Gene/Proteome Database (LMPD)

LMPD ID
LMP009700
Gene ID
834398
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
3-ketoacyl-CoA synthase 20
Gene Symbol
KCS20
Synonyms
3-ketoacyl-CoA synthase 20; KCS20; MQD19.11; MQD19_11
Alternate Names
3-ketoacyl-CoA synthase 20
Chromosome
5
EC Number
2.3.1.199

Proteins

3-ketoacyl-CoA synthase 20
Refseq ID NP_199189
Protein GI 15239981
UniProt ID Q9FG87
mRNA ID NM_123743
Length 529
RefSeq Status REVIEWED
MSHNQNQPHRPVPVHVTNAEPNPNPNNLPNFLLSVRLKYVKLGYHYLISNALYILLLPLLAATIANLSSFTINDLSLLYNTLRFHFLSATLATALLISLSTAYFTTRPRRVFLLDFSCYKPDPSLICTRETFMDRSQRVGIFTEDNLAFQQKILERSGLGQKTYFPEALLRVPPNPCMEEARKEAETVMFGAIDAVLEKTGVKPKDIGILVVNCSLFNPTPSLSAMIVNKYKLRGNILSYNLGGMGCSAGLISIDLAKQMLQVQPNSYALVVSTENITLNWYLGNDRSMLLSNCIFRMGGAAVLLSNRSSDRSRSKYQLIHTVRTHKGADDNAFGCVYQREDNNAEETGKIGVSLSKNLMAIAGEALKTNITTLGPLVLPMSEQLLFFATLVARKVFKVKKIKPYIPDFKLAFEHFCIHAGGRAVLDEIEKNLDLSEWHMEPSRMTLNRFGNTSSSSLWYELAYSEAKGRIKRGDRTWQIAFGSGFKCNSAVWKALRTIDPMDEKTNPWIDEIDDFPVQVPRITPITSS

Gene Information

Entrez Gene ID
834398
Gene Name
3-ketoacyl-CoA synthase 20
Gene Symbol
KCS20
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0009922 IDA:TAIR F fatty acid elongase activity
GO:0006633 IEA:UniProtKB-UniPathway P fatty acid biosynthetic process
GO:0009409 IEP:TAIR P response to cold
GO:0009416 IEP:TAIR P response to light stimulus

KEGG Pathway Links

KEGG Pathway ID Description
ath01110 Biosynthesis of secondary metabolites
ath_M00415 Fatty acid biosynthesis, elongation, endoplasmic reticulum
ath00062 Fatty acid elongation

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-6803 phosphatidylcholine acyl editing

Domain Information

InterPro Annotations

Accession Description
IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal
IPR013601 FAE1/Type III polyketide synthase-like protein
IPR016039 Thiolase-like
IPR016038 Thiolase-like, subgroup
IPR012392 Very-long-chain 3-ketoacyl-CoA synthase

UniProt Annotations

Entry Information

Gene Name
3-ketoacyl-CoA synthase 20
Protein Entry
KCS19_ARATH
UniProt ID
Q9FG87
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity A very-long-chain acyl-CoA + malonyl-CoA = CoA + a very-long-chain 3-oxoacyl-CoA + CO(2).
Enzyme Regulation Inhibited by K3 herbicides such as alachlor, allidochlor, anilofos, cafenstrole, fentrazamide and flufenacet. {ECO:0000269|PubMed:15277688}.
Function Mediates the synthesis of VLCFAs from 22 to 26 carbons in length (e.g. C22, C24, C26). {ECO:0000269|PubMed:15277688}.
Induction Repressed by herbicides such as flufenacet and benfuresate. {ECO:0000269|PubMed:12916765}.
Pathway Lipid metabolism; fatty acid biosynthesis.
Similarity Belongs to the chalcone/stilbene synthases family. {ECO:0000305}.
Similarity Contains 1 FAE (fatty acid elongase) domain. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000269|PubMed:15277688}; Multi-pass membrane protein {ECO:0000269|PubMed:15277688}.
Tissue Specificity Expressed in aerial organs. {ECO:0000269|PubMed:15914083}.

Identical and Related Proteins

Unique RefSeq proteins for LMP009700 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15239981 RefSeq NP_199189 529 3-ketoacyl-CoA synthase 20

Identical Sequences to LMP009700 proteins

Reference Database Accession Length Protein Name
GI:15239981 DBBJ BAB11304.1 529 beta-ketoacyl-CoA synthase [Arabidopsis thaliana]
GI:15239981 GenBank AAL11613.1 529 AT5g43760/MQD19_11 [Arabidopsis thaliana]
GI:15239981 GenBank AAN12994.1 529 beta-ketoacyl-CoA synthase [Arabidopsis thaliana]
GI:15239981 gnl TAIR 529 3-ketoacyl-CoA synthase 20 [Arabidopsis thaliana]
GI:15239981 SwissProt Q9FG87.1 529 RecName: Full=3-ketoacyl-CoA synthase 19; Short=KCS-19; AltName: Full=Very long-chain fatty acid condensing enzyme 19; Short=VLCFA condensing enzyme 19 [Arabidopsis thaliana]

Related Sequences to LMP009700 proteins

Reference Database Accession Length Protein Name
GI:15239981 GenBank AAK59535.1 529 putative beta-ketoacyl-CoA synthase [Arabidopsis thaliana]
GI:15239981 GenBank EOA13197.1 529 hypothetical protein CARUB_v10026222mg [Capsella rubella]
GI:15239981 RefSeq XP_006280299.1 529 hypothetical protein CARUB_v10026222mg [Capsella rubella]
GI:15239981 RefSeq XP_010441988.1 564 PREDICTED: 3-ketoacyl-CoA synthase 19-like [Camelina sativa]
GI:15239981 RefSeq XP_010481829.1 529 PREDICTED: 3-ketoacyl-CoA synthase 19-like [Camelina sativa]
GI:15239981 RefSeq XP_010494354.1 529 PREDICTED: 3-ketoacyl-CoA synthase 19 [Camelina sativa]