Gene/Proteome Database (LMPD)

LMPD ID
LMP010049
Gene ID
839343
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
clathrin coat assembly protein AP180
Gene Symbol
AT1G05020
Synonyms
T7A14.11; T7A14_11
Alternate Names
clathrin coat assembly protein AP180
Chromosome
1

Proteins

clathrin coat assembly protein AP180
Refseq ID NP_563726
Protein GI 18390470
UniProt ID Q9ZVN6
mRNA ID NM_100381
Length 653
RefSeq Status REVIEWED
MPSKLKKAIGAVKDQTSISLAKVANGATGGGDLTTLEVAILKATSHDEEVPIDDRLVTEILGIISSKKSHAASCAAAIGRRIGRTRNWIVALKSLVLVLRIFQDGDPYFPREVLHAMKRGAKILNLSSFRDDSNSCPWDFTAFVRTFALYLDERLDCFLTGKLQRRYTNREQTGRISTNSTTRSRFNPKAGIKSHEPAVRDMKPVMLLDKITYWQKLLDRAIATRPTGDAKANRLVKMSLYAVMQESFDLYRDISDGLALLLDSFFHLQYQSCINAFQACVRASKQFEELNAFYDLSKSIGIGRTSEYPSIQKISLELLETLQEFLKDQSSFPASSGLYPSPNSFLPPPPSSKDSAVSSSLDFGDSTIDTSERYSDYGSFRSTSLEDLMSRTEAGTSSPPMSCHSEPYGGGRDDPNGNNFDTVSTKSLPNNPSVSASNLILDLLSLDDVSNTAEAEDVEDKKKQDDSKAETFDPWEALMLRDDPKKKIETIEEEPSTAEDHQRDSGNWLLALEETATQVQGNNSMAIVPFGLDDPMPAFQAATDQYNPFLEEPVAQLATAGEPMITFGGLALTGFQPEPTFQVNVPDDFEPSSTPTFKATETLPMKCDPFTTFESFGFGETFSENGGVNQQSVLQEQQIWLQNQKKIIAKHLS

Gene Information

Entrez Gene ID
839343
Gene Name
clathrin coat assembly protein AP180
Gene Symbol
AT1G05020
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IEA:UniProtKB-KW C Golgi apparatus
GO:0030118 IEA:InterPro C clathrin coat
GO:0005905 IEA:UniProtKB-KW C coated pit
GO:0031410 IEA:UniProtKB-KW C cytoplasmic vesicle
GO:0005545 IEA:InterPro F 1-phosphatidylinositol binding
GO:0048268 IEA:InterPro P clathrin coat assembly
GO:0006897 IEA:UniProtKB-KW P endocytosis
GO:0015031 IEA:UniProtKB-KW P protein transport

Domain Information

InterPro Annotations

Accession Description
IPR011417 AP180 N-terminal homology (ANTH) domain
IPR008942 ENTH_VHS
IPR013809 Epsin-like_N
IPR014712 Phosphoinositide-binding clathrin adaptor, domain 2

UniProt Annotations

Entry Information

Gene Name
clathrin coat assembly protein AP180
Protein Entry
AP180_ARATH
UniProt ID
Q9ZVN6
Species
Arabidopsis

Comments

Comment Type Description
Function Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Binding of AP180 to clathrin triskelia promotes their assembly into 70-90 nm coats cages. {ECO:0000269|PubMed:15054111}.
Interaction Q8LPK4:ALPHAC-AD; NbExp=2; IntAct=EBI-2366853, EBI-2366827;
Similarity Contains 1 ENTH (epsin N-terminal homology) domain. {ECO:0000255|PROSITE-ProRule:PRU00243}.
Subcellular Location Membrane, clathrin-coated pit {ECO:0000250}. Golgi apparatus {ECO:0000250}. Cytoplasmic vesicle, clathrin- coated vesicle {ECO:0000250}. Note=Colocalized with clathrin in the Golgi area. {ECO:0000250}.
Subunit Interacts with ALPHAC-AD and clathrin. {ECO:0000269|PubMed:15054111}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010049 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
18390470 RefSeq NP_563726 653 clathrin coat assembly protein AP180

Identical Sequences to LMP010049 proteins

Reference Database Accession Length Protein Name
GI:18390470 DBBJ BAC42127.1 653 putative clathrin protein [Arabidopsis thaliana]
GI:18390470 GenBank AAC97997.1 653 Similar to clathrin assembly protein gb|X68878 (AP180) from Rattus norvegicus. EST gb|W43552 comes from this gene [Arabidopsis thaliana]
GI:18390470 GenBank AAO50717.1 653 putative clathrin [Arabidopsis thaliana]
GI:18390470 GenBank AEE27780.1 653 clathrin coat assembly protein AP180 [Arabidopsis thaliana]
GI:18390470 SwissProt Q9ZVN6.1 653 RecName: Full=Clathrin coat assembly protein AP180; Short=At-AP180; AltName: Full=Clathrin coat-associated protein AP180 [Arabidopsis thaliana]

Related Sequences to LMP010049 proteins

Reference Database Accession Length Protein Name
GI:18390470 GenBank EFH68519.1 643 hypothetical protein ARALYDRAFT_887680 [Arabidopsis lyrata subsp. lyrata]
GI:18390470 GenBank EOA39863.1 655 hypothetical protein CARUB_v10008537mg [Capsella rubella]
GI:18390470 RefSeq XP_002892260.1 643 hypothetical protein ARALYDRAFT_887680 [Arabidopsis lyrata subsp. lyrata]
GI:18390470 RefSeq XP_006306965.1 655 hypothetical protein CARUB_v10008537mg [Capsella rubella]
GI:18390470 RefSeq XP_010484563.1 660 PREDICTED: LOW QUALITY PROTEIN: clathrin coat assembly protein AP180-like [Camelina sativa]
GI:18390470 RefSeq XP_010457575.1 652 PREDICTED: clathrin coat assembly protein AP180-like [Camelina sativa]