Gene/Proteome Database (LMPD)

LMPD ID
LMP009108
Gene ID
42446
Species
Drosophila melanogaster (Drosophila)
Gene Name
CG4141 gene product from transcript CG4141-RB
Gene Symbol
Pi3K92E
Synonyms
anon-92Ed; CG4141; Dmel\CG4141; Dmp110; dp110; dP110; Dp110; DP110; Dp110/PI3K; dp110alpha; dPI3K; dPI3K[92E]; p110; p120; PI(3)K; PI-3 kinase; PI-3-K', "PI3'K", 'Pi3k; Pi3K; PI3k; PI3K; PI3K-92D; PI3K-92E/Dp110; PI3K-dp110; PI3K-Dp110; Pi3K92D; PI3K92E; Pi3K92E|p110; Pi3Kp110; PiK92E; PI[[3]]K; rea; type-1 PI3K
Chromosome
3R
Map Location
92F3-92F3

Proteins

Pi3K92E, isoform A
Refseq ID NP_650902
Protein GI 21356197
UniProt ID P91634
mRNA ID NM_142645
Length 1088
RefSeq Status REVIEWED
Protein sequence is identical to GI:442620113 (mRNA isoform)
Pi3K92E, isoform B
Refseq ID NP_732536
Protein GI 24648472
UniProt ID P91634
mRNA ID NM_169910
Length 1088
RefSeq Status REVIEWED
Protein sequence is identical to GI:442620113 (mRNA isoform)
Pi3K92E, isoform C
Refseq ID NP_001262770
Protein GI 442620113
UniProt ID P91634
mRNA ID NM_001275841
Length 1088
RefSeq Status REVIEWED
MNMMDNRALAYVAHQPKYETPPEEAEPPCMRFSVNLWKNEMLNWVDLICLLPNGFLLELRVNPANTIQVIKVEMVNQAKQMPLGYVIKEACEYQVYGISTFNIEPYTDETKRLSEVQPYFGILSLGERTDTTSFSSDYELTKMVNGMIGTTFDHNRTHGSPEIDDFRLYMTQTCDNIELERSAYTWQQRLLYEHPLRLANSTKMPELIRERHPTRTFLIVVKNENDQSTFTLSVNEQDTPFSLTESTLQKMNRSQMKMNDRTSDYILKVSGRDEYLLGDYPLIQFLYIQEMLSDSAVPNVVLQSVYRLESYINHHNEQAMVTKRPLPKKRTVHLHKSISSLWDMGNYFQLTLHSISNVNFDKTRALKVGVHVCLYHGDKKLCAQRSTDSPNGNFDTFLFNDLVMDFDIQMRNLPRMTRLCIVIFEVTKMSRSKKSSNNKDIALKDVPYNKNPLAWVNTTIFDHKDILRTGRHTLYTWTYADDIQSVEVFHPLGTIEPNPRKEECALVDLTFLSSGTGTVRYPSEEVVLQYAADREQVNRLQRQLAGPEKPIKELKELMANYTGLDKIYEMVDQDRNAIWERRNDILRELPEELSILLHCVYWKERDDVADMWYLLKQWPLISIERSLELLDYAYPDPAVRRFAIRCLHFLKDEDLLLYLLQLVQAIKHESYLESDLVVFLLERALRNQRIGHYFFWHLRSEMQTPSMQTRFGLLLEVYLKGCKHHVAPLRKQLHVLEKLKQGSLIAKKGSKEKVKTMLQDFLRDQRNSAVFQNIQNPLNPSFRCSGVTPDRCKVMDSKMRPLWVVFENADVNASDVHIIFKNGDDLRQDMLTLQMLRVMDQLWKRDGMDFRMNIYNCISMEKSLGMIEVVRHAETIANIQKEKGMFSATSPFKKGSLLSWLKEHNKPADKLNKAINEFTLSCAGYCVATYVLGVADRHSDNIMVKRNGQLFHIDFGHILGHFKEKLGVRRERVPFVLTHDFVYVINKGFNDRESKEFCHFQELCERAFLVLRKHGCLILSLFSMMISTGLPELSSEKDLDYLRETLVLDYTEEKAREHFRAKFSEALANSWKTSLNWASHNFSKNNKQ

Gene Information

Entrez Gene ID
42446
Gene Name
CG4141 gene product from transcript CG4141-RB
Gene Symbol
Pi3K92E
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 TAS:Reactome C cytosol
GO:0005943 IPI:FlyBase C phosphatidylinositol 3-kinase complex, class IA
GO:0005886 IBA:RefGenome C plasma membrane
GO:0016303 IDA:FlyBase F 1-phosphatidylinositol-3-kinase activity
GO:0035005 IDA:FlyBase F 1-phosphatidylinositol-4-phosphate 3-kinase activity
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0017124 IPI:FlyBase F SH3 domain binding
GO:0001727 IDA:FlyBase F lipid kinase activity
GO:0046934 IDA:FlyBase F phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0006914 IMP:FlyBase P autophagy
GO:0005975 IMP:FlyBase P carbohydrate metabolic process
GO:0016049 TAS:FlyBase P cell growth
GO:0009267 IMP:FlyBase P cellular response to starvation
GO:0048813 IDA:FlyBase P dendrite morphogenesis
GO:0055115 IMP:FlyBase P entry into diapause
GO:0007390 IMP:FlyBase P germ-band shortening
GO:0002168 IMP:FlyBase P instar larval development
GO:0008286 NAS:FlyBase P insulin receptor signaling pathway
GO:0002164 IMP:FlyBase P larval development
GO:0030536 IMP:FlyBase P larval feeding behavior
GO:0007436 IMP:FlyBase P larval salivary gland morphogenesis
GO:0006629 IMP:FlyBase P lipid metabolic process
GO:0007552 IMP:FlyBase P metamorphosis
GO:0035264 IMP:FlyBase P multicellular organism growth
GO:0010507 IMP:FlyBase P negative regulation of autophagy
GO:0042059 IGI:FlyBase P negative regulation of epidermal growth factor receptor signaling pathway
GO:0016322 IMP:FlyBase P neuron remodeling
GO:0048477 IMP:FlyBase P oogenesis
GO:0046854 IDA:FlyBase P phosphatidylinositol phosphorylation
GO:0036092 IDA:GOC P phosphatidylinositol-3-phosphate biosynthetic process
GO:0048015 IEA:InterPro P phosphatidylinositol-mediated signaling
GO:0016310 NAS:FlyBase P phosphorylation
GO:0030307 NAS:FlyBase P positive regulation of cell growth
GO:0045793 IMP:FlyBase P positive regulation of cell size
GO:0045927 TAS:FlyBase P positive regulation of growth
GO:0045572 IMP:FlyBase P positive regulation of imaginal disc growth
GO:0046622 IMP:FlyBase P positive regulation of organ growth
GO:0045727 IMP:FlyBase P positive regulation of translation
GO:0042127 IMP:FlyBase P regulation of cell proliferation
GO:0008361 IMP:FlyBase P regulation of cell size
GO:0050773 IMP:FlyBase P regulation of dendrite development
GO:0048169 IDA:FlyBase P regulation of long-term neuronal synaptic plasticity
GO:0007346 IMP:FlyBase P regulation of mitotic cell cycle
GO:0040014 IMP:FlyBase P regulation of multicellular organism growth
GO:0046620 NAS:FlyBase P regulation of organ growth
GO:2000377 IGI:FlyBase P regulation of reactive oxygen species metabolic process
GO:0051823 IMP:FlyBase P regulation of synapse structural plasticity
GO:0006979 IMP:FlyBase P response to oxidative stress
GO:0060074 IDA:FlyBase P synapse maturation
GO:0051124 IMP:FlyBase P synaptic growth at neuromuscular junction

Domain Information

InterPro Annotations

Accession Description
IPR016024 Armadillo-type fold
IPR000008 C2 domain
IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain
IPR000341 Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain
IPR003113 Phosphatidylinositol 3-kinase adaptor-binding (PI3K ABD) domain
IPR002420 Phosphatidylinositol 3-kinase, C2 domain
IPR018936 Phosphatidylinositol 3/4-kinase, conserved site
IPR015433 Phosphatidylinositol Kinase
IPR001263 Phosphoinositide 3-kinase, accessory (PIK) domain
IPR011009 Protein kinase-like domain
IPR029071 Ubiquitin-related domain

UniProt Annotations

Entry Information

Gene Name
CG4141 gene product from transcript CG4141-RB
Protein Entry
P91634_DROME
UniProt ID
P91634
Species
Drosophila

Comments

Comment Type Description
Similarity Contains PI3K/PI4K domain.
Similarity Contains PIK helical domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP009108 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
442620113 RefSeq NP_001262770 1088 Pi3K92E, isoform C

Identical Sequences to LMP009108 proteins

Reference Database Accession Length Protein Name
GI:442620113 EMBL CCB63082.1 1088 hypothetical protein [Drosophila melanogaster]
GI:442620113 EMBL CCB63083.1 1088 hypothetical protein [Drosophila melanogaster]
GI:442620113 EMBL CCB63084.1 1088 hypothetical protein [Drosophila melanogaster]
GI:442620113 EMBL CCB63085.1 1088 hypothetical protein [Drosophila melanogaster]
GI:442620113 EMBL CCB63086.1 1088 hypothetical protein [Drosophila melanogaster]
GI:442620113 gnl FlyBase 1088 Pi3K92E, isoform C [Drosophila melanogaster]

Related Sequences to LMP009108 proteins

Reference Database Accession Length Protein Name
GI:442620113 EMBL CCB63075.1 1088 hypothetical protein [Drosophila melanogaster]
GI:442620113 EMBL CCB63078.1 1088 hypothetical protein [Drosophila melanogaster]
GI:442620113 EMBL CCB63081.1 1088 hypothetical protein [Drosophila melanogaster]
GI:442620113 GenBank EDW49640.1 1088 GM23175 [Drosophila sechellia]
GI:442620113 RefSeq XP_002043456.1 1088 GM23175 [Drosophila sechellia]
GI:442620113 RefSeq XP_002102701.1 1079 GD20048 [Drosophila simulans]