Gene/Proteome Database (LMPD)

LMPD ID
LMP009115
Gene ID
43104
Species
Drosophila melanogaster (Drosophila)
Gene Name
cardiolipin synthase
Gene Symbol
CLS
Synonyms
CG4774; Dmel\CG4774
Chromosome
3R
Map Location
96E10-96E10

Proteins

cardiolipin synthase, isoform A
Refseq ID NP_651418
Protein GI 24650126
UniProt ID Q8MZC4
mRNA ID NM_143161
Length 322
RefSeq Status REVIEWED
Protein sequence is identical to GI:442621178 (mRNA isoform)
cardiolipin synthase, isoform B
Refseq ID NP_733116
Protein GI 24650128
UniProt ID Q8MZC4
mRNA ID NM_170237
Length 322
RefSeq Status REVIEWED
Protein sequence is identical to GI:442621178 (mRNA isoform)
cardiolipin synthase, isoform C
Refseq ID NP_733117
Protein GI 24650130
UniProt ID Q8MZC4
mRNA ID NM_170238
Length 322
RefSeq Status REVIEWED
Protein sequence is identical to GI:442621178 (mRNA isoform)
cardiolipin synthase, isoform D
Refseq ID NP_001262969
Protein GI 442621178
UniProt ID Q8MZC4
mRNA ID NM_001276040
Length 322
RefSeq Status REVIEWED
MLPAIIFRQVQRPLHHGAATLEHVLGVGGSSFVNCLNRYAAATGFIRISFLDIKRRRNYELARLRLYADEKKQSLHLRTLQGRHLLQGVIERKNFLVDDIREARHKVQERVREKIDEIREERENIMTIPNMLTISRAVLSPYIGYVIVQGDFTLGMSLLAFAGITDLLDGQIARRWPSQASKFGSFLDPMADKLLMGSLVISLCYTDLLPMWLMGIVVFRDVFLLGAGFVIRYISLPPPKTFSRYFDATHVTAQLEPTLLSKINTGVQLATIGLSLGAPIWNYLDHPALQGLWYLTGLTTAATALSYVMNRHNTFKIIQKKT

Gene Information

Entrez Gene ID
43104
Gene Name
cardiolipin synthase
Gene Symbol
CLS
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005743 IEA:UniProtKB-KW C mitochondrial inner membrane
GO:0008808 IDA:FlyBase F cardiolipin synthase activity
GO:0006754 IDA:FlyBase P ATP biosynthetic process
GO:0007006 IDA:FlyBase P mitochondrial membrane organization
GO:0008654 IEA:UniProtKB-KW P phospholipid biosynthetic process

Domain Information

InterPro Annotations

Accession Description
IPR000462 CDP-alcohol phosphatidyltransferase

UniProt Annotations

Entry Information

Gene Name
cardiolipin synthase
Protein Entry
Q8MZC4_DROME
UniProt ID
Q8MZC4
Species
Drosophila

Comments

Comment Type Description
Catalytic Activity 2 Phosphatidylglycerol = diphosphatidylglycerol + glycerol.
Function Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Similarity Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
Subcellular Location Mitochondrion inner membrane ; Multi-pass membrane protein .

Identical and Related Proteins

Unique RefSeq proteins for LMP009115 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
442621178 RefSeq NP_001262969 322 cardiolipin synthase, isoform D

Identical Sequences to LMP009115 proteins

Reference Database Accession Length Protein Name
GI:442621178 EMBL CAY37227.1 322 unnamed protein product [Drosophila melanogaster]
GI:442621178 GenBank ACL87496.1 322 CG4774-PA, partial [synthetic construct]
GI:442621178 gnl FlyBase 322 cardiolipin synthase, isoform D [Drosophila melanogaster]
GI:442621178 RefSeq NP_733116.1 322 cardiolipin synthase, isoform B [Drosophila melanogaster]
GI:442621178 RefSeq NP_733117.1 322 cardiolipin synthase, isoform C [Drosophila melanogaster]
GI:442621178 SwissProt Q8MZC4.1 322 RecName: Full=Probable cardiolipin synthase; Short=CLS [Drosophila melanogaster]

Related Sequences to LMP009115 proteins

Reference Database Accession Length Protein Name
GI:442621178 GenBank EDV53631.1 322 GG12226 [Drosophila erecta]
GI:442621178 GenBank EDW45025.1 322 GM10226 [Drosophila sechellia]
GI:442621178 GenBank EDX14462.1 322 GD18179 [Drosophila simulans]
GI:442621178 RefSeq XP_001981761.1 322 GG12226 [Drosophila erecta]
GI:442621178 RefSeq XP_002041287.1 322 GM10226 [Drosophila sechellia]
GI:442621178 RefSeq XP_002104959.1 322 GD18179 [Drosophila simulans]