Gene/Proteome Database (LMPD)

LMPD ID
LMP010057
Gene ID
831216
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
cycloartenol-c-24-methyltransferase
Gene Symbol
SMT1
Synonyms
CEPHALOPOD; CPH; MSH12.18; MSH12_18; SAM:CYCLOARTENOL-C24-METHYLTRANSFERASE; SMT1; sterol methyltransferase 1
Alternate Names
cycloartenol-c-24-methyltransferase
Chromosome
5
EC Number
2.1.1.41

Proteins

cycloartenol-c-24-methyltransferase
Refseq ID NP_001078579
Protein GI 145334395
UniProt ID Q9LM02
mRNA ID NM_001085110
Length 336
RefSeq Status REVIEWED
MDLASNLGGKIDKSDVLTAVEKYEQYHVFHGGNEEERKANYTDMVNKYYDLATSFYEYGWGESFHFAQRWKGESLRESIKRHEHFLALQLGIQPGQKVLDVGCGIGGPLREIARFSNSVVTGLNNNEYQITRGKELNRLAGVDKTCNFVKADFMKMPFPENSFDAVYAIEATCHAPDAYGCYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAEHQKIKGEIEIGDGLPDIRLTTKCLEALKQAGFEVIWEKDLAKDSPVPWYLPLDKNHFSLSSFRLTAVGRFITKNMVKILEYIRLAPQGSQRVSNFLEQAAEGLVDGGRREIFTPMYFFLARKPE
cycloartenol-c-24-methyltransferase
Refseq ID NP_196875
Protein GI 15240691
UniProt ID Q9LM02
mRNA ID NM_121374
Length 336
RefSeq Status REVIEWED
Protein sequence is identical to GI:145334395 (mRNA isoform)

Gene Information

Entrez Gene ID
831216
Gene Name
cycloartenol-c-24-methyltransferase
Gene Symbol
SMT1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IDA:TAIR C endoplasmic reticulum
GO:0009506 IDA:TAIR C plasmodesma
GO:0005773 IDA:TAIR C vacuole
GO:0003838 IDA:TAIR F sterol 24-C-methyltransferase activity
GO:0009793 IMP:TAIR P embryo development ending in seed dormancy
GO:0016126 IMP:TAIR P sterol biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath01110 Biosynthesis of secondary metabolites
ath00100 Steroid biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR013216 Methyltransferase type 11
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
IPR013705 Sterol methyltransferase C-terminal

UniProt Annotations

Entry Information

Gene Name
cycloartenol-c-24-methyltransferase
Protein Entry
SMT1_ARATH
UniProt ID
Q9LM02
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity S-adenosyl-L-methionine + 5-alpha-cholesta- 8,24-dien-3-beta-ol = S-adenosyl-L-homocysteine + 24-methylene-5- alpha-cholest-8-en-3-beta-ol.
Function Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of cycloartenol to form 24-methylene cycloartenol.
Pathway Steroid biosynthesis; sterol biosynthesis.
Similarity Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family. {ECO:0000255|PROSITE-ProRule:PRU01022}.
Tissue Specificity Highly expressed in vascular tissue, mature leaves and in regions undergoing cellular expansion.

Identical and Related Proteins

Unique RefSeq proteins for LMP010057 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
145334395 RefSeq NP_001078579 336 cycloartenol-c-24-methyltransferase

Identical Sequences to LMP010057 proteins

Reference Database Accession Length Protein Name
GI:145334395 GenBank ACW98080.1 336 Sequence 18590 from patent US 7569389
GI:145334395 GenBank ACW98155.1 336 Sequence 18692 from patent US 7569389
GI:145334395 GenBank ACW99961.1 336 Sequence 21159 from patent US 7569389
GI:145334395 GenBank ADT60073.1 336 Sequence 1036 from patent US 7847156
GI:145334395 gnl TAIR 336 cycloartenol-c-24-methyltransferase [Arabidopsis thaliana]
GI:145334395 gnl TAIR 336 cycloartenol-c-24-methyltransferase [Arabidopsis thaliana]

Related Sequences to LMP010057 proteins

Reference Database Accession Length Protein Name
GI:145334395 GenBank ACW87330.1 378 Sequence 3983 from patent US 7569389
GI:145334395 GenBank ACW87628.1 366 Sequence 4398 from patent US 7569389
GI:145334395 GenBank ACW88500.1 358 Sequence 5587 from patent US 7569389
GI:145334395 GenBank ACW97963.1 378 Sequence 18429 from patent US 7569389
GI:145334395 GenBank ACW98079.1 358 Sequence 18589 from patent US 7569389
GI:145334395 GenBank ACW98154.1 366 Sequence 18691 from patent US 7569389