Gene/Proteome Database (LMPD)

LMPD ID
LMP009709
Gene ID
816124
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
3-ketoacyl-CoA synthase 9
Gene Symbol
KCS9
Synonyms
3-ketoacyl-CoA synthase 9; F16F14.22; F16F14_22; KCS9
Alternate Names
3-ketoacyl-CoA synthase 9
Chromosome
2
EC Number
2.3.1.199
Summary
Encodes KCS9, a member of the 3-ketoacyl-CoA synthase family involved in the biosynthesis of VLCFA (very long chain fatty acids).
Orthologs
View orthologs and multiple alignments for KCS9

Proteins

3-ketoacyl-CoA synthase 9
Refseq ID NP_179223
Protein GI 15226724
UniProt ID Q9SIX1
mRNA ID NM_127184
Length 512
RefSeq Status REVIEWED
MEAANEPVNGGSVQIRTENNERRKLPNFLQSVNMKYVKLGYHYLITHLFKLCLVPLMAVLVTEISRLTTDDLYQIWLHLQYNLVAFIFLSALAIFGSTVYIMSRPRSVYLVDYSCYLPPESLQVKYQKFMDHSKLIEDFNESSLEFQRKILERSGLGEETYLPEALHCIPPRPTMMAAREESEQVMFGALDKLFENTKINPRDIGVLVVNCSLFNPTPSLSAMIVNKYKLRGNVKSFNLGGMGCSAGVISIDLAKDMLQVHRNTYAVVVSTENITQNWYFGNKKAMLIPNCLFRVGGSAILLSNKGKDRRRSKYKLVHTVRTHKGAVEKAFNCVYQEQDDNGKTGVSLSKDLMAIAGEALKANITTLGPLVLPISEQILFFMTLVTKKLFNSKLKPYIPDFKLAFDHFCIHAGGRAVIDELEKNLQLSQTHVEASRMTLHRFGNTSSSSIWYELAYIEAKGRMKKGNRVWQIAFGSGFKCNSAVWVALNNVKPSVSSPWEHCIDRYPVKLDF

Gene Information

Entrez Gene ID
816124
Gene Name
3-ketoacyl-CoA synthase 9
Gene Symbol
KCS9
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016747 IEA:InterPro F transferase activity, transferring acyl groups other than amino-acyl groups
GO:0006633 IEA:UniProtKB-UniPathway P fatty acid biosynthetic process
GO:0009409 IEP:TAIR P response to cold
GO:0009416 IEP:TAIR P response to light stimulus

KEGG Pathway Links

KEGG Pathway ID Description
ath01110 Biosynthesis of secondary metabolites
ath_M00415 Fatty acid biosynthesis, elongation, endoplasmic reticulum
ath00062 Fatty acid elongation

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-6803 phosphatidylcholine acyl editing

Domain Information

InterPro Annotations

Accession Description
IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal
IPR013601 FAE1/Type III polyketide synthase-like protein
IPR016039 Thiolase-like
IPR016038 Thiolase-like, subgroup
IPR012392 Very-long-chain 3-ketoacyl-CoA synthase

UniProt Annotations

Entry Information

Gene Name
3-ketoacyl-CoA synthase 9
Protein Entry
KCS9_ARATH
UniProt ID
Q9SIX1
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity A very-long-chain acyl-CoA + malonyl-CoA = CoA + a very-long-chain 3-oxoacyl-CoA + CO(2).
Induction Repressed by herbicides such as flufenacet and benfuresate. {ECO:0000269|PubMed:12916765}.
Pathway Lipid metabolism; fatty acid biosynthesis.
Sequence Caution Sequence=AK226284; Type=Frameshift; Positions=485; Evidence={ECO:0000305};
Similarity Belongs to the chalcone/stilbene synthases family. {ECO:0000305}.
Similarity Contains 1 FAE (fatty acid elongase) domain. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP009709 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15226724 RefSeq NP_179223 512 3-ketoacyl-CoA synthase 9

Identical Sequences to LMP009709 proteins

Reference Database Accession Length Protein Name
GI:15226724 GenBank ACW93740.1 512 Sequence 12704 from patent US 7569389
GI:15226724 GenBank ACX17074.1 512 Sequence 44423 from patent US 7569389
GI:15226724 GenBank AEC06480.1 512 3-ketoacyl-CoA synthase 9 [Arabidopsis thaliana]
GI:15226724 gnl TIGR 512 putative beta-ketoacyl-CoA synthase [Arabidopsis thaliana]
GI:15226724 SwissProt Q9SIX1.1 512 RecName: Full=3-ketoacyl-CoA synthase 9; Short=KCS-9; AltName: Full=Very long-chain fatty acid condensing enzyme 9; Short=VLCFA condensing enzyme 9 [Arabidopsis thaliana]

Related Sequences to LMP009709 proteins

Reference Database Accession Length Protein Name
GI:15226724 GenBank AAE84925.1 537 Sequence 10 from patent US 6307128
GI:15226724 GenBank ACW94285.1 512 Sequence 13441 from patent US 7569389
GI:15226724 GenBank ACX21472.1 512 Sequence 50368 from patent US 7569389
GI:15226724 GenBank EFH60419.1 511 hypothetical protein ARALYDRAFT_900287 [Arabidopsis lyrata subsp. lyrata]
GI:15226724 RefSeq XP_002884160.1 511 hypothetical protein ARALYDRAFT_900287 [Arabidopsis lyrata subsp. lyrata]
GI:15226724 RefSeq XP_006299088.1 511 hypothetical protein CARUB_v10015226mg [Capsella rubella]