Gene/Proteome Database (LMPD)
LMPD ID
LMP009745
Gene ID
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
ABC transporter G family member 11
Gene Symbol
Synonyms
ABCG11; ARABIDOPSIS THALIANA WHITE-BROWN COMPLEX HOMOLOG PROTEIN 11; ATWBC11; COF1; CUTICULAR DEFECT AND ORGAN FUSION 1; DESPERADO; DSO; F2H15.7; F2H15_7; WBC11; white-brown complex homolog protein 11
Alternate Names
ABC transporter G family member 11
Chromosome
1
Summary
Encodes a plasma membrane-localized ATP-binding cassette transporter, that is required for cutin transport to the extracellular matrix.
Orthologs
Proteins
| ABC transporter G family member 11 | |
|---|---|
| Refseq ID | NP_173226 |
| Protein GI | 22329638 |
| UniProt ID | Q8RXN0 |
| mRNA ID | NM_101647 |
| Length | 703 |
| RefSeq Status | REVIEWED |
| MEIEASRQQTTVPVSVGGGNFPVGGLSPLSEAIWREKAPTEFVGDVSARLTWQDLTVMVTMGDGETQNVLEGLTGYAEPGSLTALMGPSGSGKSTMLDALASRLAANAFLSGTVLLNGRKTKLSFGTAAYVTQDDNLIGTLTVRETIWYSARVRLPDKMLRSEKRALVERTIIEMGLQDCADTVIGNWHLRGISGGEKRRVSIALEILMRPRLLFLDEPTSGLDSASAFFVTQTLRALSRDGRTVIASIHQPSSEVFELFDRLYLLSGGKTVYFGQASDAYEFFAQAGFPCPALRNPSDHFLRCINSDFDKVRATLKGSMKLRFEASDDPLEKITTAEAIRLLVDYYHTSDYYYTAKAKVEEISQFKGTILDSGGSQASFLLQTYTLTKRSFINMSRDFGYYWLRLLIYILVTVCIGTIYLNVGTSYSAILARGSCASFVFGFVTFMSIGGFPSFVEDMKVFQRERLNGHYGVAAFVIANTLSATPFLIMITFISGTICYFMVGLHPGFTHYLFFVLCLYASVTVVESLMMAIASIVPNFLMGIIIGAGIQGIFMLVSGFFRLPNDIPKPFWRYPMSYISFHFWALQGQYQNDLRGLTFDSQGSAFKIPGEYVLENVFQIDLHRSKWINLSVILSMIIIYRIIFFIMIKTNEDVTPWVRGYIARRRMKQKNGTQNTTVAPDGLTQSPSLRNYIATRTDGARRW | |
Gene Information
Entrez Gene ID
Gene Name
ABC transporter G family member 11
Gene Symbol
Species
Arabidopsis thaliana
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0009897 | IDA:TAIR | C | external side of plasma membrane |
| GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
| GO:0005886 | IDA:TAIR | C | plasma membrane |
| GO:0005524 | IEA:UniProtKB-KW | F | ATP binding |
| GO:0016887 | IEA:InterPro | F | ATPase activity |
| GO:0015245 | TAS:TAIR | F | fatty acid transporter activity |
| GO:0042803 | IPI:TAIR | F | protein homodimerization activity |
| GO:0010588 | IMP:TAIR | P | cotyledon vascular tissue pattern formation |
| GO:0080051 | IMP:TAIR | P | cutin transport |
| GO:0015908 | TAS:TAIR | P | fatty acid transport |
| GO:0009737 | IDA:UniProtKB | P | response to abscisic acid |
| GO:0009651 | IDA:UniProtKB | P | response to salt stress |
| GO:0009611 | IDA:UniProtKB | P | response to wounding |
| GO:0010222 | IGI:TAIR | P | stem vascular tissue pattern formation |
REACTOME Pathway Links
Domain Information
UniProt Annotations
Entry Information
Gene Name
ABC transporter G family member 11
Protein Entry
AB11G_ARATH
UniProt ID
Species
Arabidopsis
Comments
| Comment Type | Description |
|---|---|
| Developmental Stage | First observed in seed coat and the endosperm. During embryo development, expressed in the radical tip. In seedlings, localized in the cotyledons, root tip, and young leaves. As secondary root tips emerge, expressed in the pericycle during the initial cell divisions. In leaves, mostly detected in the expanding basal portion, trichomes and stomatal cells. In roots of mature plants, mainly expressed in lateral root primordia and developing lateral roots. In the inflorescence, found in all floral organs, predominantly in the anthers, styles, and young siliques. Upon anthesis and later, progressively restricted to the carpel. {ECO:0000269|PubMed:17727615, ECO:0000269|PubMed:17951461}. |
| Disruption Phenotype | Bushy phenotype. Abnormal cuticle and pollen grain shapes, reduced levels of wax and cutin monomers, unusual lipidic cytoplasmatic inclusions in epidermal cells, inter-organ postgenital fusions, and altered morphology of trichomes and pavement cells. Highly susceptibility to salt and reduced root branching. {ECO:0000269|PubMed:14675439, ECO:0000269|PubMed:17727615, ECO:0000269|PubMed:17951461, ECO:0000269|PubMed:17971336, ECO:0000269|PubMed:17989085}. |
| Function | Required for the cuticle and pollen coat development by controlling cutin and maybe wax transport to the extracellular matrix. Involved in developmental plasticity and stress responses. {ECO:0000269|PubMed:14675439, ECO:0000269|PubMed:17727615, ECO:0000269|PubMed:17951461, ECO:0000269|PubMed:17971336, ECO:0000269|PubMed:17989085}. |
| Induction | By light, NaCl, abscisic acid (ABA), wounding, and glucose stresses. Repressed by H(2)O(2) and cytokinin. {ECO:0000269|PubMed:14730060, ECO:0000269|PubMed:17951461, ECO:0000269|PubMed:17989085}. |
| Sequence Caution | Sequence=AAF97264.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; |
| Similarity | Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. {ECO:0000305}. |
| Similarity | Contains 1 ABC transmembrane type-2 domain. {ECO:0000305}. |
| Similarity | Contains 1 ABC transporter domain. {ECO:0000255|PROSITE-ProRule:PRU00434}. |
| Subcellular Location | Cell membrane {ECO:0000269|PubMed:17727615, ECO:0000269|PubMed:17951461, ECO:0000269|PubMed:17971336, ECO:0000269|PubMed:17989085}; Multi-pass membrane protein {ECO:0000269|PubMed:17727615, ECO:0000269|PubMed:17951461, ECO:0000269|PubMed:17971336, ECO:0000269|PubMed:17989085}. Note=Localized in a polar manner in the epidermis side facing the extracellular matrix (cuticle). |
| Subunit | Homodimer. {ECO:0000305}. |
| Tissue Specificity | Expressed in seedlings, roots, stems, leaves, flowers, and siliques, mostly in epidermis, trichomes, vasculatures and developing tissues. {ECO:0000269|PubMed:14730060, ECO:0000269|PubMed:17727615, ECO:0000269|PubMed:17951461, ECO:0000269|PubMed:17989085}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP009745 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 22329638 | RefSeq | NP_173226 | 703 | ABC transporter G family member 11 |
Identical Sequences to LMP009745 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:22329638 | GenBank | AAL87274.1 | 703 | putative ABC transporter protein [Arabidopsis thaliana] |
| GI:22329638 | GenBank | AAN12898.1 | 703 | putative ABC transporter protein [Arabidopsis thaliana] |
| GI:22329638 | GenBank | ACX15722.1 | 703 | Sequence 42593 from patent US 7569389 |
| GI:22329638 | GenBank | ACX16785.1 | 703 | Sequence 44033 from patent US 7569389 |
| GI:22329638 | GenBank | AEE29642.1 | 703 | ABC transporter G family member 11 [Arabidopsis thaliana] |
| GI:22329638 | SwissProt | Q8RXN0.1 | 703 | RecName: Full=ABC transporter G family member 11; Short=ABC transporter ABCG.11; Short=AtABCG11; AltName: Full=Protein CUTICULAR DEFECT AND ORGAN FUSION 1; AltName: Full=Protein DESPERADO; AltName: Full=Protein PERMEABLE LEAVES 1; AltName: Full=White-brown complex homolog protein 11; Short=AtWBC11 [Arabidopsis thaliana] |
Related Sequences to LMP009745 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:22329638 | GenBank | EFH66510.1 | 703 | abc transporter family protein [Arabidopsis lyrata subsp. lyrata] |
| GI:22329638 | GenBank | EOA39800.1 | 703 | hypothetical protein CARUB_v10008462mg [Capsella rubella] |
| GI:22329638 | GenBank | ESQ35015.1 | 703 | hypothetical protein EUTSA_v10006960mg [Eutrema salsugineum] |
| GI:22329638 | RefSeq | XP_002890251.1 | 703 | abc transporter family protein [Arabidopsis lyrata subsp. lyrata] |
| GI:22329638 | RefSeq | XP_006306902.1 | 703 | hypothetical protein CARUB_v10008462mg [Capsella rubella] |
| GI:22329638 | RefSeq | XP_006416662.1 | 703 | hypothetical protein EUTSA_v10006960mg [Eutrema salsugineum] |