Gene/Proteome Database (LMPD)

LMPD ID
LMP008981
Gene ID
32285
Species
Drosophila melanogaster (Drosophila)
Gene Name
Inositol 1,4,5-triphosphate kinase 2
Gene Symbol
IP3K2
Synonyms
CG12724; CG15745; CG1630; CG34359; CG45017; D-IP3K2; DIP3K2; Dmel\CG45017; dmIP3K2; dmIP3Kbeta; dmIP[[3]]beta; IP[[3]]K-2; IP[[3]]K2; NP2758
Chromosome
X
Map Location
11E11-11E11

Proteins

inositol 1,4,5-triphosphate kinase 2, isoform A
Refseq ID NP_572875
Protein GI 24641734
UniProt ID Q9VYE6
mRNA ID NM_132647
Length 669
RefSeq Status REVIEWED
MSVCALSQPQQPNKSNQNQKQKNGPARLPALATGNGSASASASGINLNGKAKGSVTPPTPPPSPQVRIYEDFDRMSAKEVYYNEAGKKVTVKLLHFPDVPPEEISKLKFDDDDDDEEEDGNGGENENGDDDNGEEADEDSDSGRRPTSADSEDAGHKSESSGGASNANALPSSSSKKIFRRKLSGNNMQPRKCSLAFAQAHGIRQRAEKKLSMPTISITANSGEHVAHNCGLRLNLGRKLSQQHSLPLGSPTSPASPTSPGPRRSHSPLGQSLCPGYIQYSKSLLEVPMPRDYGYASSDDLSSEWDSDVSTSAAGSATGSGSGAASQASTTGKKSSGWRKIRNIVQWTPFFQTYKKQRYPWVQLAGHQGNFKAGPEPGTVLKKLCPKEEECFQILMHDLLRPYVPVYKGQVTSEDGELYLQLQDLLSDYVQPCVMDCKVGVRTYLEEELSKAKEKPKLRKDMYDKMIQIDSHAPTAEEHAAKAVTKPRYMVWRETISSTATLGFRIEGIKKSDGTSSKDFKTTKSREQIKLAFLEFLSGHPHILPRYIQRLRAIRATLAVSEFFQTHEVIGSSLLFVHDQTHASIWLIDFAKTVELPPQLRIDHYSAWKVGNHEDGYLIGINNLIDIFVELQASMEAEAHAQAQAEAIQSPVSGSGGDQAEQTGEESKP
inositol 1,4,5-triphosphate kinase 2, isoform B
Refseq ID NP_727688
Protein GI 24641736
UniProt ID Q9VYE6
mRNA ID NM_167358
Length 669
RefSeq Status REVIEWED
Protein sequence is identical to GI:24641734 (mRNA isoform)
inositol 1,4,5-triphosphate kinase 2, isoform C
Refseq ID NP_001096969
Protein GI 161077798
UniProt ID Q9VYE7
mRNA ID NM_001103499
Length 467
RefSeq Status REVIEWED
MALYPSSSRPRTLMEQLLARKIEAAAAAGGAPSAATATPTASGSATPTPSPTSPNPPAVGGMGLPMPLTLGLGLGLGMGMGVVSRLRRTDSLDSTSSLGSLAFGEDVCRCDDCLLGIVDLYVISAAEAAKKKSSGWRKIRNIVQWTPFFQTYKKQRYPWVQLAGHQGNFKAGPEPGTVLKKLCPKEEECFQILMHDLLRPYVPVYKGQVTSEDGELYLQLQDLLSDYVQPCVMDCKVGVRTYLEEELSKAKEKPKLRKDMYDKMIQIDSHAPTAEEHAAKAVTKPRYMVWRETISSTATLGFRIEGIKKSDGTSSKDFKTTKSREQIKLAFLEFLSGHPHILPRYIQRLRAIRATLAVSEFFQTHEVIGSSLLFVHDQTHASIWLIDFAKTVELPPQLRIDHYSAWKVGNHEDGYLIGINNLIDIFVELQASMEAEAHAQAQAEAIQSPVSGSGGDQAEQTGEESKP
inositol 1,4,5-triphosphate kinase 2, isoform D
Refseq ID NP_001285200
Protein GI 665391108
UniProt ID Q9VYE7
mRNA ID NM_001298271
Length 467
RefSeq Status REVIEWED
Protein sequence is identical to GI:161077798 (mRNA isoform)
inositol 1,4,5-triphosphate kinase 2, isoform G
Refseq ID NP_572873
Protein GI 665391113
UniProt ID Q7KV26
mRNA ID NM_132645
Length 691
RefSeq Status REVIEWED
MIVNQQQLSNEGEPKTLPGATASNSDEGCNVTGGGLSPYSSDNEDNSLSPRQRKMKVTRCASSDSALGLDVDDGGMDVPLPPQRRMTLTVTDLPLRPALLPLAEPTALPDSPLTSPTGGGNPSVGVPTKVLLEERVVAAPGSRRESTQSSYSELGVSGLPLGVRYVRTPSVVVSDYSDDITACGISMEEMEYFRLQRARGQRRCSLEAGHHSHSGGHGAHGHGGSGAAGMSPGCGKDDGQSDVSAASSCSNLYYCGSTISALDGGECIVNGVRVALARKSSTQSSSLSDEEEEEEDDDEDRDEQDRDEDDRDAEEMLQEDYERGDRERERERQISELMAATQLGDRQRDRSKKSSGWRKIRNIVQWTPFFQTYKKQRYPWVQLAGHQGNFKAGPEPGTVLKKLCPKEEECFQILMHDLLRPYVPVYKGQVTSEDGELYLQLQDLLSDYVQPCVMDCKVGVRTYLEEELSKAKEKPKLRKDMYDKMIQIDSHAPTAEEHAAKAVTKPRYMVWRETISSTATLGFRIEGIKKSDGTSSKDFKTTKSREQIKLAFLEFLSGHPHILPRYIQRLRAIRATLAVSEFFQTHEVIGSSLLFVHDQTHASIWLIDFAKTVELPPQLRIDHYSAWKVGNHEDGYLIGINNLIDIFVELQASMEAEAHAQAQAEAIQSPVSGSGGDQAEQTGEESKP
inositol 1,4,5-triphosphate kinase 2, isoform H
Refseq ID NP_001285201
Protein GI 665391115
UniProt ID Q9VYE7
mRNA ID NM_001298272
Length 467
RefSeq Status REVIEWED
Protein sequence is identical to GI:161077798 (mRNA isoform)

Gene Information

Entrez Gene ID
32285
Gene Name
Inositol 1,4,5-triphosphate kinase 2
Gene Symbol
IP3K2
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IDA:FlyBase C cytoplasm
GO:0048306 IDA:FlyBase F calcium-dependent protein binding
GO:0005516 IDA:FlyBase F calmodulin binding
GO:0008440 IDA:FlyBase F inositol-1,4,5-trisphosphate 3-kinase activity
GO:0008440 IEA:UniProtKB-EC F inositol-1,4,5-trisphosphate 3-kinase activity
GO:0032958 IDA:FlyBase P inositol phosphate biosynthetic process
GO:0016310 IDA:GOC P phosphorylation

KEGG Pathway Links

KEGG Pathway ID Description
dme00562 Inositol phosphate metabolism
ko00562 Inositol phosphate metabolism
dme_M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
dme01100 Metabolic pathways
dme04070 Phosphatidylinositol signaling system
ko04070 Phosphatidylinositol signaling system

REACTOME Pathway Links

REACTOME Pathway ID Description
6226923 Inositol phosphate metabolism
6225882 Metabolism
6226922 Synthesis of IP3 and IP4 in the cytosol

Domain Information

InterPro Annotations

Accession Description
IPR005522 Inositol polyphosphate kinase

UniProt Annotations

Entry Information

Gene Name
Inositol 1,4,5-triphosphate kinase 2
Protein Entry
Q9VYE7_DROME
UniProt ID
Q9VYE7
Species
Drosophila

Identical and Related Proteins

Unique RefSeq proteins for LMP008981 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
24641734 RefSeq NP_572875 669 inositol 1,4,5-triphosphate kinase 2, isoform A
161077798 RefSeq NP_001096969 467 inositol 1,4,5-triphosphate kinase 2, isoform C
665391113 RefSeq NP_572873 691 inositol 1,4,5-triphosphate kinase 2, isoform G

Identical Sequences to LMP008981 proteins

Reference Database Accession Length Protein Name
GI:24641734 EMBL CAD32600.1 669 unnamed protein product [Drosophila melanogaster]
GI:161077798 GenBank ACO53103.1 467 MIP10054p [Drosophila melanogaster]
GI:24641734 GenBank AEX93143.1 669 FI18235p1 [Drosophila melanogaster]
GI:24641734 gnl FlyBase 669 inositol 1,4,5-triphosphate kinase 2, isoform A [Drosophila melanogaster]
GI:24641734 gnl FlyBase 669 inositol 1,4,5-triphosphate kinase 2, isoform B [Drosophila melanogaster]
GI:161077798 gnl FlyBase 467 inositol 1,4,5-triphosphate kinase 2, isoform C [Drosophila melanogaster]
GI:161077798 gnl FlyBase 467 inositol 1,4,5-triphosphate kinase 2, isoform D [Drosophila melanogaster]
GI:665391113 gnl FlyBase 691 inositol 1,4,5-triphosphate kinase 2, isoform G [Drosophila melanogaster]
GI:161077798 gnl FlyBase 467 inositol 1,4,5-triphosphate kinase 2, isoform H [Drosophila melanogaster]
GI:24641734 RefSeq NP_727688.1 669 inositol 1,4,5-triphosphate kinase 2, isoform B [Drosophila melanogaster]
GI:161077798 RefSeq NP_001285200.1 467 inositol 1,4,5-triphosphate kinase 2, isoform D [Drosophila melanogaster]
GI:161077798 RefSeq NP_001285201.1 467 inositol 1,4,5-triphosphate kinase 2, isoform H [Drosophila melanogaster]

Related Sequences to LMP008981 proteins

Reference Database Accession Length Protein Name
GI:665391113 EMBL CAD32600.1 669 unnamed protein product [Drosophila melanogaster]
GI:161077798 EMBL CAD32600.1 669 unnamed protein product [Drosophila melanogaster]
GI:665391113 GenBank AAL28684.1 372 LD11831p [Drosophila melanogaster]
GI:24641734 GenBank AAL89896.1 669 RE35745p [Drosophila melanogaster]
GI:161077798 GenBank AAU52346.1 397 Sequence 33291 from patent US 6703491
GI:161077798 GenBank AAU67563.1 397 Sequence 48508 from patent US 6703491
GI:161077798 GenBank ACD81772.1 370 IP20622p, partial [Drosophila melanogaster]
GI:24641734 GenBank EDV47212.1 675 GG17771 [Drosophila erecta]
GI:665391113 GenBank EDW49007.1 560 GM11617 [Drosophila sechellia]
GI:24641734 GenBank EDX01560.1 667 GE17061 [Drosophila yakuba]
GI:24641734 GenBank EDX17814.1 670 GD17114 [Drosophila simulans]
GI:665391113 gnl FlyBase 669 inositol 1,4,5-triphosphate kinase 2, isoform A [Drosophila melanogaster]
GI:161077798 RefSeq NP_572875.1 669 inositol 1,4,5-triphosphate kinase 2, isoform A [Drosophila melanogaster]
GI:161077798 RefSeq NP_727688.1 669 inositol 1,4,5-triphosphate kinase 2, isoform B [Drosophila melanogaster]
GI:24641734 RefSeq XP_001978285.1 675 GG17771 [Drosophila erecta]
GI:665391113 RefSeq XP_002042917.1 560 GM11617 [Drosophila sechellia]
GI:24641734 RefSeq XP_002106846.1 670 GD17114 [Drosophila simulans]
GI:665391113 RefSeq XP_004531114.1 1318 PREDICTED: serine-rich adhesin for platelets-like [Ceratitis capitata]