Gene/Proteome Database (LMPD)

LMPD ID
LMP010050
Gene ID
818918
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
putative clathrin interactor EPSIN 2
Gene Symbol
AT2G43160
Synonyms
F14B2.10
Alternate Names
putative clathrin interactor EPSIN 2
Chromosome
2

Proteins

putative clathrin interactor EPSIN 2
Refseq ID NP_850386
Protein GI 30689266
UniProt ID Q67YI9
mRNA ID NM_180055
Length 895
RefSeq Status REVIEWED
MKKVFGQTVRDLKREVNKKVLKVPGVEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMVVIWKRLSDTGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGSNVRKKSQSLVALVNDKERIAEVRQKAAANRDKYRSSAPGGMYKPSGGYGDKYDYGSRDEERSSYGREREYGYRDDDRNSRDGDRHSRDSEDRYGRDGNRDDDYRGRSRSVDNYGSRGRSSEREREDDGHSSSRGSGARADDNSQDGRGGLQRKFSEQNIGAPPSYEEAVSDSRSPVYSERDGGETPQVTAPGAASPPPPQVAAPEAASPPTGTNTANTTATFVNESPSQKVETFDEFDPRSAFSAGPPAYASTDGVTAPPTVTSMSAPTTSNSVEMDLLGSLADVFSSNALAIVPADSIYVETNGQANAGPAPSFSTSQPSTQSFDDPFGDSPFKAFTSTDTDSTPQQNFGASFQPPPPAFTSEVSHPDTAHNFGFGDSFSAVANPDPASQNVQPPSNSPGFPQEQFATSQSGIDILAGILPPSGPPVQSGPSIPTSQFPPSGNNMYEGFHSQPPVSTAPNLPGQTPFGQAVQPYNMVPHSQNMTGAMPFNSGGFMHQPGSQTPYSTPSGPAGQFMAHQGHGMPPSHGPQRTQSGPVTLQGNNNVMGDMFSQATPNSLTSSSSHPDLTPLTGAIEIVPPPQKKFEPKSSVWADTLSRGLVNFNISGSKTNPLADIGVDFEAINRREKRLEKQTNTPATSTINMGKAMGSGTGLGRSGATAMRPPPNPMTGSGMPMGGGMGVGSYGGMNQNQPMGMGMGAGMNQNQPMGMGMGPGMNMNMNMGGYGQGYPMQPQNPGMVPSPNMPGNNYNPMMGQGGYNPQQSYGGGYR
putative clathrin interactor EPSIN 2
Refseq ID NP_973675
Protein GI 42571203
UniProt ID Q67YI9
mRNA ID NM_201946
Length 895
RefSeq Status REVIEWED
Protein sequence is identical to GI:30689266 (mRNA isoform)
putative clathrin interactor EPSIN 2
Refseq ID NP_850387
Protein GI 30689274
UniProt ID Q67YI9
mRNA ID NM_180056
Length 895
RefSeq Status REVIEWED
Protein sequence is identical to GI:30689266 (mRNA isoform)
putative clathrin interactor EPSIN 2
Refseq ID NP_001031535
Protein GI 79324901
UniProt ID Q67YI9
mRNA ID NM_001036458
Length 646
RefSeq Status REVIEWED
MKKVFGQTVRDLKREVNKKVLKVPGVEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMVVIWKRLSDTGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGSNVRKKSQSLVALVNDKERIAEVRQKAAANRDKYRSSAPGGMYKPSGGYGDKYDYGSRDEERSSYGREREYGYRDDDRNSRDGDRHSRDSEDRYGRDGNRDDDYRGRSRSVDNYGSRGRSSEREREDDGHSSSRGSGARADDNSQDGRGGLQRKFSEQNIGAPPSYEEAVSDSRSPVYSERDGGETPQVTAPGAASPPPPQVAAPEAASPPTGTNTANTTATFVNESPSQKVETFDEFDPRSAFSAGPPAYASTDGVTAPPTVTSMSAPTTSNSVEMDLLGSLADVFSSNALAIVPADSIYVETNGQANAGPAPSFSTSQPSTQSFDDPFGDSPFKAFTSTDTDSTPQQNFGASFQPPPPAFTSEVSHPDTAHNFGFGDSFSAVANPDPASQNVQPPSNSPGFPQEQFATSQSGIDILAGILPPSGPPVQSGPSIPTSQFPPSGNNMYEGFHSQPPVSTAPNLPGQTPFGQAVQPYNMVPHSQNMTGAMPFNSGGFMHQPGSQTPYSTPSGPAGQFMALA

Gene Information

Entrez Gene ID
818918
Gene Name
putative clathrin interactor EPSIN 2
Gene Symbol
AT2G43160
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IDA:UniProtKB C Golgi apparatus
GO:0031410 IEA:UniProtKB-KW C cytoplasmic vesicle
GO:0005886 IDA:TAIR C plasma membrane
GO:0005774 IDA:TAIR C vacuolar membrane
GO:0030276 IDA:UniProtKB F clathrin binding
GO:0005543 IDA:UniProtKB F phospholipid binding
GO:0015031 IEA:UniProtKB-KW P protein transport

KEGG Pathway Links

KEGG Pathway ID Description
ath04144 Endocytosis
ko04144 Endocytosis

Domain Information

InterPro Annotations

Accession Description
IPR008942 ENTH_VHS
IPR013809 Epsin-like_N

UniProt Annotations

Entry Information

Gene Name
putative clathrin interactor EPSIN 2
Protein Entry
EPN2_ARATH
UniProt ID
Q67YI9
Species
Arabidopsis

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q67YI9-1; Sequence=Displayed; Name=2; IsoId=Q67YI9-2; Sequence=VSP_039700, VSP_039701;
Domain The ENTH domain is required for PtdIns(3)P affinity and EPSIN2 subcellular location.
Function May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly (By similarity). Binds to membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(3)P). Plays an important role in protein trafficking. {ECO:0000250, ECO:0000269|PubMed:17277094}.
Sequence Caution Sequence=AAC64305.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAC64306.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the epsin family. {ECO:0000305}.
Similarity Contains 1 ENTH (epsin N-terminal homology) domain. {ECO:0000255|PROSITE-ProRule:PRU00243}.
Subcellular Location Golgi apparatus {ECO:0000269|PubMed:17277094}. Cytoplasmic vesicle, clathrin- coated vesicle {ECO:0000269|PubMed:17277094}. Note=Localizes also to a novel cellular compartment, the 'delta compartment', characterized by colocalization of EPSIN2 and DELTA-ADR.
Subunit Interacts with clathrin, VTI12, DELTA-ADR and ALPHA-ADR. {ECO:0000269|PubMed:17277094}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010050 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
30689266 RefSeq NP_850386 895 putative clathrin interactor EPSIN 2
79324901 RefSeq NP_001031535 646 putative clathrin interactor EPSIN 2

Identical Sequences to LMP010050 proteins

Reference Database Accession Length Protein Name
GI:79324901 DBBJ BAD44158.1 646 unnamed protein product [Arabidopsis thaliana]
GI:30689266 DBBJ BAF02079.1 895 hypothetical protein [Arabidopsis thaliana]
GI:30689266 GenBank AEC10216.1 895 putative clathrin interactor EPSIN 2 [Arabidopsis thaliana]
GI:30689266 GenBank AEC10217.1 895 putative clathrin interactor EPSIN 2 [Arabidopsis thaliana]
GI:30689266 GenBank AEC10218.1 895 putative clathrin interactor EPSIN 2 [Arabidopsis thaliana]
GI:79324901 GenBank AEC10219.1 646 putative clathrin interactor EPSIN 2 [Arabidopsis thaliana]
GI:30689266 GenBank AHE22445.1 895 Sequence 80 from patent US 8575421
GI:79324901 GenBank AHE22446.1 646 Sequence 82 from patent US 8575421
GI:30689266 SwissProt Q67YI9.1 895 RecName: Full=Clathrin interactor EPSIN 2; AltName: Full=EPSIN-related 2 [Arabidopsis thaliana]

Related Sequences to LMP010050 proteins

Reference Database Accession Length Protein Name
GI:30689266 DBBJ BAD94036.1 895 hypothetical protein [Arabidopsis thaliana]
GI:79324901 DBBJ BAD93910.1 895 hypothetical protein [Arabidopsis thaliana]
GI:79324901 DBBJ BAD93914.1 895 hypothetical protein [Arabidopsis thaliana]
GI:30689266 DBBJ BAF01674.1 895 hypothetical protein [Arabidopsis thaliana]
GI:30689266 GenBank AAK91471.1 895 At2g43170/F14B2.11 [Arabidopsis thaliana]
GI:30689266 GenBank AAN72258.1 895 At2g43170/F14B2.11 [Arabidopsis thaliana]
GI:79324901 GenBank AEC10216.1 895 putative clathrin interactor EPSIN 2 [Arabidopsis thaliana]
GI:30689266 GenBank AHE22444.1 895 Sequence 78 from patent US 8575421
GI:79324901 GenBank AHE22445.1 895 Sequence 80 from patent US 8575421
GI:30689266 GenBank AHE22447.1 895 Sequence 84 from patent US 8575421
GI:79324901 RefSeq NP_850387.1 895 putative clathrin interactor EPSIN 2 [Arabidopsis thaliana]
GI:79324901 SwissProt Q67YI9.1 895 RecName: Full=Clathrin interactor EPSIN 2; AltName: Full=EPSIN-related 2 [Arabidopsis thaliana]