Gene/Proteome Database (LMPD)
LMPD ID
LMP009710
Gene ID
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
3-ketoacyl-CoA thiolase 1
Gene Symbol
Synonyms
3-KETO-ACYL-COA THIOLASE 1; KAT1; peroxisomal 3-ketoacyl-CoA thiolase 4; PKT4; T1G11.4; T1G11_4
Alternate Names
3-ketoacyl-CoA thiolase 1
Chromosome
1
EC Number
2.3.1.16
Summary
EC2.3.1.16 thiolase.
Orthologs
Proteins
3-ketoacyl-CoA thiolase 1 | |
---|---|
Refseq ID | NP_171965 |
Protein GI | 15219797 |
UniProt ID | Q8LF48 |
mRNA ID | NM_100351 |
Length | 443 |
RefSeq Status | REVIEWED |
MEKATERQRILLRHLQPSSSSDASLSASACLSKDSAAYQYGDDVVIVAAQRTALCKAKRGSFKDTFPDELLASVLRALIEKTNVNPSEVGDIVVGTVLGPGSQRASECRMAAFYAGFPETVPIRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTTNPRGWKGSVNPNVKKFEQAHNCLLPMGITSENVAHRFNVSREEQDQAAVDSHRKAASATASGKFKDEITPVKTKIVDPKTGDEKPITVSVDDGIRPNTTLSGLAKLKPVFKEDGTTTAGNSSQLSDGAGAVLLMRRNVAMQKGLPILGVFRTFSAVGVDPAIMGVGPAVAIPAAVKAAGLELNDVDLFEINEAFASQFVYCRNKLGLDAEKINVNGGAIAIGHPLGATGARCVATLLHEMKRRGKDCRFGVVSMCIGSGMGAAAVFERGGGVDELCDVRKV |
Gene Information
Entrez Gene ID
Gene Name
3-ketoacyl-CoA thiolase 1
Gene Symbol
Species
Arabidopsis thaliana
Gene Ontology (GO Annotations)
GO ID | Source | Type | Description |
---|---|---|---|
GO:0005777 | IDA:TAIR | C | peroxisome |
GO:0005773 | IDA:TAIR | C | vacuole |
GO:0003988 | IEA:UniProtKB-EC | F | acetyl-CoA C-acyltransferase activity |
GO:0031408 | IEA:UniProtKB-KW | P | oxylipin biosynthetic process |
KEGG Pathway Links
KEGG Pathway ID | Description |
---|---|
ath01040 | Biosynthesis of unsaturated fatty acids |
ath_M00113 | Jasmonic acid biosynthesis |
ath04146 | Peroxisome |
ath_M00087 | beta-Oxidation |
Domain Information
InterPro Annotations
UniProt Annotations
Entry Information
Comments
Comment Type | Description |
---|---|
Catalytic Activity | Acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA. |
Function | Involved in fatty-acid beta-oxidation prior to gluconeogenesis during germination and subsequent seedling growth. Implicated in jasmonic acid (JA) biosynthesis (By similarity). {ECO:0000250}. |
Pathway | Lipid metabolism; fatty acid metabolism. |
Sequence Caution | Sequence=AAB80634.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; |
Similarity | Belongs to the thiolase family. {ECO:0000305}. |
Subcellular Location | Peroxisome {ECO:0000250}. |
Subunit | Homodimer. {ECO:0000250}. |
Tissue Specificity | Low levels in seedlings and leaves. {ECO:0000269|PubMed:11696182, ECO:0000269|PubMed:15141068}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP009710 (as displayed in Record Overview)
Protein GI | Database | Accession | Length | Protein Name |
---|---|---|---|---|
15219797 | RefSeq | NP_171965 | 443 | 3-ketoacyl-CoA thiolase 1 |
Identical Sequences to LMP009710 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:15219797 | GenBank | AAO00648.1 | 443 | Sequence 14 from patent US 6489461 |
GI:15219797 | GenBank | AAO30078.1 | 443 | putative acetyl-CoA acyltransferase [Arabidopsis thaliana] |
GI:15219797 | GenBank | ACW86547.1 | 443 | Sequence 2916 from patent US 7569389 |
GI:15219797 | GenBank | ACW87193.1 | 443 | Sequence 3794 from patent US 7569389 |
GI:15219797 | GenBank | AEE27736.1 | 443 | 3-ketoacyl-CoA thiolase 1 [Arabidopsis thaliana] |
GI:15219797 | SwissProt | Q8LF48.2 | 443 | RecName: Full=3-ketoacyl-CoA thiolase 1, peroxisomal; AltName: Full=Acetyl-CoA acyltransferase 1; AltName: Full=Beta-ketothiolase 1; AltName: Full=Peroxisomal 3-oxoacyl-CoA thiolase 1; Flags: Precursor [Arabidopsis thaliana] |
Related Sequences to LMP009710 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:15219797 | GenBank | AAB80634.1 | 460 | Strong similarity to Cucumis acetyl-CoA acyltransferase (gb|D70895) [Arabidopsis thaliana] |
GI:15219797 | GenBank | AAM61609.1 | 443 | putative acetyl-CoA acyltransferase [Arabidopsis thaliana] |
GI:15219797 | GenBank | ACW86546.1 | 453 | Sequence 2915 from patent US 7569389 |
GI:15219797 | GenBank | ACW87192.1 | 453 | Sequence 3793 from patent US 7569389 |
GI:15219797 | GenBank | EOA40415.1 | 444 | hypothetical protein CARUB_v10009140mg [Capsella rubella] |
GI:15219797 | RefSeq | XP_006307517.1 | 444 | hypothetical protein CARUB_v10009140mg [Capsella rubella] |