Gene/Proteome Database (LMPD)

LMPD ID
LMP009959
Gene ID
834284
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
BRI1 kinase inhibitor 1
Gene Symbol
BKI1
Synonyms
BRI1 kinase inhibitor 1; MJB21.13; MJB21_13
Alternate Names
BRI1 kinase inhibitor 1
Chromosome
5

Proteins

BRI1 kinase inhibitor 1
Refseq ID NP_568610
Protein GI 18422246
UniProt ID Q9FMZ0
mRNA ID NM_123639
Length 337
RefSeq Status REVIEWED
METNLQQVKNSSQTFSEKQNPKQEASPSPISSTCSSPSHDFSFTISLQPLSSSSKHISPTLRSPSKTTSSYQQTDPFAVDLSPADEIFFHGHLLPLHLLSHLPVSPRTSTGSYNDGFTLPVKDILPDQPTNNNNNTENAITNISTEAKDDNTEDKAEGEIRVKTKPIKSFSLFGLSKWRKGFESNEREQENKIKKPMSLDLSHAVKKYIRMLFQKRGNGTQFWNRRQTSSYSFSSSLMGPNGNSKTMINGSYNKRDLIRGRRGELFSAPASMRTSPTNSGHLRVSTAGLSSSSGSTSSSSSDSTMEELQAAIQAAIAHCKNSSAVDRDDKVKDS

Gene Information

Entrez Gene ID
834284
Gene Name
BRI1 kinase inhibitor 1
Gene Symbol
BKI1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 IDA:TAIR C cytosol
GO:0005886 IDA:TAIR C plasma membrane
GO:0046982 IPI:TAIR F protein heterodimerization activity
GO:0009742 IEA:UniProtKB-KW P brassinosteroid mediated signaling pathway
GO:0006629 IEA:UniProtKB-KW P lipid metabolic process
GO:0010423 IMP:TAIR P negative regulation of brassinosteroid biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath04075 Plant hormone signal transduction
ko04075 Plant hormone signal transduction

Domain Information

InterPro Annotations

Accession Description

UniProt Annotations

Entry Information

Gene Name
BRI1 kinase inhibitor 1
Protein Entry
BKI1_ARATH
UniProt ID
Q9FMZ0
Species
Arabidopsis

Comments

Comment Type Description
Domain The c-terminal part (253-337) is necessary and sufficient for the interaction with BRI1.
Function Negative regulator of brassinosteroid signaling. When associated to the membrane, limits the interaction of BRI1 with BAK1 by binding to the kinase-inactive form of BRI1. {ECO:0000269|PubMed:16857903}.
Interaction Q9ZWC8:BRL1; NbExp=4; IntAct=EBI-1111615, EBI-590903;
Miscellaneous BRI1 is not required for BKI1 association with the plasma membrane, but the BRI1 kinase activity is necessary for the membrane release.
Ptm Phosphorylated on Tyr-211 in response to brassinosteroid perception, leading to its inactivation: once phosphorylated, displaced into the cytosol where it is inactive. {ECO:0000269|PubMed:16857903, ECO:0000269|PubMed:21289069}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:21289069}. Cytoplasm {ECO:0000269|PubMed:21289069}. Note=Once phosphorylated following brassinosteroid treatment, displaced from the plasma membrane into the cytosol where it is inactive.
Subunit Interacts (via C-terminus) with BRI1 (via kinase domain). {ECO:0000269|PubMed:16857903}.
Tissue Specificity Expressed in leaves, petioles, shoot apices, hypocotyls, roots and flowers. {ECO:0000269|PubMed:16857903}.

Identical and Related Proteins

Unique RefSeq proteins for LMP009959 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
18422246 RefSeq NP_568610 337 BRI1 kinase inhibitor 1

Identical Sequences to LMP009959 proteins

Reference Database Accession Length Protein Name
GI:18422246 DBBJ BAB10631.1 337 unnamed protein product [Arabidopsis thaliana]
GI:18422246 GenBank ACF04813.1 337 At5g42750 [Arabidopsis thaliana]
GI:18422246 GenBank AEP50945.1 337 Sequence 1 from patent US 8008542
GI:18422246 gnl TAIR 337 BRI1 kinase inhibitor 1 [Arabidopsis thaliana]
GI:18422246 SwissProt Q9FMZ0.1 337 RecName: Full=BRI1 kinase inhibitor 1 [Arabidopsis thaliana]

Related Sequences to LMP009959 proteins

Reference Database Accession Length Protein Name
GI:18422246 GenBank AAM64772.1 337 unknown [Arabidopsis thaliana]
GI:18422246 GenBank EFH40001.1 336 hypothetical protein ARALYDRAFT_494760 [Arabidopsis lyrata subsp. lyrata]
GI:18422246 RefSeq XP_002863742.1 336 hypothetical protein ARALYDRAFT_494760 [Arabidopsis lyrata subsp. lyrata]
GI:18422246 RefSeq XP_010442127.1 341 PREDICTED: BRI1 kinase inhibitor 1-like [Camelina sativa]
GI:18422246 RefSeq XP_010481951.1 342 PREDICTED: BRI1 kinase inhibitor 1-like [Camelina sativa]
GI:18422246 RefSeq XP_010494222.1 341 PREDICTED: BRI1 kinase inhibitor 1 [Camelina sativa]