Gene/Proteome Database (LMPD)

LMPD ID
LMP010041
Gene ID
825044
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
citrate synthase 2
Gene Symbol
CSY2
Synonyms
citrate synthase 2; CSY2
Alternate Names
citrate synthase 2
Chromosome
3
EC Number
2.3.3.16
Summary
Encodes a peroxisomal citrate synthase that is expressed throughout seedling and shoot development.
Orthologs
View orthologs and multiple alignments for CSY2

Proteins

citrate synthase 2
Refseq ID NP_191434
Protein GI 15231130
UniProt ID Q9LXS6
mRNA ID NM_115737
Length 514
RefSeq Status REVIEWED
MEISQRVKARLAVLTAHLAVSDTVGLEQVLPAIAPWCTSAHITAAPHGSLKGNLTIVDERTGKKYQVPVSEHGTVKAVDLKKITTGKDDKGLKLYDPGYLNTAPVRSSICYIDGDEGILRYRGYPIEELAESSTFIEVAYLLMYGNLPSQSQLADWEFTVSQHSAVPQGVLDIIQSMPHDAHPMGVLVSAMSALSIFHPDANPALSGQDIYKSKQVRDKQIVRILGKAPTIAAAAYLRTAGRPPVLPSANLSYSENFLYMLDSMGNRSYKPNPRLARVLDILFILHAEHEMNCSTAAARHLASSGVDVYTACAGAVGALYGPLHGGANEAVLKMLAEIGTAENIPDFIEGVKNRKRKMSGFGHRVYKNYDPRAKVIKKLADEVFSIVGRDPLIEVAVALEKAALSDEYFVKRKLYPNVDFYSGLIYRAMGFPPEFFTVLFAVPRMAGYLSHWRESLDDPDTRIMRPQQAYTGVWMRHYEPVRERTLSSDSDKDKFGQVSISNASRRRLAGSSAL

Gene Information

Entrez Gene ID
825044
Gene Name
citrate synthase 2
Gene Symbol
CSY2
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005777 IDA:TAIR C peroxisome
GO:0009506 IDA:TAIR C plasmodesma
GO:0004108 IGI:TAIR F citrate (Si)-synthase activity
GO:0044262 IEA:InterPro P cellular carbohydrate metabolic process
GO:0006635 IGI:TAIR P fatty acid beta-oxidation
GO:0006099 IEA:UniProtKB-UniPathway P tricarboxylic acid cycle

KEGG Pathway Links

KEGG Pathway ID Description
ath01210 2-Oxocarboxylic acid metabolism
ath01230 Biosynthesis of amino acids
ath01200 Carbon metabolism
ath00020 Citrate cycle (TCA cycle)

Domain Information

InterPro Annotations

Accession Description
IPR019810 Citrate synthase active site
IPR024176 Citrate synthase, bacterial-type
IPR002020 Citrate synthase-like
IPR016141 Citrate synthase-like, core
IPR016142 Citrate synthase-like, large alpha subdomain
IPR016143 Citrate synthase-like, small alpha subdomain

UniProt Annotations

Entry Information

Gene Name
citrate synthase 2
Protein Entry
CISY2_ARATH
UniProt ID
Q9LXS6
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA. {ECO:0000255|PROSITE-ProRule:PRU10117}.
Developmental Stage Expressed throughout seedling growth. {ECO:0000269|PubMed:15923350}.
Function Peroxisomal citrate synthase required for the fatty acid respiration in seedlings, citrate being exported from peroxisomes into mitochondria during respiration of triacylglycerol (TAG). Indeed, complete respiration requires the transfer of carbon in the form of citrate from the peroxisome to the mitochondria. {ECO:0000269|PubMed:15923350}.
Miscellaneous Citrate synthase is found in nearly all cells capable of oxidative metabolism.
Pathway Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.
Sequence Caution Sequence=BAD93857.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Similarity Belongs to the citrate synthase family. {ECO:0000305}.
Subcellular Location Peroxisome {ECO:0000269|PubMed:15923350}.
Tissue Specificity Widely expressed. Expressed throughout the shoot. Expressed in flower, silique, stem, cauline leaf, young leaf, mature leaf and senescent leaf. {ECO:0000269|PubMed:15923350}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010041 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15231130 RefSeq NP_191434 514 citrate synthase 2

Identical Sequences to LMP010041 proteins

Reference Database Accession Length Protein Name
GI:15231130 EMBL CAB88292.1 514 citrate synthase-like protein [Arabidopsis thaliana]
GI:15231130 GenBank AAU95420.1 514 At3g58750 [Arabidopsis thaliana]
GI:15231130 GenBank AAV59261.1 514 At3g58750 [Arabidopsis thaliana]
GI:15231130 GenBank ADL90075.1 514 Sequence 2 from patent US 7705204
GI:15231130 GenBank AEE79826.1 514 citrate synthase 2 [Arabidopsis thaliana]
GI:15231130 SwissProt Q9LXS6.1 514 RecName: Full=Citrate synthase 2, peroxisomal; Flags: Precursor [Arabidopsis thaliana]

Related Sequences to LMP010041 proteins

Reference Database Accession Length Protein Name
GI:15231130 GenBank EFH54497.1 514 hypothetical protein ARALYDRAFT_486329 [Arabidopsis lyrata subsp. lyrata]
GI:15231130 GenBank EOA26169.1 514 hypothetical protein CARUB_v10019607mg [Capsella rubella]
GI:15231130 RefSeq XP_002878238.1 514 hypothetical protein ARALYDRAFT_486329 [Arabidopsis lyrata subsp. lyrata]
GI:15231130 RefSeq XP_006293271.1 514 hypothetical protein CARUB_v10019607mg [Capsella rubella]
GI:15231130 RefSeq XP_010504835.1 514 PREDICTED: citrate synthase 2, peroxisomal-like [Camelina sativa]
GI:15231130 RefSeq XP_010516532.1 514 PREDICTED: citrate synthase 2, peroxisomal [Camelina sativa]