Gene/Proteome Database (LMPD)

LMPD ID
LMP009125
Gene ID
35255
Species
Drosophila melanogaster (Drosophila)
Gene Name
CG10268 gene product from transcript CG10268-RA
Gene Symbol
CG10268
Synonyms
BcDNA:SD12705; Dmel\CG10268
Alternate Names
CG10268; CG10268-PA
Chromosome
2L
Map Location
37F2-37F2
EC Number
2.7.4.2

Proteins

CG10268
Refseq ID NP_609992
Protein GI 24585296
UniProt ID Q9VIT2
mRNA ID NM_136148
Length 189
RefSeq Status REVIEWED
MMKIVLISGKRKCGKDYISERLQRRLGSRSCIVRISEPIKSEWARKLQLDLDALLGDGPYKEKYRRDMIVWSDEVRAQDYGYFCRVAMEEALSRQQTPYILVSDVRRKNDIRWFRETYGPERVITLRLTSRPETRSARGWTFTAGIDDVPSECDLDDLADGFDVVLANDEELDQEAIDILLDRLQLQYR

Gene Information

Entrez Gene ID
35255
Gene Name
CG10268 gene product from transcript CG10268-RA
Gene Symbol
CG10268
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:InterPro C cytoplasm
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0004631 IEA:UniProtKB-EC F phosphomevalonate kinase activity
GO:0006695 IEA:UniProtKB-KW P cholesterol biosynthetic process
GO:0019287 IEA:UniProtKB-UniPathway P isopentenyl diphosphate biosynthetic process, mevalonate pathway
GO:0008299 IC:FlyBase P isoprenoid biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
dme_M00095 C5 isoprenoid biosynthesis, mevalonate pathway
dme04146 Peroxisome
dme00900 Terpenoid backbone biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
6226905 Activation of gene expression by SREBF (SREBP)

Domain Information

InterPro Annotations

Accession Description
IPR005919 Higher eukaryotic phosphomevalonate kinase
IPR027417 P-loop containing nucleoside triphosphate hydrolase

UniProt Annotations

Entry Information

Gene Name
CG10268 gene product from transcript CG10268-RA
Protein Entry
PMVK_DROME
UniProt ID
Q9VIT2
Species
Drosophila

Comments

Comment Type Description
Catalytic Activity ATP + (R)-5-phosphomevalonate = ADP + (R)-5- diphosphomevalonate.
Pathway Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 2/3.

Identical and Related Proteins

Unique RefSeq proteins for LMP009125 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
24585296 RefSeq NP_609992 189 CG10268

Identical Sequences to LMP009125 proteins

Reference Database Accession Length Protein Name
GI:24585296 GenBank ACH92509.1 189 FI09828p [Drosophila melanogaster]
GI:24585296 gnl FlyBase 189 CG10268 [Drosophila melanogaster]
GI:24585296 SwissProt Q9VIT2.1 189 RecName: Full=Probable phosphomevalonate kinase; Short=PMKase [Drosophila melanogaster]

Related Sequences to LMP009125 proteins

Reference Database Accession Length Protein Name
GI:24585296 GenBank AAM51057.1 189 SD12705p [Drosophila melanogaster]
GI:24585296 GenBank EDW55791.1 189 GM16997 [Drosophila sechellia]
GI:24585296 GenBank EDX05545.1 189 GD21744 [Drosophila simulans]
GI:24585296 RefSeq XP_002039145.1 189 GM16997 [Drosophila sechellia]
GI:24585296 RefSeq XP_002045694.1 189 GM22069 [Drosophila sechellia]
GI:24585296 RefSeq XP_002079960.1 189 GD21744 [Drosophila simulans]