Gene/Proteome Database (LMPD)

LMPD ID
LMP009116
Gene ID
2768720
Species
Drosophila melanogaster (Drosophila)
Gene Name
CG33503 gene product from transcript CG33503-RA
Gene Symbol
Cyp12d1-d
Synonyms
['12d1', '12D1', 'CG18239', 'CG18240', 'CG33503', 'CT26082', 'Cyp 12d1', 'Cyp12d1', 'CYP12D1', 'Cyp12d2', 'Dmel\CG33503']
Chromosome
2R
Map Location
47D4-47D4

Proteins

Cyp12d1-d
Refseq ID NP_995812
Protein GI 45552577
UniProt ID Q7KR10
mRNA ID NM_206090
Length 521
RefSeq Status REVIEWED
MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ

Gene Information

Entrez Gene ID
2768720
Gene Name
CG33503 gene product from transcript CG33503-RA
Gene Symbol
Cyp12d1-d
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016020 IEA:UniProtKB-KW C membrane
GO:0005739 ISS:UniProtKB C mitochondrion
GO:0030342 ISS:UniProtKB F 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
GO:0020037 IEA:InterPro F heme binding
GO:0005506 IEA:InterPro F iron ion binding
GO:0004497 IEA:UniProtKB-KW F monooxygenase activity
GO:0016705 IEA:InterPro F oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0055114 ISS:UniProtKB P oxidation-reduction process
GO:0046680 IMP:FlyBase P response to DDT
GO:0017085 IMP:FlyBase P response to insecticide

Domain Information

InterPro Annotations

Accession Description
IPR001128 Cytochrome P450
IPR017972 Cytochrome P450, conserved site
IPR002401 Cytochrome P450, E-class, group I

UniProt Annotations

Entry Information

Gene Name
CG33503 gene product from transcript CG33503-RA
Protein Entry
Q7KR10_DROME
UniProt ID
Q7KR10
Species
Drosophila

Comments

Comment Type Description
Catalytic Activity RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.
Cofactor Name=heme; Xref=ChEBI:CHEBI:30413; Evidence= ;
Developmental Stage Only expressed in adults. Expression varies in DDT resistant strains (Wisconsin, 91-R and Hikone-R).
Sequence Caution Sequence=AAL28963.1; Type=Erroneous initiation; Evidence= ;
Similarity Belongs to the cytochrome P450 family.
Subcellular Location Mitochondrion membrane .

Identical and Related Proteins

Unique RefSeq proteins for LMP009116 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
45552577 RefSeq NP_995812 521 Cyp12d1-d

Identical Sequences to LMP009116 proteins

Reference Database Accession Length Protein Name
GI:45552577 GenBank ABY20521.1 521 LP12934p [Drosophila melanogaster]
GI:45552577 gnl FlyBase 521 Cyp12d1-d [Drosophila melanogaster]
GI:45552577 SwissProt Q7KR10.1 521 RecName: Full=Probable cytochrome P450 12d1 distal, mitochondrial; AltName: Full=CYPXIID1; Flags: Precursor [Drosophila melanogaster]

Related Sequences to LMP009116 proteins

Reference Database Accession Length Protein Name
GI:45552577 GenBank AAL89789.1 521 CYP12D1 protein [Drosophila melanogaster]
GI:45552577 gnl FlyBase 521 Cyp12d1-p, isoform A [Drosophila melanogaster]
GI:45552577 gnl FlyBase 521 Cyp12d1-p, isoform B [Drosophila melanogaster]
GI:45552577 RefSeq NP_610635.4 521 Cyp12d1-p, isoform A [Drosophila melanogaster]
GI:45552577 RefSeq NP_001286304.1 521 Cyp12d1-p, isoform B [Drosophila melanogaster]
GI:45552577 SwissProt P82712.3 521 RecName: Full=Probable cytochrome P450 12d1 proximal, mitochondrial; AltName: Full=CYPXIID1; Flags: Precursor [Drosophila melanogaster]