Gene/Proteome Database (LMPD)

LMPD ID
LMP009776
Gene ID
828891
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
acyl-CoA binding protein 2
Gene Symbol
ACBP2
Synonyms
acyl-CoA binding protein 2; ACYL-COA BINDING PROTEIN ACBP2; T27E11.20; T27E11_20
Alternate Names
acyl-CoA binding protein 2
Chromosome
4
Summary
Encodes acyl-CoA-binding protein with ankyrin repeats
Orthologs
View orthologs and multiple alignments for ACBP2

Proteins

acyl-CoA binding protein 2
Refseq ID NP_194507
Protein GI 15234270
UniProt ID Q9STP8
mRNA ID NM_118916
Length 354
RefSeq Status REVIEWED
MGDWAQLAQSVILGLIFSYLLAKLISIVVTFKEDNLSLTRHPEESQLEIKPEGVDSRRLDSSCGGFGGEADSLVAEQGSSRSDSVAGDDSEEDDDWEGVESTELDEAFSAATLFVTTAAADRLSQKVPSDVQQQLYGLYKIATEGPCTAPQPSALKMTARAKWQAWQKLGAMPPEEAMEKYIEIVTQLYPTWLDGGVKAGSRGGDDAASNSRGTMGPVFSSLVYDEESENELKIDAIHGFAREGEVENLLKSIESGIPVNARDSEGRTPLHWAIDRGHLNIAKVLVDKNADVNAKDNEGQTPLHYAVVCDREAIAEFLVKQNANTAAKDEDGNSPLDLCESDWPWIRDSAKQAD

Gene Information

Entrez Gene ID
828891
Gene Name
acyl-CoA binding protein 2
Gene Symbol
ACBP2
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IDA:TAIR C endoplasmic reticulum
GO:0009514 IDA:UniProtKB C glyoxysome
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005886 IDA:UniProtKB C plasma membrane
GO:0000062 IDA:UniProtKB F fatty-acyl-CoA binding
GO:0032791 IDA:TAIR F lead ion binding
GO:0008289 IEA:UniProtKB-KW F lipid binding
GO:0006869 TAS:TAIR P lipid transport
GO:0010288 IEP:UniProtKB P response to lead ion

Domain Information

InterPro Annotations

Accession Description
IPR000582 Acyl-CoA-binding protein, ACBP
IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain
IPR014352 FERM/acyl-CoA-binding protein, 3-helical bundle

UniProt Annotations

Entry Information

Gene Name
acyl-CoA binding protein 2
Protein Entry
ACBP2_ARATH
UniProt ID
Q9STP8
Species
Arabidopsis

Comments

Comment Type Description
Function Binds medium- and long-chain acyl-CoA esters with very high affinity. Can interact in vitro with palmitoyl-CoA, but not with oleoyl-CoA. Binds to lead ions (Pb). May function as an intracellular carrier of acyl-CoA esters. Required for proper phospholipid and, to a lower extent, galactolipid composition. {ECO:0000269|PubMed:11202434, ECO:0000269|PubMed:15604682, ECO:0000269|PubMed:18182029, ECO:0000269|Ref.2}.
Induction In roots by lead. {ECO:0000269|PubMed:18182029}.
Interaction Q9SZN7:HIPP26; NbExp=5; IntAct=EBI-368234, EBI-2008207; P42736:RAP2-3; NbExp=3; IntAct=EBI-368234, EBI-368243;
Similarity Belongs to the ACBP family. {ECO:0000305}.
Similarity Contains 1 ACB (acyl-CoA-binding) domain. {ECO:0000255|PROSITE-ProRule:PRU00573}.
Similarity Contains 2 ANK repeats. {ECO:0000255|PROSITE- ProRule:PRU00023}.
Subcellular Location Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein.
Subunit Interacts (via ankyrin repeats) with HIPP26 and the ethylene-responsive element-binding proteins RAP2-3/EBP and RAP2- 12. Interacts with CSE. {ECO:0000269|PubMed:15159625, ECO:0000269|PubMed:18823312, ECO:0000269|PubMed:20345607, ECO:0000269|PubMed:22020282}.
Tissue Specificity Mostly expressed in roots and flowers, and, to a lower extent, in stems, pods and leaves (at protein level). {ECO:0000269|PubMed:11202434, ECO:0000269|Ref.2}.

Identical and Related Proteins

Unique RefSeq proteins for LMP009776 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15234270 RefSeq NP_194507 354 acyl-CoA binding protein 2

Identical Sequences to LMP009776 proteins

Reference Database Accession Length Protein Name
GI:15234270 GenBank AAL90917.1 354 AT4g27780/T27E11_20 [Arabidopsis thaliana]
GI:15234270 GenBank AAM66045.1 354 putative acyl-CoA binding protein [Arabidopsis thaliana]
GI:15234270 GenBank AAM67425.1 354 AT4g27780/T27E11_20 [Arabidopsis thaliana]
GI:15234270 GenBank AED37545.1 354 Sequence 28 from patent US 7880053
GI:15234270 GenBank AEE85391.1 354 acyl-CoA binding protein 2 [Arabidopsis thaliana]
GI:15234270 SwissProt Q9STP8.1 354 RecName: Full=Acyl-CoA-binding domain-containing protein 2; Short=Acyl-CoA binding protein 2 [Arabidopsis thaliana]

Related Sequences to LMP009776 proteins

Reference Database Accession Length Protein Name
GI:15234270 GenBank EOA16914.1 353 hypothetical protein CARUB_v10005137mg [Capsella rubella]
GI:15234270 GenBank ESQ54482.1 354 hypothetical protein EUTSA_v10025574mg [Eutrema salsugineum]
GI:15234270 RefSeq XP_006284016.1 353 hypothetical protein CARUB_v10005137mg [Capsella rubella]
GI:15234270 RefSeq XP_006413029.1 354 hypothetical protein EUTSA_v10025574mg [Eutrema salsugineum]
GI:15234270 RefSeq XP_010433314.1 359 PREDICTED: acyl-CoA-binding domain-containing protein 2-like [Camelina sativa]
GI:15234270 RefSeq XP_010448079.1 356 PREDICTED: acyl-CoA-binding domain-containing protein 2 [Camelina sativa]