Gene/Proteome Database (LMPD)

LMPD ID
LMP009118
Gene ID
31623
Species
Drosophila melanogaster (Drosophila)
Gene Name
xiantuan
Gene Symbol
xit
Synonyms
CG4542; Dalg8; Dmel\CG4542
Alternate Names
CG4542-PA; xiantuan; xit-PA
Chromosome
X
Map Location
6D3-6D3
EC Number
2.4.1.265

Proteins

xiantuan
Refseq ID NP_572355
Protein GI 18858153
UniProt ID Q9W3V8
mRNA ID NM_132127
Length 511
RefSeq Status REVIEWED
MKDLFWHLVGIATGLKILLIPAYHSTDFEVHRNWLAITHSLPLNQWYVDATSEWTLDYPPFFAYFEWLLSQVAKYVDPRMLVVDNLNYESKATVYFQRLSVIVTDLVYVLGVRSCLGSLGLGRDTQQFFAASMLLLLNVGLIFVDHIHFQYNGLLFGILLLSIGSLIRQRFLWSAFAFAVLLNFKHIFLYMAPAFGVYLLRFYCLEQASVVSAVGAVVKLLVVGLTPFAVSFGPFWQQLPQVLSRLFPFKRGLTHAYWAPNFWALYNAADKLAAGVLKVQDGGASTTSGLVQEVRHSVLPAITPPVTFALTALFMLPILVKLFRSAKKQSPLVFLRAVVLCGCSSFVFGWHVHEKAILMVLLPLCLLTLVNREDARYAYVLGIAGYFSLFPLLFDADLYIPRYSLYMSYVAMMYGQLYRIFPGFRGFHTLEWLYMLGFMAIPLYEHLLSFLLHLDQRLPFLPLLLTSVYSALGVLYFFGAYYLYALGISWGKVPIASSTSAAAVKRKRKTK

Gene Information

Entrez Gene ID
31623
Gene Name
xiantuan
Gene Symbol
xit
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IDA:FlyBase C endoplasmic reticulum
GO:0005789 IEA:InterPro C endoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016758 IEA:InterPro F transferase activity, transferring hexosyl groups
GO:0003384 IMP:FlyBase P apical constriction involved in gastrulation
GO:0007377 IMP:FlyBase P germ-band extension
GO:0006486 IMP:FlyBase P protein glycosylation

KEGG Pathway Links

KEGG Pathway ID Description
dme01100 Metabolic pathways
dme00510 N-Glycan biosynthesis
ko00510 N-Glycan biosynthesis
dme_M00055 N-glycan precursor biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR004856 Glycosyl transferase, ALG6/ALG8

UniProt Annotations

Entry Information

Gene Name
xiantuan
Protein Entry
ALG8_DROME
UniProt ID
Q9W3V8
Species
Drosophila

Comments

Comment Type Description
Catalytic Activity Dolichyl beta-D-glucosyl phosphate + D-Glc- alpha-(1->3)-D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha- (1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->2)- D-Man-alpha-(1->6))-D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D- GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = D-Glc-alpha- (1->3)-D-Glc-alpha-(1->3)-D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D- Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man- alpha-(1->2)-D-Man-alpha-(1->6))-D-Man-alpha-(1->6)]-D-Man-beta- (1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.
Function Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity). {ECO:0000250}.
Pathway Protein modification; protein glycosylation.
Similarity Belongs to the ALG6/ALG8 glucosyltransferase family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP009118 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
18858153 RefSeq NP_572355 511 xiantuan

Identical Sequences to LMP009118 proteins

Reference Database Accession Length Protein Name
GI:18858153 GenBank AAL39807.1 511 LD44072p [Drosophila melanogaster]
GI:18858153 GenBank ACL86062.1 511 CG4542-PA, partial [synthetic construct]
GI:18858153 GenBank ACL90836.1 511 CG4542-PA [synthetic construct]
GI:18858153 gnl FlyBase 511 xiantuan [Drosophila melanogaster]
GI:18858153 SwissProt Q9W3V8.1 511 RecName: Full=Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase; Short=Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase; AltName: Full=Asparagine-linked glycosylation protein 8 homolog; AltName: Full=Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase [Drosophila melanogaster]

Related Sequences to LMP009118 proteins

Reference Database Accession Length Protein Name
GI:18858153 GenBank EDV47415.1 513 GG19614 [Drosophila erecta]
GI:18858153 GenBank EDW52877.1 511 GM12534 [Drosophila sechellia]
GI:18858153 GenBank EDX01053.1 506 GE16775 [Drosophila yakuba]
GI:18858153 RefSeq XP_001978488.1 513 GG19614 [Drosophila erecta]
GI:18858153 RefSeq XP_002036718.1 511 GM12534 [Drosophila sechellia]
GI:18858153 RefSeq XP_002099945.1 506 GE16775 [Drosophila yakuba]