Gene/Proteome Database (LMPD)

LMPD ID
LMP009899
Gene ID
834758
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
BAX inhibitor 1
Gene Symbol
BI1
Synonyms
ARABIDOPSIS BAX INHIBITOR 1; ATBI-1; ATBI1; BAX inhibitor 1; BAX INHIBITOR 1; BI-1; BI1; K14A3.7; K14A3_7
Alternate Names
BAX inhibitor 1
Chromosome
5

Proteins

BAX inhibitor 1
Refseq ID NP_199523
Protein GI 15238017
UniProt ID Q9LD45
mRNA ID NM_124083
Length 247
RefSeq Status REVIEWED
MDAFSSFFDSQPGSRSWSYDSLKNFRQISPAVQNHLKRVYLTLCCALVASAFGAYLHVLWNIGGILTTIGCIGTMIWLLSCPPYEHQKRLSLLFVSAVLEGASVGPLIKVAIDVDPSILITAFVGTAIAFVCFSAAAMLARRREYLYLGGLLSSGLSMLMWLQFASSIFGGSASIFKFELYFGLLIFVGYMVVDTQEIIEKAHLGDMDYVKHSLTLFTDFVAVFVRILIIMLKNSADKEEKKKKRRN

Gene Information

Entrez Gene ID
834758
Gene Name
BAX inhibitor 1
Gene Symbol
BI1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IDA:TAIR C cytoplasm
GO:0005783 IDA:TAIR C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005635 IDA:TAIR C nuclear envelope
GO:0006915 IEA:UniProtKB-KW P apoptotic process
GO:0006983 IMP:TAIR P ER overload response
GO:0043066 IEA:InterPro P negative regulation of apoptotic process
GO:0043069 IMP:TAIR P negative regulation of programmed cell death
GO:0009414 IEP:TAIR P response to water deprivation
GO:0000038 IMP:TAIR P very long-chain fatty acid metabolic process

Domain Information

InterPro Annotations

Accession Description
IPR006213 Bax inhibitor 1, conserved site
IPR006214 Bax inhibitor 1-related

UniProt Annotations

Entry Information

Gene Name
BAX inhibitor 1
Protein Entry
BI1_ARATH
UniProt ID
Q9LD45
Species
Arabidopsis

Comments

Comment Type Description
Disruption Phenotype No visible phenotype under normal growth conditions. Accelerated methyl jasmonate-induced leaf senescence. Enhanced sensitivity to water stress, heat shock, toxin, tunicamycin and pathogens. {ECO:0000269|PubMed:16507080, ECO:0000269|PubMed:18039663, ECO:0000269|PubMed:19674971, ECO:0000269|PubMed:20298483, ECO:0000269|PubMed:22563118}.
Function Suppressor of apoptosis. Modulator of endoplasmic reticulum stress-mediated programmed cell death. Involved in methyl jasmonate-induced leaf senescence through regulating cytoplasmic calcium level. {ECO:0000269|PubMed:16507080, ECO:0000269|PubMed:18039663, ECO:0000269|PubMed:22563118}.
Induction Up-regulated by water stress, heat-shock, mycotoxin and pathogens. {ECO:0000269|PubMed:16507080, ECO:0000269|PubMed:19674971, ECO:0000269|PubMed:20298483}.
Interaction P59220:CAM7; NbExp=2; IntAct=EBI-1644586, EBI-1236031; O48845:CYTB5-B; NbExp=5; IntAct=EBI-1644586, EBI-2295402;
Similarity Belongs to the BI1 family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:19054355}; Multi-pass membrane protein {ECO:0000269|PubMed:19054355}.
Subunit Interacts (via C-terminus) with calmodulin, CYTB5-B and CYTB5-D. Interacts indirectly with FAH1 via CYTB5-D. {ECO:0000269|PubMed:17142482, ECO:0000269|PubMed:19054355, ECO:0000269|PubMed:19674971, ECO:0000269|PubMed:22635113}.
Tissue Specificity Expressed in root tips, root vasculature, flower tissues, including stamens and sepals, and in the base of siliques. Not detected in mature leaves. {ECO:0000269|PubMed:19674971}.

Identical and Related Proteins

Unique RefSeq proteins for LMP009899 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15238017 RefSeq NP_199523 247 BAX inhibitor 1

Identical Sequences to LMP009899 proteins

Reference Database Accession Length Protein Name
GI:15238017 GenBank AGF25160.1 247 Sequence 4 from patent US 8373022
GI:15238017 GenBank AGX79574.1 247 Sequence 58913 from patent US 8541208
GI:15238017 GenBank AGX95329.1 247 Sequence 70919 from patent US 8541208
GI:15238017 GenBank AGX97702.1 247 Sequence 75652 from patent US 8541208
GI:15238017 GenBank AGY03412.1 247 Sequence 87023 from patent US 8541208
GI:15238017 GenBank AGY09760.1 247 Sequence 99621 from patent US 8541208

Related Sequences to LMP009899 proteins

Reference Database Accession Length Protein Name
GI:15238017 EMBL CBG18110.1 247 unnamed protein product [Arabidopsis thaliana]
GI:15238017 EMBL CBG03941.1 247 unnamed protein product [Arabidopsis thaliana]
GI:15238017 GenBank AGX95324.1 247 Sequence 70909 from patent US 8541208
GI:15238017 GenBank AGX97697.1 247 Sequence 75642 from patent US 8541208
GI:15238017 GenBank AGY03407.1 247 Sequence 87013 from patent US 8541208
GI:15238017 GenBank AGY09755.1 247 Sequence 99611 from patent US 8541208