Gene/Proteome Database (LMPD)

LMPD ID
LMP010062
Gene ID
821788
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
protein PATHOGEN AND CIRCADIAN CONTROLLED 1
Gene Symbol
PCC1
Synonyms
PATHOGEN AND CIRCADIAN CONTROLLED 1; PCC1
Alternate Names
protein PATHOGEN AND CIRCADIAN CONTROLLED 1
Chromosome
3
Summary
Encodes a member of a novel 6 member Arabidopsis gene family. Expression of PCC1 is regulated by the circadian clock and is upregulated in response to both virulent and avirulent strains of Pseudomonas syringae pv. tomato.
Orthologs
View orthologs and multiple alignments for PCC1

Proteins

protein PATHOGEN AND CIRCADIAN CONTROLLED 1
Refseq ID NP_566702
Protein GI 18403306
UniProt ID Q94C26
mRNA ID NM_113121
Length 81
RefSeq Status REVIEWED
MNQSAQNYFSVQKPSETSSGPYTSPPPIGYPTRDAVVGDPPAAAVETNSKGVNPEAIMSCFSTCMECIFCCGVCSSLCTSE

Gene Information

Entrez Gene ID
821788
Gene Name
protein PATHOGEN AND CIRCADIAN CONTROLLED 1
Gene Symbol
PCC1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016020 TAS:UniProtKB C membrane
GO:0005886 IDA:TAIR C plasma membrane
GO:0009738 IEA:UniProtKB-KW P abscisic acid-activated signaling pathway
GO:0071494 IDA:UniProtKB P cellular response to UV-C
GO:0007623 IDA:UniProtKB P circadian rhythm
GO:0006952 IEA:UniProtKB-KW P defense response
GO:0055088 IMP:UniProtKB P lipid homeostasis
GO:0006629 IEA:UniProtKB-KW P lipid metabolic process
GO:1902290 IMP:UniProtKB P positive regulation of defense response to oomycetes
GO:0010513 IMP:UniProtKB P positive regulation of phosphatidylinositol biosynthetic process
GO:1900150 IMP:UniProtKB P regulation of defense response to fungus
GO:0046890 IMP:UniProtKB P regulation of lipid biosynthetic process
GO:2000028 IMP:UniProtKB P regulation of photoperiodism, flowering
GO:0009737 IMP:UniProtKB P response to abscisic acid
GO:0009617 IDA:UniProtKB P response to bacterium
GO:0009863 IMP:UniProtKB P salicylic acid mediated signaling pathway

Domain Information

InterPro Annotations

Accession Description
IPR028144 Cysteine-rich transmembrane CYSTM domain

UniProt Annotations

Entry Information

Gene Name
protein PATHOGEN AND CIRCADIAN CONTROLLED 1
Protein Entry
PCC1_ARATH
UniProt ID
Q94C26
Species
Arabidopsis

Comments

Comment Type Description
Developmental Stage Low expression after germination followed by an abrupt level increase in 10-days old seedlings. Accumulates in senescent leaves. {ECO:0000269|PubMed:19781011}.
Disruption Phenotype Late flowering and defective in UV-C light acceleration of flowering. Strong reduction of FLOWERING LOCUS T (FT) expression. Hypersensitivity to abscisic acid (ABA) and alterations in polar lipid contents and their corresponding fatty acids; reduced levels of phosphatidylinositol (PI) and of 18:0, but increased levels of 18:2 and 18:3 polar lipids. Increased susceptibility to the hemi-biotrophic oomycete pathogen Phytophthora brassicae but enhanced resistance to the necrotrophic fungal pathogen Botrytis cinerea. {ECO:0000269|PubMed:19781011, ECO:0000269|PubMed:23833195}.
Function Modulates resistance against pathogens including oomycetes (e.g. Hyaloperonospora parasitica and Phytophthora brassicae) and fungi (e.g. Phytophthora brassicae). Controls the abscisic acid-mediated (ABA) signaling pathways. Regulator of the flowering time in response to stress (e.g. UV-C). Regulates polar lipid content; promotes phosphatidylinositol (PI) and 18:0 but prevents 18:2 and 18:3 polar lipids accumulation. {ECO:0000269|PubMed:14614626, ECO:0000269|PubMed:19781011, ECO:0000269|PubMed:23833195}.
Induction Rapidly up-regulated after pathogen exposure (e.g. avirulent and virulent Pseudomonas syringae pv. tomato) in a salicylic acid (SA) defense-signaling pathway-dependent manner. Circadian-regulation with accumulation during the light period, peaks of expression at the end of the day, and low levels during the dark period. Up-regulated by UV-C light through a SA-dependent process and in a CONSTANS- (CO) dependent manner. {ECO:0000269|PubMed:14614626, ECO:0000269|PubMed:19781011}.
Sequence Caution Sequence=BAB03071.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the CYSTM1 family. {ECO:0000305}.
Subcellular Location Cell membrane {ECO:0000305|PubMed:19933165}; Single-pass membrane protein {ECO:0000269|PubMed:19933165}.
Tissue Specificity Expressed at very low levels in seedlings and petioles, and at higher levels in leaves. Also present in phloem sap. {ECO:0000269|PubMed:19781011, ECO:0000269|PubMed:22442409}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010062 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
18403306 RefSeq NP_566702 81 protein PATHOGEN AND CIRCADIAN CONTROLLED 1

Identical Sequences to LMP010062 proteins

Reference Database Accession Length Protein Name
GI:18403306 DBBJ BAH19603.1 81 AT3G22231 [Arabidopsis thaliana]
GI:18403306 DBBJ BAH20414.1 81 AT3G22231 [Arabidopsis thaliana]
GI:18403306 GenBank AAO11584.1 81 At3g22240/MMP21_1 [Arabidopsis thaliana]
GI:18403306 GenBank ABT05631.1 81 Sequence 47 from patent US 7217864
GI:18403306 GenBank AEE76608.1 81 pathogen and circadian controlled 1 [Arabidopsis thaliana]
GI:18403306 SwissProt Q94C26.1 81 RecName: Full=Cysteine-rich and transmembrane domain-containing protein PCC1; AltName: Full=Protein PATHOGEN AND CIRCADIAN CONTROLLED 1 [Arabidopsis thaliana]

Related Sequences to LMP010062 proteins

Reference Database Accession Length Protein Name
GI:18403306 DBBJ BAC43711.1 71 unknown protein [Arabidopsis thaliana]
GI:18403306 GenBank AAL32880.1 71 Unknown protein [Arabidopsis thaliana]
GI:18403306 GenBank AAM10178.1 71 unknown protein [Arabidopsis thaliana]
GI:18403306 GenBank AEE76609.1 71 uncharacterized protein AT3G22235 [Arabidopsis thaliana]
GI:18403306 RefSeq NP_001154638.1 71 uncharacterized protein [Arabidopsis thaliana]
GI:18403306 RefSeq NP_850623.4 71 uncharacterized protein [Arabidopsis thaliana]