Gene/Proteome Database (LMPD)

LMPD ID
LMP008963
Gene ID
38446
Species
Drosophila melanogaster (Drosophila)
Gene Name
CG12006 gene product from transcript CG12006-RA
Gene Symbol
CG12006
Synonyms
Dmel\CG12006
Alternate Names
CG12006; CG12006-PA; CG12006-PB
Chromosome
3L
Map Location
63F1-63F1
EC Number
2.4.1.-

Proteins

CG12006, isoform A
Refseq ID NP_647832
Protein GI 24656973
UniProt ID Q9VZM5
mRNA ID NM_139575
Length 561
RefSeq Status REVIEWED
MKLIYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLIAGLYKILALLQLDSAHLLVVLPRIVQALLSAYSDYRFFVWTGKRKWALFLILVPWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAVIWLPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASSTMLWTTALVILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTMRFLTCEPNLEKKEQYKDEADRFFEDPVHWINSHIPMHPLTALPTHVVLFDPLAENISVFLRNYRLLHRIEHAEVTRLEGSQALVDQWSEALGAQSPNLASLLQNRQSRTGRSILVYQRLKKGEENAFNRGPDSGQHEPDVHDHPPLEDLVLANENENLFN
CG12006, isoform B
Refseq ID NP_995991
Protein GI 45552929
UniProt ID Q9VZM5
mRNA ID NM_206269
Length 531
RefSeq Status REVIEWED
MKLIYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLIAGLYKILALLQLDSAHLLVVLPRIVQALLSAYSDYRFFVWTGKRKWALFLILVPWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAVIWLPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASSTMLWTTALVILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTMRFLTCEPNLEKKEQYKDEADRFFEDPVHWINSHIPMHPLTALPTHVVLFDPLAENISVFLRNYRLLHRIEHAENRQSRTGRSILVYQRLKKGEENAFNRGPDSGQHEPDVHDHPPLEDLVLANENENLFN

Gene Information

Entrez Gene ID
38446
Gene Name
CG12006 gene product from transcript CG12006-RA
Gene Symbol
CG12006
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005789 ISS:UniProtKB C endoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0000030 ISS:UniProtKB F mannosyltransferase activity
GO:0006506 ISS:UniProtKB P GPI anchor biosynthetic process
GO:0097502 ISS:GOC P mannosylation

KEGG Pathway Links

KEGG Pathway ID Description
dme00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
ko00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
dme01100 Metabolic pathways

REACTOME Pathway Links

REACTOME Pathway ID Description
6226257 Synthesis of glycosylphosphatidylinositol (GPI)

Domain Information

InterPro Annotations

Accession Description
IPR005599 GPI mannosyltransferase

UniProt Annotations

Entry Information

Gene Name
CG12006 gene product from transcript CG12006-RA
Protein Entry
PIGB_DROME
UniProt ID
Q9VZM5
Species
Drosophila

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=A; IsoId=Q9VZM5-1; Sequence=Displayed; Note=No experimental confirmation available.; Name=B; IsoId=Q9VZM5-2; Sequence=VSP_019841; Note=No experimental confirmation available.;
Function Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By similarity). {ECO:0000250}.
Pathway Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
Similarity Belongs to the glycosyltransferase 22 family. PIGB subfamily. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP008963 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
24656973 RefSeq NP_647832 561 CG12006, isoform A
45552929 RefSeq NP_995991 531 CG12006, isoform B

Identical Sequences to LMP008963 proteins

Reference Database Accession Length Protein Name
GI:24656973 GenBank AAO24997.1 561 LD47795p [Drosophila melanogaster]
GI:24656973 GenBank ACL90602.1 561 CG12006-PA [synthetic construct]
GI:24656973 gnl FlyBase 561 CG12006, isoform A [Drosophila melanogaster]
GI:45552929 gnl FlyBase 531 CG12006, isoform B [Drosophila melanogaster]
GI:24656973 SwissProt Q9VZM5.2 561 RecName: Full=GPI mannosyltransferase 3; AltName: Full=GPI mannosyltransferase III; Short=GPI-MT-III [Drosophila melanogaster]

Related Sequences to LMP008963 proteins

Reference Database Accession Length Protein Name
GI:45552929 GenBank AAO24997.1 561 LD47795p [Drosophila melanogaster]
GI:24656973 GenBank EDV50812.1 531 GG15159 [Drosophila erecta]
GI:24656973 GenBank EDW50366.1 531 GM14587 [Drosophila sechellia]
GI:45552929 GenBank ACL90602.1 561 CG12006-PA [synthetic construct]
GI:45552929 gnl FlyBase 561 CG12006, isoform A [Drosophila melanogaster]
GI:24656973 gnl FlyBase 531 CG12006, isoform B [Drosophila melanogaster]
GI:45552929 RefSeq NP_647832.1 561 CG12006, isoform A [Drosophila melanogaster]
GI:24656973 RefSeq NP_995991.1 531 CG12006, isoform B [Drosophila melanogaster]
GI:24656973 RefSeq XP_001971786.1 531 GG15159 [Drosophila erecta]
GI:45552929 RefSeq XP_002035230.1 531 GM14587 [Drosophila sechellia]
GI:24656973 RefSeq XP_002035230.1 531 GM14587 [Drosophila sechellia]
GI:45552929 SwissProt Q9VZM5.2 561 RecName: Full=GPI mannosyltransferase 3; AltName: Full=GPI mannosyltransferase III; Short=GPI-MT-III [Drosophila melanogaster]