Gene/Proteome Database (LMPD)
Proteins
| 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3 | |
|---|---|
| Refseq ID | NP_565998 |
| Protein GI | 18406234 |
| UniProt ID | A9X4U2 |
| mRNA ID | NM_129903 |
| Length | 561 |
| RefSeq Status | REVIEWED |
| MDEDSVHGDSHLKTCVVLGGRGFIGRSLVSRLLRLGNWTVRVADSGHTLHLDESDSLLEDALSSGRASYHCVDVRDKPQIVKVTEGSYVVFYMGATDLRSHDYFDCYKVIVQGTRNVISACRESGVRKLIYNSTADVVFDGSQPIRDGDESLRRPLKFQSMLTDFKAQAEALIKLANNRDGLLTCALRSSIVFGPGDTEFVPFLVNLAKSGYAKFILGSGENISDFTYSENVSHAHICAVKALDSQMEFVAGKEFFITNLKPVRFWDFVSHIVEGLGYPRPSIKLPVRLVLYVFSLLKWTHEKEGLGSNYDTAHQYALLASSTRTFNCNAAKKHLGYTPVVTLEDGIASTLQWFSRDLEKSDDTIIQSTADQLLGCGKVADILLWRNEKKTFVSFLVLNLFYYWFFFSGNTFTSSAAQLLFIFAVALYGVSFVPSKIFGFQVNKIPPWRFEISESAVRDLSSDIVVVWNQGVRSFKSLSSGGDWIKFFKIAGSLYLLKLIVSRSLAAFLFTVMSFSFTGFFIYEQYELELYHLARIFVECLTFIKRMVIPVSDASSKPMFM | |
Gene Information
Entrez Gene ID
Gene Name
3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3
Gene Symbol
Species
Arabidopsis thaliana
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005783 | IEA:UniProtKB-KW | C | endoplasmic reticulum |
| GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
| GO:0005886 | IDA:TAIR | C | plasma membrane |
| GO:0009506 | IDA:TAIR | C | plasmodesma |
| GO:0003854 | IEA:InterPro | F | 3-beta-hydroxy-delta5-steroid dehydrogenase activity |
| GO:0047012 | IEA:UniProtKB-EC | F | sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity |
| GO:0016126 | IEA:UniProtKB-KW | P | sterol biosynthetic process |
BIOCYC Pathway Links
| BIOCYC Pathway ID | Description |
|---|---|
| PWY66-341 | cholesterol biosynthesis I |
REACTOME Pathway Links
Domain Information
UniProt Annotations
Entry Information
Gene Name
3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3
Protein Entry
HSDD3_ARATH
UniProt ID
Species
Arabidopsis
Comments
| Comment Type | Description |
|---|---|
| Catalytic Activity | A 3-beta-hydroxysteroid-4-alpha-carboxylate + NAD(P)(+) = a 3-oxosteroid + CO(2) + NAD(P)H. |
| Pathway | Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 4/6. |
| Similarity | Belongs to the 3-beta-HSD family. {ECO:0000305}. |
| Similarity | Contains 1 reticulon domain. {ECO:0000255|PROSITE- ProRule:PRU00170}. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP009683 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 18406234 | RefSeq | NP_565998 | 561 | 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3 |
Identical Sequences to LMP009683 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:18406234 | DBBJ | BAC42568.1 | 561 | putative sterol dehydrogenase [Arabidopsis thaliana] |
| GI:18406234 | GenBank | AAK76515.1 | 561 | putative sterol dehydrogenase [Arabidopsis thaliana] |
| GI:18406234 | GenBank | ADT60925.1 | 561 | Sequence 2740 from patent US 7847156 |
| GI:18406234 | GenBank | AEC10266.1 | 561 | 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3 [Arabidopsis thaliana] |
| GI:18406234 | gnl | TIGR | 561 | putative sterol dehydrogenase [Arabidopsis thaliana] |
| GI:18406234 | SwissProt | A9X4U2.2 | 561 | RecName: Full=3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3; Short=At3BETAHSD/D3; AltName: Full=4alpha-carboxysterol-C3-dehydrogenase/C4-decarboxylase isoform 1-3; AltName: Full=Reticulon-like protein B20; Short=AtRTNLB20; AltName: Full=Sterol-4-alpha-carboxylate 3-dehydrogenase 3, decarboxylating [Arabidopsis thaliana] |
Related Sequences to LMP009683 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:18406234 | GenBank | ABD76542.1 | 561 | 4-alphacarboxysterol-dehydrogenase/C4-decarboxylase isoform 3 [Arabidopsis thaliana] |
| GI:18406234 | GenBank | EFH58162.1 | 562 | 3-beta hydroxysteroid dehydrogenase/isomerase family protein [Arabidopsis lyrata subsp. lyrata] |
| GI:18406234 | RefSeq | XP_002881903.1 | 562 | 3-beta hydroxysteroid dehydrogenase/isomerase family protein [Arabidopsis lyrata subsp. lyrata] |
| GI:18406234 | RefSeq | XP_010506213.1 | 563 | PREDICTED: 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3-like [Camelina sativa] |
| GI:18406234 | RefSeq | XP_010508434.1 | 563 | PREDICTED: 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3-like [Camelina sativa] |
| GI:18406234 | RefSeq | XP_010517903.1 | 563 | PREDICTED: 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3 [Camelina sativa] |