Gene/Proteome Database (LMPD)

LMPD ID
LMP009775
Gene ID
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
acyl-CoA binding protein 1
Gene Symbol
Synonyms
ACBP; ACBP1; ACYL-COA BINDING PROTEIN; acyl-CoA binding protein 1; MYN8.8; MYN8_8
Alternate Names
acyl-CoA binding protein 1
Chromosome
5

Proteins

acyl-CoA binding protein 1
Refseq ID NP_200159
Protein GI 15238757
UniProt ID Q9SM23
mRNA ID NM_124726
Length 338
RefSeq Status REVIEWED
MADWYQLAQSIIFGLIFAYLLAKLISILLAFKDENLSLTRNHTTQSEYENLRKVETLTGISGETDSLIAEQGSLRGDEDESDDDDWEGVESTELDEAFSAATAFVAAAASDRLSQKVSNELQLQLYGLYKIATEGPCTAPQPSALKMTARAKWQAWQKLGAMPPEEAMEKYIDLVTQLYPAWVEGGSKRRNRSGEAAGPMGPVFSSLVYEEESDNELKIDAIHAFAREGEVENLLKCIENGIPVNARDSEGRTPLHWAIDRGHLNVAEALVDKNADVNAKDNEGQTSLHYAVVCEREALAEFLVKQKADTTIKDEDGNSPLDLCESEWSWMREKKDSN

Gene Information

Entrez Gene ID
Gene Name
acyl-CoA binding protein 1
Gene Symbol
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IEA:UniProtKB-KW C endoplasmic reticulum
GO:0005576 IEA:UniProtKB-KW C extracellular region
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0009505 IDA:TAIR C plant-type cell wall
GO:0005886 IDA:TAIR C plasma membrane
GO:0000062 IDA:TAIR F fatty-acyl-CoA binding
GO:0032791 IDA:TAIR F lead ion binding
GO:0008289 IDA:TAIR F lipid binding
GO:0070300 IDA:TAIR F phosphatidic acid binding
GO:0006629 IMP:TAIR P lipid metabolic process
GO:0006869 TAS:TAIR P lipid transport
GO:0010029 IMP:TAIR P regulation of seed germination
GO:1900140 IMP:TAIR P regulation of seedling development
GO:0009737 IEP:TAIR P response to abscisic acid
GO:0009409 IMP:TAIR P response to cold
GO:0010288 IEP:UniProtKB P response to lead ion
GO:0010162 IMP:TAIR P seed dormancy process

Domain Information

InterPro Annotations

Accession Description
IPR000582 Acyl-CoA-binding protein, ACBP
IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain
IPR014352 FERM/acyl-CoA-binding protein, 3-helical bundle

UniProt Annotations

Entry Information

Gene Name
acyl-CoA binding protein 1
Protein Entry
ACBP1_ARATH
UniProt ID
Species
Arabidopsis

Comments

Comment Type Description
Developmental Stage Expressed in embryos at the cotyledons, hypocotyls, procambiums, especially in epidermal cells and axis. {ECO:0000269|PubMed:10363372}.
Disruption Phenotype Increased sensitivity to lead ions. {ECO:0000269|PubMed:18182029}.
Function Binds medium- and long-chain acyl-CoA esters with very high affinity. Can interact in vitro with arachidonyl-CoA, barely with oleoyl-CoA, but not with palmitoyl-CoA. Confers tolerance and binds to lead ions Pb(2+), probably by promoting lead translocation from roots to shoots. May function as an intracellular carrier of acyl-CoA esters (By similarity). {ECO:0000250}.
Induction In roots by lead. {ECO:0000269|PubMed:18182029}.
Ptm Glycosylated. In seeds, localized in the outer integument. {ECO:0000269|PubMed:9862500}.
Similarity Belongs to the ACBP family. {ECO:0000305}.
Similarity Contains 1 ACB (acyl-CoA-binding) domain. {ECO:0000255|PROSITE-ProRule:PRU00573}.
Similarity Contains 3 ANK repeats. {ECO:0000255|PROSITE- ProRule:PRU00023}.
Subcellular Location Cell membrane; Single-pass membrane protein. Secreted, cell wall. Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Detected in the cell walls of the outer integument cells at the seed coat.
Subunit Interacts with RAP2-12. {ECO:0000269|PubMed:22020282}.
Tissue Specificity Expressed at low levels in roots, stems, leaves, flowers, and siliques, especially within seeds. {ECO:0000269|PubMed:9862500, ECO:0000269|Ref.9}.

Identical and Related Proteins

Unique RefSeq proteins for LMP009775 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15238757 RefSeq NP_200159 338 acyl-CoA binding protein 1

Identical Sequences to LMP009775 proteins

Reference Database Accession Length Protein Name
GI:15238757 DBBJ BAA97324.1 338 unnamed protein product [Arabidopsis thaliana]
GI:15238757 GenBank AAL24363.1 338 Unknown protein [Arabidopsis thaliana]
GI:15238757 GenBank AAM13382.1 338 unknown protein [Arabidopsis thaliana]
GI:15238757 GenBank AAF08323.2 338 acyl-CoA binding protein [Arabidopsis thaliana]
GI:15238757 gnl TAIR 338 acyl-CoA binding protein 1 [Arabidopsis thaliana]
GI:15238757 SwissProt Q9SM23.2 338 RecName: Full=Acyl-CoA-binding domain-containing protein 1; Short=Acyl-CoA binding protein 1 [Arabidopsis thaliana]

Related Sequences to LMP009775 proteins

Reference Database Accession Length Protein Name
GI:15238757 GenBank AAD03482.2 338 acyl-CoA binding protein [Arabidopsis thaliana]
GI:15238757 GenBank AAM65019.1 338 putative acyl-CoA binding protein [Arabidopsis thaliana]
GI:15238757 GenBank AED37544.1 338 Sequence 27 from patent US 7880053
GI:15238757 GenBank EOA13650.1 343 hypothetical protein CARUB_v10026721mg [Capsella rubella]
GI:15238757 RefSeq XP_006280752.1 343 hypothetical protein CARUB_v10026721mg [Capsella rubella]
GI:15238757 RefSeq XP_010482744.1 341 PREDICTED: acyl-CoA-binding domain-containing protein 1 [Camelina sativa]