRNFHAELAETCFDFLARHTYSPCPSMPKRLPAAEFLLKDGVSQTWLVGNNLVTITTSGCPSAPARSGLCERCAQLGKAPSISLNSKSLSDAAPPLSPERERRYTKVSLQHSSGNESAGSTELTSSSSSNSAAAGGHPHRQISNSSTASLDALSRRGSNPEALGSALGEGAHTGSNTSLLGNSLSQSSVSMSPSSGSVVQQPVCVRACTGWAEVLVRRPTGNVSWITRIQNPITNDCFGQELPFNNVVSLFLPTAHGGVFGPDNTIQAPPHTLADPEPEPEAEVNAATAPQASALRSRMVAKARALQRQEEIHSVGGNGNGNGNGNGSGNAPSTGGAAAIPIPRVPASGKRGKEAALCGSVSDGEADDDSLAFEDAQSRARNPVRRVNSSPEMSSSWRQSFLTNKPTPLSQEPVKTTADEPQSLLTLKKKTVQYSTKDMRVSCEAIPEEIAGSTPPSQAAALALQPESGTLPPKQHSADDVSSHVAGGSNLQAGGSTLKLGKPPLSPGQPPLLGTGRVTSFGGTSVPQPGALAKSSSSGSNGTNVGVITSDYDNGNNGNGDMMRGRSKTISVVREVNNGNTRPPPASSFRNFGAAKPPINTKLCMNPSFIFMQLYTTGQLGVTDEPLKVGPENSSAVSLIDLVPPFETHKIGVLYVGQGQCNNEVEILRNSHGSARYVEFLRNIGTLVSLKEAEQNNLFIMLDRNGADGKFAYIWKDDILQVTFHVATLMPTNLQDDPNCNEKKSHIGNDFVKIIYNESGEEYNLNTISGQFNYACVIVEPLDLNSNRVYVKARSEISKFVCHAEYRIVSDRSAPLLARQMALHANLASLVYQSVQKKHPYASNWLERLRKLKRLRSKLIEGLNSQQKSGSASSGIGINASAIGSDMDDQRGDFIKYT
gigas, isoform B
Refseq ID NP_001262089
Protein GI 442633572
UniProt ID M9PD17
mRNA ID NM_001275160
Length 1844
RefSeq Status REVIEWED
MNSKDKSKFKLFLKSLPAGYVGERTLRPEFERELRPEQPVAQRCRMLKELGDTQLHNFNLDESAITILFNLTNDLIVPNKPAETRQIALSFYKRLIHTQYKNLTIMREKFFLVIQNHEAREDLRHLLELLDTLTDNGKDITNFEEKIGKFMLLWIPAITEANLLTPYLDILVNLIKFNAAHLDKDILVGIVQNACDLSCSVTVNEIGLQCLTILEMVIGYTIFPSEPLPQCITTLCRTVNHAPYCPSSFKIMKNLLGTQLGYHSMKMMCSILNDRALYDDAHLLRGAVFHLNMNIFGSNIIFQVSPMTYATNVLTAFLRALDSRQVIVTFEVILSVRMVITKRQLSEIIWDLICDIMSSIVSNIEYYEEVNINKDRLHHLQINFHENIDCIEKLLQQDRSQILGNVERIYDLIERVADRRPEASVLALIEYRSRRVTATRPDWLQVLAQFVRRYYRMSNVNVRIKTIEALVQIMDQNRACYEEEILSRVVLVHLSHIHLESSVQVRVAVARALSNFATHCDTKRCMDLLDILEALINRPFEHTRHGSSSGEGTLAEVTFGLVNNESEISDIIAAVDGLVKVFAIKLHRLPGIHALKIFNILMDHLELHYERPKIFEHISVVRYKIFAWLLKARANGSYHIGYPEGSTEVVKFSPYLGIDSPLLPQAHPTAISIRRVCKLIVRCLEHDTDYQVFQLVIRELPKVLQNKALVQGNDIEELANTLLKINLVSNNKFKRPTDEFHALVLPAIASLVIYHESLQPQQHYGIITALNSRVLTGIASVCINTMTILILEMPEALMRKLPDVLLQMSKMSDTNALATPVLEFLSLLIHLSKHLFANFTSMHNMYVFAITLPYTKPHRYDHYTVSLAHHVIAGWFLKCKLELRRNCVNYIKSSNAKMLSSDIVNLNSLNEDSSNRKRSTSLTERGSRNNANAWNDLEMRPQMNNGLRNFHAELAETCFDFLARHTYSPCPSMPKRLPAAEFLLKDGVSQTWLVGNNLVTITTSGCPSAPARSGLCERCAQLGKAPSISLNSKSLSDAAPPLSPERERRYTKVSLQHSSGNESAGSTELTSSSSSNSAAAGGHPHRQISNSSTASLDALSRRGSNPEALGSALGEGAHTGSNTSLLGNSLSQSSVSMSPSSGSVVQQPVCVRACTGWAEVLVRRPTGNVSWITRIQNPITNDCFGQELPFNNVVSLFLPTAHGGVFGPDNTIQAPPHTLADPEPEPEAEVNAATAPQASALRSRMVAKARALQRQEEIHSVGGNGNGNGNGNGSGNAPSTGGAAAIPIPRVPASGKRGKEAALCGSVSDGEADDDSLAFEDAQSRARNPVRRVNSSPEMSSSWRQSFLTNKPTPLSQEPVKTTADEPQSLLTLKKKTVQYSTKDMRVSCEAIPEEIAGSTPPSQAAALALQPESGTLPPKQHSADDVSSHVAGGSNLQAGGSTLKLGKPPLSPGQPPLLGTGRVTSFGGTSVPQPGALAKSSSSGSNGTNVGVITSDYDNGNNGNGDMMRGRSKTISVVREVNNGNTRPPPASSFRNFGAAKPPINTKLCMNPSFIFMQLYTTGQLGVTDEPLKVGPENSSAVSLIDLVPPFETHKIGVLYVGQGQCNNEVEILRNSHGSARYVEFLRNIGTLVSLKEAEQNNLFIMLDRNGADGKFAYIWKDDILQVTFHVATLMPTNLQDDPNCNEKKSHIGNDFVKIIYNESGEEYNLNTISGQFNYACVIVEPLDLNSNRVYVKARSEISKFVCHAEYRIVSDRSAPLLARQMALHANLASLVYQSVQKKHPYASNWLERLRKLKRLRSKLIEGLNSQQKSGSASSGIGINASAIGSDMDDQRGDFIKYT

Gene Information

Entrez Gene ID
40201
Gene Name
gigas
Gene Symbol
gig
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0033596 IPI:FlyBase C TSC1-TSC2 complex
GO:0005099 IDA:FlyBase F Ras GTPase activator activity
GO:0019900 IPI:FlyBase F kinase binding
GO:0038202 IMP:FlyBase P TORC1 signaling
GO:0006974 IMP:FlyBase P cellular response to DNA damage stimulus
GO:0071456 IMP:FlyBase P cellular response to hypoxia
GO:0008340 IMP:FlyBase P determination of adult lifespan
GO:0035069 IGI:FlyBase P larval midgut histolysis
GO:0046331 IMP:FlyBase P lateral inhibition
GO:0006629 IGI:FlyBase P lipid metabolic process
GO:0032007 IBA:RefGenome P negative regulation of TOR signaling
GO:0030178 IBA:RefGenome P negative regulation of Wnt signaling pathway
GO:0030308 IMP:FlyBase P negative regulation of cell growth
GO:0008285 IGI:FlyBase P negative regulation of cell proliferation
GO:0045792 IMP:FlyBase P negative regulation of cell size
GO:0046627 IGI:FlyBase P negative regulation of insulin receptor signaling pathway
GO:0046621 IGI:FlyBase P negative regulation of organ growth
GO:0051898 IBA:RefGenome P negative regulation of protein kinase B signaling
GO:0045886 IMP:FlyBase P negative regulation of synaptic growth at neuromuscular junction
GO:0048477 IMP:FlyBase P oogenesis
GO:0006909 IMP:FlyBase P phagocytosis
GO:0032320 IDA:FlyBase P positive regulation of Ras GTPase activity
GO:0010508 IMP:FlyBase P positive regulation of autophagy
GO:0001934 IDA:FlyBase P positive regulation of protein phosphorylation
GO:0051726 IMP:FlyBase P regulation of cell cycle
GO:0042325 IDA:FlyBase P regulation of phosphorylation
GO:0007584 IMP:FlyBase P response to nutrient
GO:0007165 IGI:FlyBase P signal transduction

Domain Information

InterPro Annotations

Accession Description
IPR016024 Armadillo-type fold
IPR000331 Rap_GAP_dom
IPR003913 Tuberin
IPR018515 Tuberin-type_domain
IPR024584 Tuberin_N

UniProt Annotations

Entry Information

Gene Name
gigas
Protein Entry
M9PD17_DROME
UniProt ID
Q9VW83
Species
Drosophila

Identical and Related Proteins

Unique RefSeq proteins for LMP008951 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
17737673 RefSeq NP_524177 1847 gigas, isoform A
442633572 RefSeq NP_001262089 1844 gigas, isoform B

Identical Sequences to LMP008951 proteins

Reference Database Accession Length Protein Name
GI:17737673 gnl FlyBase 1847 gigas, isoform A [Drosophila melanogaster]
GI:442633572 gnl FlyBase 1844 gigas, isoform B [Drosophila melanogaster]

Related Sequences to LMP008951 proteins

Reference Database Accession Length Protein Name
GI:17737673 EMBL CCB63117.1 1597 gigas, partial [Drosophila melanogaster]
GI:17737673 EMBL CCB63118.1 1597 gigas, partial [Drosophila melanogaster]
GI:17737673 EMBL CCB63120.1 1597 gigas, partial [Drosophila melanogaster]
GI:17737673 EMBL CCB63121.1 1597 gigas, partial [Drosophila melanogaster]
GI:17737673 GenBank AAD48498.1 1847 gigas protein [Drosophila melanogaster]
GI:17737673 GenBank AAL39748.2 1876 LD36178p, partial [Drosophila melanogaster]
GI:442633572 GenBank EDV39440.1 1828 GF25310 [Drosophila ananassae]
GI:442633572 GenBank EDW19428.1 1904 GI11523 [Drosophila mojavensis]
GI:442633572 GenBank JAD12967.1 1972 hypothetical protein g.3578 [Bactrocera cucurbitae]
GI:442633572 RefSeq XP_001956634.1 1828 GF25310 [Drosophila ananassae]
GI:442633572 RefSeq XP_002008952.1 1904 GI11523 [Drosophila mojavensis]
GI:442633572 RefSeq XP_005183581.1 1892 PREDICTED: tuberin-like [Musca domestica]