Gene/Proteome Database (LMPD)
LMPD ID
LMP009158
Gene ID
Species
Drosophila melanogaster (Drosophila)
Gene Name
yolkless
Gene Symbol
Synonyms
CG1372; CT3114; Dmel\CG1372; DmYPR; fs(1)148; fs(1)5; fs(1)A148; fs(1)K184; fs(1)L186; fs(1)L193; fs(1)L196; fs(1)L211; fs(1)M205; fs(1)M25; fs(1)yl; fs(1)yolkless; LR13; Yl; YL
Alternate Names
CG1372-PA; CG1372-PB; Dm yolkless; YP receptor; yl-PA; yl-PB; yolkless
Chromosome
X
Map Location
12E3-12E3
Proteins
| yolkless, isoform A | |
|---|---|
| Refseq ID | NP_511151 |
| Protein GI | 24641935 |
| UniProt ID | P98163 |
| mRNA ID | NM_078596 |
| Length | 1937 |
| RefSeq Status | REVIEWED |
| MCQAEHQVHPSEQRIRVESPKMTASRRGFNLTSQTRAHPSSGGSTSSRYGNCQRTHLIINGRHVAISLLLLVGLCGGTAAGTPGSADTRCDAGQFQCRDGGCILQAKMCDGRGDCKDSSDELDCDYRLCRPPHWFPCAQPHGACLAAELMCNGIDNCPGGEDELNCPVRPGFRFGDTAHRMRSCSKYEFMCQQDRTCIPIDFMCDGRPDCTDKSDEVAGCKQAEITCPGEGHLCANGRCLRRKQWVCDGVDDCGDGSDERGCLNLCEPQKGKFLCRNRETCLTLSEVCDGHSDCSDGSDETDLCHSKPDCDAKKCALGAKCHMMPASGAECFCPKGFRLAKFEDKCEDVDECKEQDDLCSQGCENTSGGYRCVCDAGYLLDKDNRTCRAVVYGSKEQQPLLLYTTQMTIMGMHLREDNVRNHVYQVAGNLSKVIGVAYDGSHIYWTNIQNEAESIVKANGDGSNAEILLTSGLDAPEDLAVDWLTQNIYFSDNIMRHIAVCSNDGLNCAVLVTQDVHQPRSLAVWPQKGLMFWTDWGEKPMIGRASMDGSRSRPIVSDNIEWPNGIALDMHQQRIYWVDAKLGSVQTVRPDGTGRRTVLDGMLKHPYGLAIFEDQLYWSDWATKSVHACHKFSGKDHRILAKDRTIYAVHIYHPAKQPNSPHGCENATCSHLCLLAEPEIGGHSCACPDGMRLAPDHRRCMLMEKRQRLFIGLGQVLLEIEHTAFGRHQVSKSYTLPCLINEMVYNRINGSLIIADNDQRLILEFQPESHESNVLVRSNLGNVSALAFDHLSRNLYWADTERAVIEVLSLQTRHRALIRFFPGQEVPIGLTVMPAEGYLYVVLKAKRHSHIDKIPLSGKGEQVHVFEDDLGDDDIKLVTDYETQTIFWSDSDLGRISYSNYRVPHSQIFRGKLRRPYSLAMVHHDLFWNELGTPRIYWTHKSNMGPRKVIDIMEKDDPAAIMPYVPVATPNGIPLAASSPVGQESHPCQQQNGGCSHICVGEGPYHSICLCPAGFVYRDAGNRTCVEALDCEFRCHSGECLTMNHRCNGRRDCVDNSDEMNCDEEHRRKPKVLCSPNQFACHSGEQCVDKERRCDNRKDCHDHSDEQHCEKFDKSKKCHVHQHGCDNGKCVDSSLVCDGTNDCGDNSDELLCEATSRCEPGMFQCGSGSCIAGSWECDGRIDCSDGSDEHDKCVHRSCPPDMQRCLLGQCLDRSLVCDGHNDCGDKSDELNCGTDSSTMNISCAEDQYQCTSNLKICLPSTVRCNGTTECPRGEDEADCGDVCSIYEFKCRSGRECIRREFRCDGQKDCGDGSDELSCELEKGHHNQSQIQPWSTSSRSCRPHLFDCQDGECVDLSRVCNNFPDCTNGHDEGPKCATACRSASGRQVCQHKCRATPAGAVCSCFDGYRLDADQKSCLDIDECQEQQPCAQLCENTLGGYQCQCHADFMLRQDRVSCKSLQSGATLLFSSFNEVRNLSEQPVMLNVAWSANDSRITGFDLAMHRQMGYFSAEDEGIVYQIDLQTKVIVRALGLPAPTKLSVDWVTGNVYVLSGAQEIQACSFVGRMCGRIVHVKSPRHVKHLAVDGYHARIFYIVIRTEGYGQTSSEIHMARLDGSRRDMLLQRSESFMTALTTDPHQQLLYFVDQHMRTLERISYRLKTGPMRRPEIMLQKSNALMHPSGLSVYENNAFIVNLGSVEAVQCALYGSRICHKISINVLNAQDIVVAGRSRQPQKASHPCAHAHCHGLCLQADYGYECMCGNRLVAEGERCPHGSGNEVAVLGAVNSLELEHEHEQNGHFHWLMALFVLAAGSLIAGLGYMYYQYRQRGHTDLNINMHFQNPLATLGGTKAFLEHERAEAGVGFTTETGTVSSRGSNDTFTTTSATSSFAAQQFSVPNALQRLLRPRQSASGDPMAQELLLESPSRVSSDGGQMAVEDM | |
| yolkless, isoform B | |
|---|---|
| Refseq ID | NP_996433 |
| Protein GI | 45555120 |
| UniProt ID | P98163 |
| mRNA ID | NM_206710 |
| Length | 1984 |
| RefSeq Status | REVIEWED |
| MCQAEHQVHPSEQRIRVESPKMTASRRGFNLTSQTRAHPSSGGSTSSRYGNCQRTHLIINGRHVAISLLLLVGLCGGTAAGTPGSADTRCDAGQFQCRDGGCILQAKMCDGRGDCKDSSDELDCDYRLCRPPHWFPCAQPHGACLAAELMCNGIDNCPGGEDELNCPVRPGFRFGDTAHRMRSCSKYEFMCQQDRTCIPIDFMCDGRPDCTDKSDEVAGCKQAEITCPGEGHLCANGRCLRRKQWVCDGVDDCGDGSDERGCLNLCEPQKGKFLCRNRETCLTLSEVCDGHSDCSDGSDETDLCHSKPDCDAKKCALGAKCHMMPASGAECFCPKGFRLAKFEDKCEDVDECKEQDDLCSQGCENTSGGYRCVCDAGYLLDKDNRTCRAVVYGSKEQQPLLLYTTQMTIMGMHLREDNVRNHVYQVAGNLSKVIGVAYDGSHIYWTNIQNEAESIVKANGDGSNAEILLTSGLDAPEDLAVDWLTQNIYFSDNIMRHIAVCSNDGLNCAVLVTQDVHQPRSLAVWPQKGLMFWTDWGEKPMIGRASMDGSRSRPIVSDNIEWPNGIALDMHQQRIYWVDAKLGSVQTVRPDGTGRRTVLDGMLKHPYGLAIFEDQLYWSDWATKSVHACHKFSGKDHRILAKDRTIYAVHIYHPAKQPNSPHGCENATCSHLCLLAEPEIGGHSCACPDGMRLAPDHRRCMLMEKRQRLFIGLGQVLLEIEHTAFGRHQVSKSYTLPCLINEMVYNRINGSLIIADNDQRLILEFQPESHESNVLVRSNLGNVSALAFDHLSRNLYWADTERAVIEVLSLQTRHRALIRFFPGQEVPIGLTVMPAEGYLYVVLKAKRHSHIDKIPLSGKGEQVHVFEDDLGDDDIKLVTDYETQTIFWSDSDLGRISYSNYRVPHSQIFRGKLRRPYSLAMVHHDLFWNELGTPRIYWTHKSNMGPRKVIDIMEKDDPAAIMPYVPVATPNGIPLAASSPVGQESHPCQQQNGGCSHICVGEGPYHSICLCPAGFVYRDAGNRTCVEALDCEFRCHSGECLTMNHRCNGRRDCVDNSDEMNCDEEHRRKPKVLCSPNQFACHSGEQCVDKERRCDNRKDCHDHSDEQHCEKFDKSKKCHVHQHGCDNGKCVDSSLVCDGTNDCGDNSDELLCEATSRCEPGMFQCGSGSCIAGSWECDGRIDCSDGSDEHDKCVHRSCPPDMQRCLLGQCLDRSLVCDGHNDCGDKSDELNCGTDSSTMNISCAEDQYQCTSNLKICLPSTVRCNGTTECPRGEDEADCGDVCSIYEFKCRSGRECIRREFRCDGQKDCGDGSDELSCELEKGHHNQSQIQPWSTSSRSCRPHLFDCQDGECVDLSRVCNNFPDCTNGHDEGPKCATACRSASGRQVCQHKCRATPAGAVCSCFDGYRLDADQKSCLDIDECQEQQPCAQLCENTLGGYQCQCHADFMLRQDRVSCKSLQSGATLLFSSFNEVRNLSEQPVMLNVAWSANDSRITGFDLAMHRQMGYFSAEDEGIVYQIDLQTKVIVRALGLPAPTKLSVDWVTGNVYVLSGAQEIQACSFVGRMCGRIVHVKSPRHVKHLAVDGYHARIFYIVIRTEGYGQTSSEIHMARLDGSRRDMLLQRSESFMTALTTDPHQQLLYFVDQHMRTLERISYRLKTGPMRRPEIMLQKSNALMHPSGLSVYENNAFIVNLGSVEAVQCALYGSRICHKISINVLNAQDIVVAGRSRQPQKASHPCAHAHCHGLCLQADYGYECMCGNRLVAEGERCPHGSGNEVAVLGAVNSLELEHEHEQNGHFHWLMALFVLAAGSLIAGLGYMYYQYRQRGHTDLNINMHFQNPLATLGGTKAFLEHERAEAGVGFTTETGTVSSRGSNDTFTTTSATSSFAAQQFSVPNALQRLLRPRQSASGDPMAQELLLESPSRESKLHALDGGGAGGDGDGGRGVGRQVPDILVADMDDDAAKSAGQFGGNYAGNDANARFVS | |
Gene Information
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0030135 | IDA:FlyBase | C | coated vesicle |
| GO:0031410 | IDA:FlyBase | C | cytoplasmic vesicle |
| GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
| GO:0005886 | IEA:UniProtKB-KW | C | plasma membrane |
| GO:0005509 | IEA:InterPro | F | calcium ion binding |
| GO:0008196 | ISS:FlyBase | F | vitellogenin receptor activity |
| GO:0048477 | NAS:FlyBase | P | oogenesis |
| GO:0006898 | ISS:GOC | P | receptor-mediated endocytosis |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR026823 | Complement Clr-like EGF domain |
| IPR001881 | EGF-like calcium-binding domain |
| IPR018097 | EGF-like calcium-binding, conserved site |
| IPR013032 | EGF-like, conserved site |
| IPR000152 | EGF-type aspartate/asparagine hydroxylation site |
| IPR000742 | Epidermal growth factor-like domain |
| IPR000033 | LDLR class B repeat |
| IPR002172 | Low-density lipoprotein (LDL) receptor class A repeat |
| IPR023415 | Low-density lipoprotein (LDL) receptor class A, conserved site |
| IPR011042 | Six-bladed beta-propeller, TolB-like |
UniProt Annotations
Entry Information
Comments
| Comment Type | Description |
|---|---|
| Alternative Products | Event=Alternative splicing; Named isoforms=2; Name=B; IsoId=P98163-1; Sequence=Displayed; Note=No experimental confirmation available.; Name=A; IsoId=P98163-2; Sequence=VSP_010300; |
| Function | Involved in uptake of vitellogenin by endocytosis. |
| Similarity | Contains 11 LDL-receptor class B repeats. {ECO:0000255|PROSITE-ProRule:PRU00461}. |
| Similarity | Contains 13 LDL-receptor class A domains. {ECO:0000255|PROSITE-ProRule:PRU00124}. |
| Similarity | Contains 7 EGF-like domains. {ECO:0000255|PROSITE- ProRule:PRU00076}. |
| Subcellular Location | Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Tissue Specificity | Ovary. |
Identical and Related Proteins
Unique RefSeq proteins for LMP009158 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 24641935 | RefSeq | NP_511151 | 1937 | yolkless, isoform A |
| 45555120 | RefSeq | NP_996433 | 1984 | yolkless, isoform B |
Identical Sequences to LMP009158 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:24641935 | gnl | FlyBase | 1937 | yolkless, isoform A [Drosophila melanogaster] |
| GI:45555120 | gnl | FlyBase | 1984 | yolkless, isoform B [Drosophila melanogaster] |
| GI:45555120 | SwissProt | P98163.2 | 1984 | RecName: Full=Putative vitellogenin receptor; AltName: Full=Protein yolkless; Short=YL; Flags: Precursor [Drosophila melanogaster] |
Related Sequences to LMP009158 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:45555120 | GenBank | AAB60217.1 | 1984 | vitellogenin receptor [Drosophila melanogaster] |
| GI:24641935 | GenBank | AAB60217.1 | 1984 | vitellogenin receptor [Drosophila melanogaster] |
| GI:24641935 | GenBank | AAO39481.1 | 1937 | RE59172p [Drosophila melanogaster] |
| GI:45555120 | GenBank | AAO39481.1 | 1937 | RE59172p [Drosophila melanogaster] |
| GI:45555120 | gnl | FlyBase | 1937 | yolkless, isoform A [Drosophila melanogaster] |
| GI:24641935 | gnl | FlyBase | 1984 | yolkless, isoform B [Drosophila melanogaster] |
| GI:45555120 | PRF | - | 1984 | vitellogenin receptor [Drosophila melanogaster] |
| GI:24641935 | PRF | - | 1984 | vitellogenin receptor [Drosophila melanogaster] |
| GI:45555120 | RefSeq | NP_511151.2 | 1937 | yolkless, isoform A [Drosophila melanogaster] |
| GI:24641935 | RefSeq | NP_996433.1 | 1984 | yolkless, isoform B [Drosophila melanogaster] |
| GI:45555120 | RefSeq | XP_002042769.1 | 1977 | GM17661 [Drosophila sechellia] |
| GI:24641935 | SwissProt | P98163.2 | 1984 | RecName: Full=Putative vitellogenin receptor; AltName: Full=Protein yolkless; Short=YL; Flags: Precursor [Drosophila melanogaster] |