Gene/Proteome Database (LMPD)

LMPD ID
LMP009810
Gene ID
818354
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
aldo-keto reductase family 4 member C9
Gene Symbol
AT2G37770
Synonyms
T8P21.32
Alternate Names
aldo-keto reductase family 4 member C9
Chromosome
2
EC Number
1.1.1.-

Proteins

aldo-keto reductase family 4 member C9
Refseq ID NP_001031505
Protein GI 79324628
UniProt ID Q0PGJ6
mRNA ID NM_001036428
Length 315
RefSeq Status REVIEWED
MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTGSFLVHETLSPYKSIEELWDGEI
aldo-keto reductase family 4 member C9
Refseq ID NP_181313
Protein GI 42569711
UniProt ID Q0PGJ6
mRNA ID NM_129333
Length 283
RefSeq Status REVIEWED
MANAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSVSITRLTNPFTFYFIHSLNDFFFPGILAIRFSRDNMAEERCFEEPDTEYGCGKTRKESCASRPSLGTPNGSQCASQEYK

Gene Information

Entrez Gene ID
818354
Gene Name
aldo-keto reductase family 4 member C9
Gene Symbol
AT2G37770
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009507 IDA:TAIR C chloroplast
GO:0008106 IDA:TAIR F alcohol dehydrogenase (NADP+) activity
GO:0004033 IDA:UniProtKB F aldo-keto reductase (NADP) activity
GO:0070401 IDA:UniProtKB F NADP+ binding
GO:0016229 IDA:UniProtKB F steroid dehydrogenase activity
GO:0055114 IDA:TAIR P oxidation-reduction process
GO:0009409 IEP:UniProtKB P response to cold
GO:0009651 IEP:UniProtKB P response to salt stress
GO:0009636 IEA:UniProtKB-KW P response to toxic substance
GO:0009414 IEP:UniProtKB P response to water deprivation

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-6786 detoxification of reactive carbonyls in chloroplasts
PWY-6786 detoxification of reactive carbonyls in chloroplasts
PWY-5453 methylglyoxal degradation III
PWY-5410 traumatin and (Z)-3-hexen-1-yl acetate biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR001395 Aldo/keto reductase
IPR018170 Aldo/keto reductase, conserved site
IPR020471 Aldo/keto reductase subgroup
IPR023210 NADP-dependent oxidoreductase domain

UniProt Annotations

Entry Information

Gene Name
aldo-keto reductase family 4 member C9
Protein Entry
AKRC9_ARATH
UniProt ID
Q0PGJ6
Species
Arabidopsis

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q0PGJ6-1; Sequence=Displayed; Name=2; IsoId=Q0PGJ6-2; Sequence=VSP_040016, VSP_040017; Note=No experimental confirmation available.;
Biophysicochemical Properties Kinetic parameters: KM=1445 uM for benzaldehyde {ECO:0000269|PubMed:19616008}; KM=102 uM for 3-fluorobenzaldehyde {ECO:0000269|PubMed:19616008}; KM=270 uM for cinnamylaldehyde {ECO:0000269|PubMed:19616008}; KM=261 uM for 3-hydroxybenzaldehyde {ECO:0000269|PubMed:19616008}; KM=82 uM for isopropylbenzaldehyde {ECO:0000269|PubMed:19616008}; KM=4.4 uM for 9,10-phenanthrenequinone {ECO:0000269|PubMed:19616008}; KM=5.49 mM for 2-E-hexenal {ECO:0000269|PubMed:19616008}; KM=4 mM for 4-hydroxy-2-nonenal {ECO:0000269|PubMed:19616008}; KM=51 mM for malondialdehyde {ECO:0000269|PubMed:19616008}; KM=0.46 mM for methylglyoxal {ECO:0000269|PubMed:19616008}; KM=2.2 mM for glyceraldehyde {ECO:0000269|PubMed:19616008}; KM=10.2 mM for glyoxal {ECO:0000269|PubMed:19616008}; KM=2.8 mM for erythrose {ECO:0000269|PubMed:19616008}; KM=238 mM for xylose {ECO:0000269|PubMed:19616008}; KM=240 mM for arabinose {ECO:0000269|PubMed:19616008}; KM=760 mM for glucose {ECO:0000269|PubMed:19616008}; KM=121 mM for galactose {ECO:0000269|PubMed:19616008};
Function Oxidoreductase acting on a broad range of substrates: reduces ketosteroids, aromatic aldehydes, ketones, sugars and other aliphatic aldehydes, and oxidizes hydroxysteroids. May function as detoxifiying enzyme by reducing a range of toxic aldehydes and ketones produced during stress. {ECO:0000269|PubMed:19616008}.
Induction By drought, salt and cold stresses. {ECO:0000269|PubMed:19616008}.
Sequence Caution Sequence=AAC23647.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BX820913; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
Similarity Belongs to the aldo/keto reductase family. {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP009810 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
79324628 RefSeq NP_001031505 315 aldo-keto reductase family 4 member C9
42569711 RefSeq NP_181313 283 aldo-keto reductase family 4 member C9

Identical Sequences to LMP009810 proteins

Reference Database Accession Length Protein Name
GI:79324628 GenBank ABH07515.1 315 aldo-keto reductase [Arabidopsis thaliana]
GI:79324628 GenBank ADT60644.1 315 Sequence 2178 from patent US 7847156
GI:42569711 GenBank AEC09448.1 283 aldo-keto reductase family 4 member C9 [Arabidopsis thaliana]
GI:79324628 GenBank AEC09449.1 315 aldo-keto reductase family 4 member C9 [Arabidopsis thaliana]
GI:79324628 RefSeq XP_004253292.1 315 PREDICTED: aldo-keto reductase family 4 member C9 [Solanum lycopersicum]
GI:79324628 SwissProt Q0PGJ6.1 315 RecName: Full=Aldo-keto reductase family 4 member C9 [Arabidopsis thaliana]

Related Sequences to LMP009810 proteins

Reference Database Accession Length Protein Name
GI:79324628 EMBL CDY64988.1 315 BnaA05g34870D [Brassica napus]
GI:79324628 GenBank AAO42123.1 304 putative aldo/keto reductase, partial [Arabidopsis thaliana]
GI:42569711 GenBank ABH07515.1 315 aldo-keto reductase [Arabidopsis thaliana]
GI:79324628 GenBank EFH55967.1 315 oxidoreductase [Arabidopsis lyrata subsp. lyrata]
GI:42569711 GenBank ADT60644.1 315 Sequence 2178 from patent US 7847156
GI:42569711 GenBank AEC09449.1 315 aldo-keto reductase family 4 member C9 [Arabidopsis thaliana]
GI:79324628 GenBank KFK36670.1 315 hypothetical protein AALP_AA4G154600 [Arabis alpina]
GI:42569711 gnl TIGR 290 putative alcohol dehydrogenase [Arabidopsis thaliana]
GI:42569711 RefSeq NP_001031505.1 315 aldo-keto reductase family 4 member C9 [Arabidopsis thaliana]
GI:79324628 RefSeq XP_002879708.1 315 oxidoreductase [Arabidopsis lyrata subsp. lyrata]
GI:79324628 RefSeq XP_006410968.1 315 hypothetical protein EUTSA_v10016962mg [Eutrema salsugineum]
GI:42569711 SwissProt Q0PGJ6.1 315 RecName: Full=Aldo-keto reductase family 4 member C9 [Arabidopsis thaliana]