Gene/Proteome Database (LMPD)

LMPD ID
LMP009696
Gene ID
824381
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
3-ketoacyl-CoA synthase 15
Gene Symbol
KCS15
Synonyms
3-ketoacyl-CoA synthase 15; KCS15
Alternate Names
3-ketoacyl-CoA synthase 15
Chromosome
3
EC Number
2.3.1.199
Summary
Encodes KCS15, a member of the 3-ketoacyl-CoA synthase family involved in the biosynthesis of VLCFA (very long chain fatty acids).
Orthologs
View orthologs and multiple alignments for KCS15

Proteins

3-ketoacyl-CoA synthase 15
Refseq ID NP_190784
Protein GI 15231151
UniProt ID Q9SUY9
mRNA ID NM_115076
Length 451
RefSeq Status REVIEWED
MEKEATKMVNGGVKSKSPKGSPDFLGYNLRYVKLGYIYLLSLSRTFCFFLPPLLLLFIFVSRFLPILAFPLSTFFILLIYHYLTPSSVFLLDFSCYRPPDHLKITKSDFIELAMKSGNFNETAIELQRKVLDQSGIGEESYMPRVVFKPGHRVNLRDGREEAAMVIFGAIDELLAATKINVKHIKILVLNCGVLNTTPSLSAMVINHYKLRHNTESYNLGGMGCSAGVIAIDLAKDLLNAHQGSYALVVSTEIVSFTWYSGNDVALLPPNCFFRMGAAAVMLSSRRIDRWRAKYQLMQLVRTHKGMEDTSYKSIELREDRDGKQGLYVSRDVMEVGRHALKANIATLGRLEPSFEHICVLASSKKVLDDIHKDLKLTEENMEASRRTLERFGNTSSSSIWYELAYLEHKAKMKRGDRVWQIGFGSGFKCNSVVWKALKNIDPPRHNNPWNL

Gene Information

Entrez Gene ID
824381
Gene Name
3-ketoacyl-CoA synthase 15
Gene Symbol
KCS15
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016747 IEA:InterPro F transferase activity, transferring acyl groups other than amino-acyl groups
GO:0006633 IEA:UniProtKB-UniPathway P fatty acid biosynthetic process

Domain Information

InterPro Annotations

Accession Description
IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal
IPR013601 FAE1/Type III polyketide synthase-like protein
IPR016039 Thiolase-like
IPR016038 Thiolase-like, subgroup
IPR012392 Very-long-chain 3-ketoacyl-CoA synthase

UniProt Annotations

Entry Information

Gene Name
3-ketoacyl-CoA synthase 15
Protein Entry
KCS15_ARATH
UniProt ID
Q9SUY9
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity A very-long-chain acyl-CoA + malonyl-CoA = CoA + a very-long-chain 3-oxoacyl-CoA + CO(2).
Induction Repressed by herbicides such as flufenacet and benfuresate. {ECO:0000269|PubMed:12916765}.
Pathway Lipid metabolism; fatty acid biosynthesis.
Sequence Caution Sequence=AAM61287.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Similarity Belongs to the chalcone/stilbene synthases family. {ECO:0000305}.
Similarity Contains 1 FAE (fatty acid elongase) domain. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP009696 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15231151 RefSeq NP_190784 451 3-ketoacyl-CoA synthase 15

Identical Sequences to LMP009696 proteins

Reference Database Accession Length Protein Name
GI:15231151 EMBL CAW45900.1 451 unnamed protein product [Arabidopsis thaliana]
GI:15231151 EMBL CAW71160.1 451 unnamed protein product [Arabidopsis thaliana]
GI:15231151 EMBL CBC11402.1 451 unnamed protein product [Arabidopsis thaliana]
GI:15231151 EMBL CBD33821.1 451 unnamed protein product [Arabidopsis thaliana]
GI:15231151 EMBL CBC60826.1 451 unnamed protein product [Arabidopsis thaliana]
GI:15231151 GenBank AEE78906.1 451 3-ketoacyl-CoA synthase 15 [Arabidopsis thaliana]

Related Sequences to LMP009696 proteins

Reference Database Accession Length Protein Name
GI:15231151 GenBank AAM61287.1 444 beta-ketoacyl-CoA synthase like protein [Arabidopsis thaliana]
GI:15231151 GenBank ABK28598.1 452 unknown, partial [Arabidopsis thaliana]
GI:15231151 GenBank EFH54104.1 452 beta-ketoacyl-CoA synthase family protein [Arabidopsis lyrata subsp. lyrata]
GI:15231151 RefSeq XP_002877845.1 452 beta-ketoacyl-CoA synthase family protein [Arabidopsis lyrata subsp. lyrata]
GI:15231151 RefSeq XP_010503940.1 452 PREDICTED: 3-ketoacyl-CoA synthase 15-like isoform X1 [Camelina sativa]
GI:15231151 RefSeq XP_010426819.1 452 PREDICTED: 3-ketoacyl-CoA synthase 15 [Camelina sativa]