Gene/Proteome Database (LMPD)

LMPD ID
LMP009677
Gene ID
841998
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
branched-chain alpha-keto acid decarboxylase E1 beta subunit
Gene Symbol
BCDH BETA1
Synonyms
branched-chain alpha-keto acid decarboxylase E1 beta subunit; BRANCHED-CHAIN ALPHA-KETO ACID DECARBOXYLASE E1 BETA SUBUNIT; T5A14.9; T5A14_9
Alternate Names
branched-chain alpha-keto acid decarboxylase E1 beta subunit
Chromosome
1
EC Number
1.2.4.4
Summary
branched-chain alpha-keto acid decarboxylase E1 beta
Orthologs
View orthologs and multiple alignments for BCDH BETA1

Proteins

branched-chain alpha-keto acid decarboxylase E1 beta subunit
Refseq ID NP_175947
Protein GI 15222731
UniProt ID Q9SAV3
mRNA ID NM_104426
Length 352
RefSeq Status REVIEWED
MAALLGRSCRKLSFPSLSHGARRVSTETGKPLNLYSAINQALHIALDTDPRSYVFGEDVGFGGVFRCTTGLAERFGKNRVFNTPLCEQGIVGFGIGLAAMGNRAIVEIQFADYIYPAFDQIVNEAAKFRYRSGNQFNCGGLTIRAPYGAVGHGGHYHSQSPEAFFCHVPGIKVVIPRSPREAKGLLLSCIRDPNPVVFFEPKWLYRQAVEEVPEHDYMIPLSEAEVIREGNDITLVGWGAQLTVMEQACLDAEKEGISCELIDLKTLLPWDKETVEASVKKTGRLLISHEAPVTGGFGAEISATILERCFLKLEAPVSRVCGLDTPFPLVFEPFYMPTKNKILDAIKSTVNY

Gene Information

Entrez Gene ID
841998
Gene Name
branched-chain alpha-keto acid decarboxylase E1 beta subunit
Gene Symbol
BCDH BETA1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IEA:UniProtKB-KW C mitochondrion
GO:0003863 IEA:UniProtKB-EC F 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity

KEGG Pathway Links

KEGG Pathway ID Description
ath01110 Biosynthesis of secondary metabolites
ath_M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA
ath01100 Metabolic pathways

REACTOME Pathway Links

REACTOME Pathway ID Description
6253683 Branched-chain amino acid catabolism

Domain Information

InterPro Annotations

Accession Description
IPR029061 Thiamin diphosphate-binding fold
IPR005476 Transketolase, C-terminal
IPR009014 Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II
IPR005475 Transketolase-like, pyrimidine-binding domain

UniProt Annotations

Entry Information

Gene Name
branched-chain alpha-keto acid decarboxylase E1 beta subunit
Protein Entry
ODBB1_ARATH
UniProt ID
Q9SAV3
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity 3-methyl-2-oxobutanoate + [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine = [dihydrolipoyllysine-residue (2- methylpropanoyl)transferase] S-(2- methylpropanoyl)dihydrolipoyllysine + CO(2).
Function The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). {ECO:0000250}.
Subcellular Location Mitochondrion matrix {ECO:0000250}.
Subunit Heterotetramer of alpha and beta chains. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP009677 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15222731 RefSeq NP_175947 352 branched-chain alpha-keto acid decarboxylase E1 beta subunit

Identical Sequences to LMP009677 proteins

Reference Database Accession Length Protein Name
GI:15222731 GenBank AAD10651.1 352 branched-chain alpha-keto acid decarboxylase E1 beta subunit [Arabidopsis thaliana]
GI:15222731 GenBank ABD59079.1 352 At1g55510 [Arabidopsis thaliana]
GI:15222731 GenBank AEE33256.1 352 branched-chain alpha-keto acid decarboxylase E1 beta subunit [Arabidopsis thaliana]
GI:15222731 GenBank AFX58133.1 352 Sequence 78 from patent US 8309323
GI:15222731 SwissProt Q9SAV3.1 352 RecName: Full=2-oxoisovalerate dehydrogenase subunit beta 1, mitochondrial; AltName: Full=Branched-chain alpha-keto acid dehydrogenase E1 component beta chain; Short=BCKDE1B; Short=BCKDH E1-beta; Flags: Precursor [Arabidopsis thaliana]

Related Sequences to LMP009677 proteins

Reference Database Accession Length Protein Name
GI:15222731 GenBank AAC64005.1 352 branched-chain alpha-keto acid decarboxylase E1 beta subunit [Arabidopsis thaliana]
GI:15222731 GenBank AAW00650.1 352 Sequence 14 from patent US 6773917
GI:15222731 GenBank AAW00670.1 352 Sequence 51 from patent US 6773917
GI:15222731 GenBank EFH68097.1 352 BCDH BETA1 [Arabidopsis lyrata subsp. lyrata]
GI:15222731 RefSeq XP_002891838.1 352 BCDH BETA1 [Arabidopsis lyrata subsp. lyrata]
GI:15222731 RefSeq XP_010501164.1 353 PREDICTED: 2-oxoisovalerate dehydrogenase subunit beta 1, mitochondrial [Camelina sativa]