Gene/Proteome Database (LMPD)

LMPD ID
LMP008986
Gene ID
43991
Species
Drosophila melanogaster (Drosophila)
Gene Name
CG5671 gene product from transcript CG5671-RB
Gene Symbol
Pten
Synonyms
CG5671; Dmel\CG5671; dpten; dPten; dPTEN; DPTEN; pten; PTEN; PTEN3
Chromosome
2L
Map Location
31B1-31B1

Proteins

pten, isoform A
Refseq ID NP_599147
Protein GI 19549660
UniProt ID Q9V3L4
mRNA ID NM_134320
Length 509
RefSeq Status REVIEWED
MANTISLMSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKLVCSSVPYSKVSLNVCEIRFSESSCVQNLGMVECSISVLHDSATENAKPDRLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKKSPDKIICHFWLNTFFVRNYSPCESDGTVNKYIHTLSKSEIDDVHKDSEHKRFSEEFKISIVFEAENFSNDVQAEASEKERNENVLNFERSDYDSLSPNCYAEKKVLTAIVNDNTTKSQTIETLDHKDIVTKIQYDTSTNSKNTSTACKRKQPNSKTLLPSLNDSTKEEIKRNHIFNQPSIKKTDLIKWQNSEVHITSDTRSINENKNINYNSYITCKQSSPKFNCGTEDGEEDWESE
pten, isoform B
Refseq ID NP_477423
Protein GI 17137658
UniProt ID Q7KMQ6
mRNA ID NM_058075
Length 514
RefSeq Status REVIEWED
Protein sequence is identical to GI:281364767 (mRNA isoform)
pten, isoform C
Refseq ID NP_477424
Protein GI 17137660
UniProt ID Q9Y0B6
mRNA ID NM_058076
Length 418
RefSeq Status REVIEWED
MANTISLMSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKLVCSSVPYSKVSLNVCEIRFSESSCVQNLGMVECSISVLHDSATENAKPDRLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKKSPDKIICHFWLNTFFVRNYSPCESDGTVNKYIHTLSKSEIDDVHKDSEHKRFSEEFKISIVFEAENFSNDVQAEASEKERNENVLNFERSDYDSLSPNCYAEKKVLTAIVNDNTTKSQTIETLDHKDIVVNQHTCNQCLLRTYNSW
pten, isoform D
Refseq ID NP_599149
Protein GI 19549666
UniProt ID Q7KMQ6
mRNA ID NM_134322
Length 514
RefSeq Status REVIEWED
MANTISLMSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKLVCSSVPYSKVSLNVCEIRFSESSCVQNLGMVECSISVLHDSATENAKPDRLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKKSPDKIICHFWLNTFFVRNYSPCESDGTVNKYIHTLSKSEIDDVHKDSEHKRFSEEFKISIVFEAENFSNDVQAEASEKERNENVLNFERSDYDSLSPNCYAEKKVLTAIVNDNTTKSQTIETLDHKDIVTKIQYDTSTNSKNTSTACKRKQPNSKTLLPSLNDSTKEEIKRNHIFNQPSIKKTDLIKWQNSEVHITSDTRSINENKNINYNSYITCKQSSPKFNCGTEDGEEDWESGESTYL
pten, isoform E
Refseq ID NP_599148
Protein GI 19549663
UniProt ID Q9V3L4
mRNA ID NM_134321
Length 509
RefSeq Status REVIEWED
Protein sequence is identical to GI:19549660 (mRNA isoform)
pten, isoform G
Refseq ID NP_001162933
Protein GI 281364767
UniProt ID Q7KMQ6
mRNA ID NM_001169462
Length 514
RefSeq Status REVIEWED
MANTISLMSNVIRNVVSKKRIRYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKIYNLCSERSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKLVCSSVPYSKVSLNVCEIRFSESSCVQNLGMVECSISVLHDSATENAKPDRLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKKSPDKIICHFWLNTFFVRNYSPCESDGTVNKYIHTLSKSEIDDVHKDSEHKRFSEEFKISIVFEAENFSNDVQAEASEKERNENVLNFERSDYDSLSPNCYAEKKVLTAIVNDNTTKSQTIETLDHKDIVTKIQYDTSTNSKNTSTACKRKQPNSKTLLPSLNDSTKEEIKRNHIFNQPSIKKTDLIKWQNSEVHITSDTRSINENKNINYNSYITCKQSSPKFNCGTEDGEEDWESGESTYL
pten, isoform H
Refseq ID NP_477422
Protein GI 281364769
UniProt ID Q7KMQ6
mRNA ID NM_058074
Length 514
RefSeq Status REVIEWED
Protein sequence is identical to GI:281364767 (mRNA isoform)

Gene Information

Entrez Gene ID
43991
Gene Name
CG5671 gene product from transcript CG5671-RB
Gene Symbol
Pten
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 TAS:Reactome C cytosol
GO:0003779 ISS:FlyBase F actin binding
GO:0004726 ISS:FlyBase F non-membrane spanning protein tyrosine phosphatase activity
GO:0016314 IGI:FlyBase F phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
GO:0004721 IMP:FlyBase F phosphoprotein phosphatase activity
GO:0004722 IMP:FlyBase F protein serine/threonine phosphatase activity
GO:0008138 ISS:FlyBase F protein tyrosine/serine/threonine phosphatase activity
GO:0030036 IMP:FlyBase P actin cytoskeleton organization
GO:0007015 IMP:FlyBase P actin filament organization
GO:0006915 IMP:FlyBase P apoptotic process
GO:0006914 IMP:FlyBase P autophagy
GO:0007155 IMP:FlyBase P cell adhesion
GO:0008283 IMP:FlyBase P cell proliferation
GO:0009987 IMP:FlyBase P cellular process
GO:0034613 IMP:FlyBase P cellular protein localization
GO:0007010 IMP:FlyBase P cytoskeleton organization
GO:0031104 IMP:FlyBase P dendrite regeneration
GO:0007425 IMP:FlyBase P epithelial cell fate determination, open tracheal system
GO:0008286 IGI:FlyBase P insulin receptor signaling pathway
GO:0002164 IMP:FlyBase P larval development
GO:0035069 IGI:FlyBase P larval midgut histolysis
GO:0007436 IMP:FlyBase P larval salivary gland morphogenesis
GO:0006629 IMP:FlyBase P lipid metabolic process
GO:0019915 IMP:FlyBase P lipid storage
GO:0035011 IMP:FlyBase P melanotic encapsulation of foreign target
GO:0007552 IMP:FlyBase P metamorphosis
GO:0048681 IMP:FlyBase P negative regulation of axon regeneration
GO:0045786 TAS:FlyBase P negative regulation of cell cycle
GO:0030308 NAS:FlyBase P negative regulation of cell growth
GO:0045792 TAS:FlyBase P negative regulation of cell size
GO:0045926 TAS:FlyBase P negative regulation of growth
GO:0046627 NAS:FlyBase P negative regulation of insulin receptor signaling pathway
GO:0040015 IMP:FlyBase P negative regulation of multicellular organism growth
GO:0046621 IMP:FlyBase P negative regulation of organ growth
GO:0016322 IMP:FlyBase P neuron remodeling
GO:0009887 IMP:FlyBase P organ morphogenesis
GO:0035335 ISS:GOC P peptidyl-tyrosine dephosphorylation
GO:0046856 NAS:FlyBase P phosphatidylinositol dephosphorylation
GO:0006470 IMP:FlyBase P protein dephosphorylation
GO:0010506 IMP:FlyBase P regulation of autophagy
GO:1901888 IMP:FlyBase P regulation of cell junction assembly
GO:0008360 IMP:FlyBase P regulation of cell shape
GO:0008361 IMP:FlyBase P regulation of cell size
GO:0050773 IMP:FlyBase P regulation of dendrite development
GO:0090175 IMP:FlyBase P regulation of establishment of planar polarity
GO:0035206 IMP:FlyBase P regulation of hemocyte proliferation
GO:0040014 IMP:FlyBase P regulation of multicellular organism growth
GO:0046620 NAS:FlyBase P regulation of organ growth
GO:0042594 IMP:FlyBase P response to starvation
GO:0042052 IMP:FlyBase P rhabdomere development
GO:0007525 IMP:FlyBase P somatic muscle development
GO:0009888 IMP:FlyBase P tissue development

Domain Information

InterPro Annotations

Accession Description
IPR000008 C2 domain
IPR000340 Dual specificity phosphatase, catalytic domain
IPR016130 Protein-tyrosine phosphatase, active site
IPR029021 Protein-tyrosine phosphatase-like
IPR014020 Tensin phosphatase, C2 domain
IPR029023 Tensin phosphatase, lipid phosphatase domain

UniProt Annotations

Entry Information

Gene Name
CG5671 gene product from transcript CG5671-RB
Protein Entry
Q7KMQ6_DROME
UniProt ID
Q9Y0B6
Species
Drosophila

Identical and Related Proteins

Unique RefSeq proteins for LMP008986 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
19549660 RefSeq NP_599147 509 pten, isoform A
17137660 RefSeq NP_477424 418 pten, isoform C
19549666 RefSeq NP_599149 514 pten, isoform D
281364767 RefSeq NP_001162933 514 pten, isoform G

Identical Sequences to LMP008986 proteins

Reference Database Accession Length Protein Name
GI:17137660 GenBank AAD45362.1 418 PTEN1 [Drosophila melanogaster]
GI:19549660 GenBank AAD45364.1 509 PTEN3 [Drosophila melanogaster]
GI:19549660 GenBank AAF23235.1 509 phosphatase and tensin homolog [Drosophila melanogaster]
GI:19549666 GenBank ABE73224.1 514 IP16020p [Drosophila melanogaster]
GI:281364767 GenBank ABE73224.1 514 IP16020p [Drosophila melanogaster]
GI:19549660 gnl FlyBase 509 pten, isoform E [Drosophila melanogaster]
GI:19549660 gnl FlyBase 509 pten, isoform A [Drosophila melanogaster]
GI:17137660 gnl FlyBase 418 pten, isoform C [Drosophila melanogaster]
GI:281364767 gnl FlyBase 514 pten, isoform B [Drosophila melanogaster]
GI:19549666 gnl FlyBase 514 pten, isoform B [Drosophila melanogaster]
GI:19549666 gnl FlyBase 514 pten, isoform G [Drosophila melanogaster]
GI:281364767 gnl FlyBase 514 pten, isoform G [Drosophila melanogaster]
GI:281364767 gnl FlyBase 514 pten, isoform H [Drosophila melanogaster]
GI:19549666 gnl FlyBase 514 pten, isoform H [Drosophila melanogaster]
GI:19549660 RefSeq NP_599148.1 509 pten, isoform E [Drosophila melanogaster]
GI:281364767 RefSeq NP_599149.1 514 pten, isoform D [Drosophila melanogaster]
GI:19549666 RefSeq NP_001162933.1 514 pten, isoform G [Drosophila melanogaster]
GI:19549666 RefSeq NP_477422.2 514 pten, isoform H [Drosophila melanogaster]
GI:281364767 RefSeq NP_477422.2 514 pten, isoform H [Drosophila melanogaster]

Related Sequences to LMP008986 proteins

Reference Database Accession Length Protein Name
GI:19549666 GenBank AAD45363.1 511 PTEN2 [Drosophila melanogaster]
GI:281364767 GenBank AAD45363.1 511 PTEN2 [Drosophila melanogaster]
GI:19549666 GenBank AAD45364.1 509 PTEN3 [Drosophila melanogaster]
GI:17137660 GenBank AAD45364.1 509 PTEN3 [Drosophila melanogaster]
GI:281364767 GenBank AAD45364.1 509 PTEN3 [Drosophila melanogaster]
GI:17137660 GenBank AAF23235.1 509 phosphatase and tensin homolog [Drosophila melanogaster]
GI:281364767 GenBank AAF23235.1 509 phosphatase and tensin homolog [Drosophila melanogaster]
GI:19549666 GenBank AAF23235.1 509 phosphatase and tensin homolog [Drosophila melanogaster]
GI:19549660 GenBank ABE73224.1 514 IP16020p [Drosophila melanogaster]
GI:19549660 gnl FlyBase 514 pten, isoform D [Drosophila melanogaster]
GI:19549666 gnl FlyBase 509 pten, isoform E [Drosophila melanogaster]
GI:17137660 gnl FlyBase 509 pten, isoform E [Drosophila melanogaster]
GI:281364767 gnl FlyBase 509 pten, isoform E [Drosophila melanogaster]
GI:17137660 gnl FlyBase 509 pten, isoform A [Drosophila melanogaster]
GI:19549660 gnl FlyBase 514 pten, isoform B [Drosophila melanogaster]
GI:19549660 gnl FlyBase 514 pten, isoform G [Drosophila melanogaster]
GI:19549660 RefSeq NP_477423.1 514 pten, isoform B [Drosophila melanogaster]
GI:17137660 RefSeq NP_599147.1 509 pten, isoform A [Drosophila melanogaster]
GI:19549666 RefSeq NP_599147.1 509 pten, isoform A [Drosophila melanogaster]
GI:281364767 RefSeq NP_599147.1 509 pten, isoform A [Drosophila melanogaster]
GI:281364767 RefSeq NP_599148.1 509 pten, isoform E [Drosophila melanogaster]
GI:19549666 RefSeq NP_599148.1 509 pten, isoform E [Drosophila melanogaster]
GI:17137660 RefSeq NP_599148.1 509 pten, isoform E [Drosophila melanogaster]
GI:19549660 RefSeq NP_599149.1 514 pten, isoform D [Drosophila melanogaster]