Gene/Proteome Database (LMPD)
Proteins
CG12034 | |
---|---|
Refseq ID | NP_647790 |
Protein GI | 21357231 |
UniProt ID | Q9VZS6 |
mRNA ID | NM_139533 |
Length | 442 |
RefSeq Status | REVIEWED |
MLLLELNILTLNIWGIPYVSSDRRPRIDAICKELASGKYDIVSLQEVWAQEDSELLQKGTEAVLPHSHYFHSGVMGAGLLVLSKYPILGTLFHAWSVNGYFHRIQHADWFGGKGVGLCRILVGGQMVHLYNAHLHAEYDNANDEYKTHRVIQAFDTAQFIEATRGNSALQILAGDLNAQPQDISYKVLLYTSKMLDSCDSDSFRTNECEHNSYTSKQARERNPLGIRIDHIFVRGGDHVNAEIAEYKLPFPERVPGEKFSFSDHEAVMAKLKLFKLEPRSEEPVATIEVNCLVEDGETCSVREVGAGDALTGEDDQSSQHQPEIQCNGSSTSIQSMPAARTAALLEALALCDASLLQLNTDRILYYSAATFLFVLLVLLVEFTAPVGMRTIFLLLKFIVFGVILFCVFMASIWNYMERNGVLQGKKSMEVMLHHAQKYEYFY |
Gene Information
Entrez Gene ID
Gene Name
CG12034 gene product from transcript CG12034-RA
Gene Symbol
Species
Drosophila melanogaster
Gene Ontology (GO Annotations)
GO ID | Source | Type | Description |
---|---|---|---|
GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
GO:0046872 | IEA:UniProtKB-KW | F | metal ion binding |
GO:0004767 | IEA:UniProtKB-EC | F | sphingomyelin phosphodiesterase activity |
GO:0006665 | IEA:UniProtKB-UniPathway | P | sphingolipid metabolic process |
KEGG Pathway Links
REACTOME Pathway Links
Domain Information
InterPro Annotations
Accession | Description |
---|---|
IPR005135 | Endonuclease/exonuclease/phosphatase |
UniProt Annotations
Entry Information
Gene Name
CG12034 gene product from transcript CG12034-RA
Protein Entry
NSMA_DROME
UniProt ID
Species
Drosophila
Comments
Comment Type | Description |
---|---|
Catalytic Activity | Sphingomyelin + H(2)O = N-acylsphingosine + phosphocholine. |
Interaction | Q7JV09:jp; NbExp=1; IntAct=EBI-125601, EBI-141560; Q9V447:Kr-h2; NbExp=1; IntAct=EBI-125601, EBI-135893; |
Pathway | Lipid metabolism; sphingolipid metabolism. |
Similarity | Belongs to the neutral sphingomyelinase family. {ECO:0000305}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP009156 (as displayed in Record Overview)
Identical Sequences to LMP009156 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:21357231 | GenBank | AAK93138.1 | 442 | LD24865p [Drosophila melanogaster] |
GI:21357231 | GenBank | ACL85016.1 | 442 | CG12034-PA, partial [synthetic construct] |
GI:21357231 | GenBank | ACL89931.1 | 442 | CG12034-PA [synthetic construct] |
GI:21357231 | gnl | FlyBase | 442 | CG12034 [Drosophila melanogaster] |
GI:21357231 | SwissProt | Q9VZS6.2 | 442 | RecName: Full=Putative neutral sphingomyelinase [Drosophila melanogaster] |
Related Sequences to LMP009156 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:21357231 | GenBank | ACK57212.1 | 321 | CG12034-like protein, partial [Drosophila affinis] |
GI:21357231 | GenBank | JAB99762.1 | 451 | Putative neutral sphingomyelinase, partial [Ceratitis capitata] |
GI:21357231 | GenBank | JAD02310.1 | 417 | hypothetical protein g.23281 [Bactrocera cucurbitae] |
GI:21357231 | gnl | WGS:AADE | 453 | GA11353 [Drosophila pseudoobscura pseudoobscura] |
GI:21357231 | RefSeq | XP_001352679.1 | 453 | GA11353 [Drosophila pseudoobscura pseudoobscura] |
GI:21357231 | RefSeq | XP_004526817.1 | 422 | PREDICTED: putative neutral sphingomyelinase-like [Ceratitis capitata] |