Gene/Proteome Database (LMPD)
LMPD ID
LMP009655
Gene ID
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
1-acyl-sn-glycerol-3-phosphate acyltransferase 3
Gene Symbol
Synonyms
F11M15.12; F11M15_12; LPAT3; lysophosphatidyl acyltransferase 3
Alternate Names
1-acyl-sn-glycerol-3-phosphate acyltransferase 3
Chromosome
1
EC Number
2.3.1.51
Summary
ACYL-COA:1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE, PUTATIVE SIMILAR TO ACYL-COA:1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE GI:4583544 FROM [BRASSICA NAPUS]
Orthologs
Proteins
| 1-acyl-sn-glycerol-3-phosphate acyltransferase 3 | |
|---|---|
| Refseq ID | NP_175537 |
| Protein GI | 15223789 |
| UniProt ID | Q9SYC8 |
| mRNA ID | NM_104004 |
| Length | 376 |
| RefSeq Status | REVIEWED |
| MKIPAALVFIPVGVLFLISGLIVNIIQLVFFIIVRPFSRSLYRRINKNVAELLWLQLIWLFDWWACIKINLYVDAETLELIGKEHALVLSNHRSDIDWLIGWVMAQRVGCLGSSLAIMKKEAKYLPIIGWSMWFSDYIFLERSWAKDENTLKAGFKRLEDFPMTFWLALFVEGTRFTQEKLEAAQEYASIRSLPSPRNVLIPRTKGFVSAVSEIRSFVPAIYDCTLTVHNNQPTPTLLRMFSGQSSEINLQMRRHKMSELPETDDGIAQWCQDLFITKDAQLEKYFTKDVFSDLEVHQINRPIKPLIVVIIWLGFLVFGGFKLLQWLSIVASWKIILLFVFFLVIATITMQILIQSSESQRSTPAKRPLQEQLISA | |
Gene Information
Entrez Gene ID
Gene Name
1-acyl-sn-glycerol-3-phosphate acyltransferase 3
Gene Symbol
Species
Arabidopsis thaliana
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
| GO:0003841 | IDA:TAIR | F | 1-acylglycerol-3-phosphate O-acyltransferase activity |
| GO:0016024 | IEA:UniProtKB-UniPathway | P | CDP-diacylglycerol biosynthetic process |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| ath00561 | Glycerolipid metabolism |
| ath00564 | Glycerophospholipid metabolism |
| ath01100 | Metabolic pathways |
REACTOME Pathway Links
| REACTOME Pathway ID | Description |
|---|---|
| 6253800 | Synthesis of PA |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR002123 | Phospholipid/glycerol acyltransferase |
UniProt Annotations
Entry Information
Gene Name
1-acyl-sn-glycerol-3-phosphate acyltransferase 3
Protein Entry
LPAT3_ARATH
UniProt ID
Species
Arabidopsis
Comments
| Comment Type | Description |
|---|---|
| Catalytic Activity | Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate. {ECO:0000269|PubMed:15772283}. |
| Domain | The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. {ECO:0000250}. |
| Function | Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position. Has preference for C-18-CoA substrates compared to C-16-CoA substrates. |
| Pathway | Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3. |
| Sequence Caution | Sequence=BX813937; Type=Erroneous termination; Positions=325; Note=Translated as Gln.; Evidence={ECO:0000305}; |
| Similarity | Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. {ECO:0000305}. |
| Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Tissue Specificity | Predominantly expressed in pollen. {ECO:0000269|PubMed:15772283}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP009655 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 15223789 | RefSeq | NP_175537 | 376 | 1-acyl-sn-glycerol-3-phosphate acyltransferase 3 |
Identical Sequences to LMP009655 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:15223789 | GenBank | AAD30638.1 | 376 | Putative acyl-CoA:1-acylglycerol-3-phosphate acyltransferase [Arabidopsis thaliana] |
| GI:15223789 | GenBank | ACX06337.1 | 376 | Sequence 29844 from patent US 7569389 |
| GI:15223789 | GenBank | AEE32642.1 | 376 | 1-acyl-sn-glycerol-3-phosphate acyltransferase 3 [Arabidopsis thaliana] |
| GI:15223789 | SwissProt | Q9SYC8.1 | 376 | RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase 3; AltName: Full=Lysophosphatidyl acyltransferase 3 [Arabidopsis thaliana] |
Related Sequences to LMP009655 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:15223789 | GenBank | EFH70566.1 | 376 | hypothetical protein ARALYDRAFT_474240 [Arabidopsis lyrata subsp. lyrata] |
| GI:15223789 | GenBank | EOA37613.1 | 376 | hypothetical protein CARUB_v10012002mg [Capsella rubella] |
| GI:15223789 | RefSeq | XP_002894307.1 | 376 | hypothetical protein ARALYDRAFT_474240 [Arabidopsis lyrata subsp. lyrata] |
| GI:15223789 | RefSeq | XP_002894308.1 | 504 | hypothetical protein ARALYDRAFT_892094 [Arabidopsis lyrata subsp. lyrata] |
| GI:15223789 | RefSeq | XP_006304715.1 | 376 | hypothetical protein CARUB_v10012002mg [Capsella rubella] |
| GI:15223789 | RefSeq | XP_010461958.1 | 376 | PREDICTED: 1-acyl-sn-glycerol-3-phosphate acyltransferase 3 [Camelina sativa] |