Gene/Proteome Database (LMPD)

LMPD ID
LMP009843
Gene ID
843703
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
alpha dioxygenase
Gene Symbol
ALPHA DOX2
Synonyms
alpha dioxygenase; ALPHA DOX2; F25P22.10; F25P22_10
Alternate Names
alpha dioxygenase
Chromosome
1
EC Number
1.14.99.-
Summary
Encodes an alpha dioxygenase. Recombinant protein catalyzes the conversion of a wide range of fatty acids into 2(R)-hydroperoxy derivatives.
Orthologs
View orthologs and multiple alignments for ALPHA DOX2

Proteins

alpha dioxygenase
Refseq ID NP_001185393
Protein GI 334183898
UniProt ID Q9C9U3
mRNA ID NM_001198464
Length 640
RefSeq Status REVIEWED
MGFSPSSSWFLHPQLHHVVSKMSYFDAFLFYIVHLVDKLGLWHRFPVLLGVAYLGLRRHLHQRYNLVHVGPINGQGYDTDEFCYRTADGKCNHPSDNTIGSQGSFIGRNMPPSTSQYGFFCQYFFFPENLEKKIVVATKLLARKRFIDNGDQFNVIACSWIQFMIHDWVDHLEDTHQIELEAPEEVASGCPLKSFKFLRTKKVPTDDHHKSGAVNTRTPWWDGSVIYGNDETGMRRVRVFKDGKLKISGDGLLERDERGVPISGDIRNSWSGFSLLQALFVKEHNSVCDMLKERYPDFDDEKLYRTARLVTAAVIAKVHTIDWTIELLKTDTLTAGMRINWYGFFGKKVKDMVGARFGPLFSGLVGLKKPNDHGVPYSLTEEFVSVYRMHCLLPETLILRDMNSENVDKENPAIEREIPMTELIGKKAGEKASKLGFEQLLVSMGHQSCGALTLWNYPNWMRNLVAQDIDGEDRPHLIDMAALEIYRDRERGVPRYNEFRKNLLMSPISKWEELTDDEEAIKVLREVYEDDIEKLDLNVGLHAEKKIKGFAISETAFFIFLLVASRRLEADRFFTTNFNEKTYTKEGLEWVNTTETLKDVIDRHFPRLTDQWMRCSSAFSVWGSDPNPKNWVPLYLRSAP
alpha dioxygenase
Refseq ID NP_177509
Protein GI 15219521
UniProt ID Q9C9U3
mRNA ID NM_106027
Length 631
RefSeq Status REVIEWED
MGFSPSSSWFLHPQLHHVVSKMSYFDAFLFYIVHLVDKLGLWHRFPVLLGVAYLGLRRHLHQRYNLVHVGPINGQGYDTDEFCYRTADGKCNHPSDNTIGSQGSFIGRNMPPSTSQYGILDPHPSVVATKLLARKRFIDNGDQFNVIACSWIQFMIHDWVDHLEDTHQIELEAPEEVASGCPLKSFKFLRTKKVPTDDHHKSGAVNTRTPWWDGSVIYGNDETGMRRVRVFKDGKLKISGDGLLERDERGVPISGDIRNSWSGFSLLQALFVKEHNSVCDMLKERYPDFDDEKLYRTARLVTAAVIAKVHTIDWTIELLKTDTLTAGMRINWYGFFGKKVKDMVGARFGPLFSGLVGLKKPNDHGVPYSLTEEFVSVYRMHCLLPETLILRDMNSENVDKENPAIEREIPMTELIGKKAGEKASKLGFEQLLVSMGHQSCGALTLWNYPNWMRNLVAQDIDGEDRPHLIDMAALEIYRDRERGVPRYNEFRKNLLMSPISKWEELTDDEEAIKVLREVYEDDIEKLDLNVGLHAEKKIKGFAISETAFFIFLLVASRRLEADRFFTTNFNEKTYTKEGLEWVNTTETLKDVIDRHFPRLTDQWMRCSSAFSVWGSDPNPKNWVPLYLRSAP

Gene Information

Entrez Gene ID
843703
Gene Name
alpha dioxygenase
Gene Symbol
ALPHA DOX2
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0051213 IEA:UniProtKB-KW F dioxygenase activity
GO:0020037 IEA:InterPro F heme binding
GO:0046872 IEA:UniProtKB-KW F metal ion binding
GO:0004601 IEA:UniProtKB-KW F peroxidase activity
GO:0031408 IEA:UniProtKB-KW P oxylipin biosynthetic process
GO:0006979 IEA:InterPro P response to oxidative stress

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-2501 fatty acid alpha-oxidation I

Domain Information

InterPro Annotations

Accession Description
IPR019791 Haem peroxidase, animal
IPR010255 Haem_peroxidase

UniProt Annotations

Entry Information

Gene Name
alpha dioxygenase
Protein Entry
DOX2_ARATH
UniProt ID
Q9C9U3
Species
Arabidopsis

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9C9U3-1; Sequence=Displayed; Name=2; IsoId=Q9C9U3-2; Sequence=VSP_044438; Note=Derived from EST data. No experimental confirmation available.;
Developmental Stage Accumulates progressively during senescence induced by detachment of leaves. In flowers, expressed in anthers and ovules prior to fertilization, and in siliques, present in developing seeds. {ECO:0000269|PubMed:19759339}.
Function Alpha-dioxygenase that catalyzes the primary oxygenation of fatty acids into oxylipins. May be involved in the senescence process. {ECO:0000269|PubMed:19759339}.
Similarity Belongs to the peroxidase family. {ECO:0000255|PROSITE-ProRule:PRU00298}.
Tissue Specificity Expressed in seedlings (cotyledons, young leaves, and hypocotyls), flowers, siliques and old leaves. {ECO:0000269|PubMed:17369372, ECO:0000269|PubMed:19759339}.

Identical and Related Proteins

Unique RefSeq proteins for LMP009843 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
334183898 RefSeq NP_001185393 640 alpha dioxygenase
15219521 RefSeq NP_177509 631 alpha dioxygenase

Identical Sequences to LMP009843 proteins

Reference Database Accession Length Protein Name
GI:15219521 GenBank AAG52078.1 631 feebly-like protein; 35361-32165 [Arabidopsis thaliana]
GI:15219521 GenBank AAL91172.1 631 feebly-like protein [Arabidopsis thaliana]
GI:15219521 GenBank AAM91143.1 631 feebly-like protein [Arabidopsis thaliana]
GI:15219521 GenBank AEE35496.1 631 alpha dioxygenase [Arabidopsis thaliana]
GI:334183898 GenBank AEE35497.1 640 alpha dioxygenase [Arabidopsis thaliana]
GI:15219521 GenBank AGA39955.1 631 Sequence 15 from patent US 8318688
GI:15219521 SwissProt Q9C9U3.1 631 RecName: Full=Alpha-dioxygenase 2; Short=Alpha DOX2; AltName: Full=Fatty acid dioxygenase AlphaDOX2; Flags: Precursor [Arabidopsis thaliana]

Related Sequences to LMP009843 proteins

Reference Database Accession Length Protein Name
GI:334183898 GenBank AAG52078.1 631 feebly-like protein; 35361-32165 [Arabidopsis thaliana]
GI:334183898 GenBank AAM91143.1 631 feebly-like protein [Arabidopsis thaliana]
GI:15219521 GenBank EFH65199.1 631 hypothetical protein ARALYDRAFT_895230 [Arabidopsis lyrata subsp. lyrata]
GI:334183898 GenBank AEE35496.1 631 alpha dioxygenase [Arabidopsis thaliana]
GI:15219521 GenBank AEE35497.1 640 alpha dioxygenase [Arabidopsis thaliana]
GI:334183898 GenBank AGA39955.1 631 Sequence 15 from patent US 8318688
GI:334183898 RefSeq NP_177509.1 631 alpha dioxygenase [Arabidopsis thaliana]
GI:15219521 RefSeq XP_002888940.1 631 hypothetical protein ARALYDRAFT_895230 [Arabidopsis lyrata subsp. lyrata]
GI:15219521 RefSeq NP_001185393.1 640 alpha dioxygenase [Arabidopsis thaliana]
GI:15219521 RefSeq XP_010428303.1 631 PREDICTED: alpha-dioxygenase 2 [Camelina sativa]
GI:15219521 RefSeq XP_010471435.1 631 PREDICTED: alpha-dioxygenase 2-like [Camelina sativa]
GI:334183898 SwissProt Q9C9U3.1 631 RecName: Full=Alpha-dioxygenase 2; Short=Alpha DOX2; AltName: Full=Fatty acid dioxygenase AlphaDOX2; Flags: Precursor [Arabidopsis thaliana]