Gene/Proteome Database (LMPD)

LMPD ID
LMP008958
Gene ID
38909
Species
Drosophila melanogaster (Drosophila)
Gene Name
N-myristoyl transferase
Gene Symbol
Nmt
Synonyms
153290_at; CG7436; Dmel\CG7436; dNMT; l(3)j1c7; l(3)j1C7; nmt; Nmt1
Alternate Names
CG7436-PA; N-myristoyl transferase; Nmt-PA
Chromosome
3L
Map Location
66B10-66B11
EC Number
2.3.1.97

Proteins

N-myristoyl transferase
Refseq ID NP_523969
Protein GI 17647739
UniProt ID O61613
mRNA ID NM_079245
Length 472
RefSeq Status REVIEWED
MPNENAEDLSGQELKQKAKEVADASEAMLEKVVAGLNIQDTASTNAAGNEDAEQPDGAKNEASVSANASKQALLQAVSDAMASTRQMAKKFAFWSTQPVTKLDEQVTTNECIEPNKEISEIRALPYTLPGGFKWVTLDLNDANDLKELYTLLNENYVEDDDAMFRFDYQPEFLKWSLQPPGWKRDWHVGVRVEKSGKLVGFISAIPSKLKSYDKVLKVVDINFLCVHKKLRSKRVAPVLIREITRRVNLTGIFQAAYTAGVVLPTPVATCRYWHRSLNPKKLVDVRFSHLARNMTMQRTMKLYKLPDQPKTKGYRRITAKDMDKAHKLLEDYLKRFQLSPVFSKEEFRHWFTPKEGIIDCFVVADEKGNITDLTSYYCLPSSVMHHPVHKTVRAAYSFYNVSTKTPWLDLMNDALISARNVQMDVYNALDLMENKKYFAPLKFGAGDGNLQYYLYNWRCPSMQPEEIALILM

Gene Information

Entrez Gene ID
38909
Gene Name
N-myristoyl transferase
Gene Symbol
Nmt
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016020 IDA:UniProtKB C membrane
GO:0004379 ISS:UniProtKB F glycylpeptide N-tetradecanoyltransferase activity
GO:0006499 IDA:FlyBase P N-terminal protein myristoylation
GO:0007391 TAS:FlyBase P dorsal closure
GO:0022008 IMP:FlyBase P neurogenesis

Domain Information

InterPro Annotations

Accession Description
IPR016181 Acyl-CoA N-acyltransferase
IPR000903 Myristoyl-CoA:protein N-myristoyltransferase
IPR022677 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal
IPR022676 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal
IPR022678 Myristoyl-CoA:protein N-myristoyltransferase, conserved site

UniProt Annotations

Entry Information

Gene Name
N-myristoyl transferase
Protein Entry
NMT_DROME
UniProt ID
O61613
Species
Drosophila

Comments

Comment Type Description
Catalytic Activity Tetradecanoyl-CoA + glycylpeptide = CoA + N- tetradecanoylglycylpeptide.
Function Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
Sequence Caution Sequence=AAC08578.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the NMT family. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000269|PubMed:9044045}; Peripheral membrane protein {ECO:0000269|PubMed:9044045}.

Identical and Related Proteins

Unique RefSeq proteins for LMP008958 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
17647739 RefSeq NP_523969 472 N-myristoyl transferase

Identical Sequences to LMP008958 proteins

Reference Database Accession Length Protein Name
GI:17647739 GenBank AAM50823.1 472 LD42276p [Drosophila melanogaster]
GI:17647739 GenBank ABL48107.1 472 Sequence 840 from patent US 7135558
GI:17647739 GenBank ACL84346.1 472 Nmt-PA, partial [synthetic construct]
GI:17647739 GenBank ACL89353.1 472 Nmt-PA [synthetic construct]
GI:17647739 gnl FlyBase 472 N-myristoyl transferase [Drosophila melanogaster]
GI:17647739 SwissProt O61613.2 472 RecName: Full=Glycylpeptide N-tetradecanoyltransferase; AltName: Full=Myristoyl-CoA:protein N-myristoyltransferase; Short=NMT; AltName: Full=Peptide N-myristoyltransferase; AltName: Full=dNMT [Drosophila melanogaster]

Related Sequences to LMP008958 proteins

Reference Database Accession Length Protein Name
GI:17647739 GenBank EDW40658.1 472 GM24964 [Drosophila sechellia]
GI:17647739 GenBank EDW93842.1 472 GE20367 [Drosophila yakuba]
GI:17647739 GenBank EDX09650.1 472 GD13014 [Drosophila simulans]
GI:17647739 RefSeq XP_002029672.1 472 GM24964 [Drosophila sechellia]
GI:17647739 RefSeq XP_002094130.1 472 GE20367 [Drosophila yakuba]
GI:17647739 RefSeq XP_002084065.1 472 GD13014 [Drosophila simulans]