Gene/Proteome Database (LMPD)

LMPD ID
LMP009104
Gene ID
32601
Species
Drosophila melanogaster (Drosophila)
Gene Name
small wing
Gene Symbol
sl
Synonyms
CG4200; Dmel\CG4200; DPLCgamma; p145; PLC; PLC&ygr;; plc-gamma; PLC-gamma; PLC-gamma D; plc-gammad; PLC-gammaD; Plcgamma; PLCgamma; PLCgammaDmel
Chromosome
X
Map Location
14B15-14B17

Proteins

small wing
Refseq ID NP_476726
Protein GI 45549030
UniProt ID Q9VXH3
mRNA ID NM_057378
Length 1236
RefSeq Status REVIEWED
MSCFSAMSAPLLGEMEQTIGMLERGTIVTKLYGKQRRPDRRHLMLIRETRQLLWATVATQTPRTDYEGAIQLREIREIRVGKHSKEFRLFADDCQRFESSKCFVILHGNHFKLKSFSVVALSEIEADNWVRGLRYMVKDTLGAPYPLQIDRWLRREYYQIENVNTHSAKATEQSPAQVTIKDFKLFLAGVSCKMTTGKFMEHFTEDVRRKHDLKFDDFSRLYQKLLLPNGFASVLSGSGVANFPYSEDQQVVRPAELKQFLETEQRDVSASEISSAAIASFIRDFVQDVERDVQEPYLTFPEFVDFLFSKQNDLWNSKYDQVFMDMNLPLSSYWIASSHNTYLTGDQFSSESSCEAYARALRMGCRCIELDCWNGPDNLPYIFHGHTITSKIKFMDVIKTIKDHAFTSSEYPVILSIEQNCSLEQQRNMAQALIEVFGDMLLTQPCDRNEQHLPSPYQLRRKIILKHKKLPQFDDIANGISSTGSLGHRSSLGGAGGGAHGENDGENVRKVFKEGLLYFKDPVDKSWNLYQFVLTHQELIYSSEINESRNGNSEDDDFGLSSSCSLNSNMQQKQKDTSANDELHFGENWFHGKLEGGRKEADDLLKKYKHFGDGTFLVRESATFVGDYSLSFWRRNRPNHCRIKLKHENGSIKYYLVENFVFDSLYSLIVYYRKNMLRSSEFSIILKEPVPQPKKHEDQEWFHPNTTKEQAEQGLYRLEIGSFLVRPSVQSINAFVISFTINRKIKHCRIMQEGRLYGIDTMNFESLVSLINYYTRNPLYRNVKLSHPVSQELLRQALAEAAQGDHSGGHDDNGASNYMGSNLEENVTCKALYSYKANKPDELSFPKHAIITNVQRDNSMWWIGDYGGMIKKHLPANYVKVIDSTTEDYNSLNEEGTDGRTDSIEIFGAVASLFESNDPGIIFKLQIQTPTMQNPFVIGFDNQETAYEWIKAIQEAALIASQLASERRKKERTARVAKEMSDLIIYFRSVPFREHSWIFQEMSSFPETKAEKQFFQQNTQLFLSYHRNQISRVYPKGQRLDSSNFNPMPFWNVGSQMIALNYQTGDKAMQLNQAKFRNNGQCGYILKPSFMKSDSFNPNNPLCDGLSEVKVSIRLIAARHLFRGGKSNNPQIVVELIGASFDTGVKYRTKVNENGFNPVWNESCEFNVRNPQFAILRFEVQDEDMFAETHFIAQACYPLTCIRQGYRSVILRNKFSEELELSSLLINIKIANVTAP

Gene Information

Entrez Gene ID
32601
Gene Name
small wing
Gene Symbol
sl
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004435 IEA:UniProtKB-EC F phosphatidylinositol phospholipase C activity
GO:0004871 IEA:UniProtKB-KW F signal transducer activity
GO:0007298 IGI:FlyBase P border follicle cell migration
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0045596 IMP:FlyBase P negative regulation of cell differentiation
GO:0042059 IGI:FlyBase P negative regulation of epidermal growth factor receptor signaling pathway
GO:0009395 IEA:InterPro P phospholipid catabolic process
GO:0030307 IMP:FlyBase P positive regulation of cell growth
GO:0032868 IGI:FlyBase P response to insulin

Domain Information

InterPro Annotations

Accession Description
IPR000008 C2 domain
IPR011992 EF-hand domain pair
IPR016279 Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma
IPR001192 Phosphoinositide phospholipase C family
IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
IPR001849 Pleckstrin homology domain
IPR011993 Pleckstrin homology-like domain
IPR000980 SH2 domain
IPR001452 SH3_domain

UniProt Annotations

Entry Information

Gene Name
small wing
Protein Entry
Q9VXH3_DROME
UniProt ID
Q9VXH3
Species
Drosophila

Comments

Comment Type Description
Catalytic Activity 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
Similarity Contains 1 C2 domain.
Similarity Contains 1 PH domain.
Similarity Contains 1 PI-PLC X-box domain.
Similarity Contains 1 PI-PLC Y-box domain.
Similarity Contains 1 SH3 domain.
Similarity Contains C2 domain.
Similarity Contains Cdomain.
Similarity Contains PH domain.
Similarity Contains PI-PLC X-box domain.
Similarity Contains PI-PLC Y-box domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP009104 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
45549030 RefSeq NP_476726 1236 small wing

Identical Sequences to LMP009104 proteins

Reference Database Accession Length Protein Name
GI:45549030 EMBL CBF74729.1 1236 unnamed protein product [Drosophila melanogaster]
GI:45549030 EMBL CBF62964.1 1236 unnamed protein product [Drosophila melanogaster]
GI:45549030 EMBL CBU87840.1 1236 unnamed protein product [Drosophila melanogaster]
GI:45549030 EMBL CBU96787.1 1236 unnamed protein product [Drosophila melanogaster]
GI:45549030 GenBank AGX54775.1 1236 Sequence 9906 from patent US 8541208
GI:45549030 GenBank AGX64215.1 1236 Sequence 28540 from patent US 8541208

Related Sequences to LMP009104 proteins

Reference Database Accession Length Protein Name
GI:45549030 DBBJ BAA06189.1 1230 PLC-gamma D [Drosophila melanogaster]
GI:45549030 GenBank EDV46880.1 1236 GG17956 [Drosophila erecta]
GI:45549030 GenBank EDX01907.1 1233 GE17264 [Drosophila yakuba]
GI:45549030 RefSeq XP_001977953.1 1236 GG17956 [Drosophila erecta]
GI:45549030 RefSeq XP_002100799.1 1233 GE17264 [Drosophila yakuba]
GI:45549030 RefSeq XP_002134355.1 1250 small-wing [Drosophila pseudoobscura pseudoobscura]