Gene/Proteome Database (LMPD)

LMPD ID
LMP010068
Gene ID
817435
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
cytochrome P450 710A4
Gene Symbol
CYP710A4
Synonyms
cytochrome P450; F8N16.15; F8N16_15; family 710; polypeptide 4; subfamily A
Alternate Names
cytochrome P450 710A4
Chromosome
2
EC Number
1.14.-.-
Summary
member of CYP710A
Orthologs
View orthologs and multiple alignments for CYP710A4

Proteins

cytochrome P450 710A4
Refseq ID NP_180452
Protein GI 15226976
UniProt ID Q9ZV28
mRNA ID NM_128445
Length 493
RefSeq Status REVIEWED
MVSSVSLFASLTPYLVSALLLFLLLEQLFYRVKKRNLPGPLFVFPIIGNVVALIRDPTSFWDKQSAMADTSVGLSVNYLIGKFIIYIKDAELSNKVLSNIRPDAFQLTGHPFGKKLFGDHSLIFMFGEDHKSVRRQVAPNFTRKPLSAYSSLQQIVILRHLRQWEESFSSGSRPVSMRQLIRELNLETSQTVFVGPYLDKEVKKTICDDYSLLTLGTMAIPIDLPGFTFGEARQAVSRLVNTMSVCVGKSKAKMAAGENPTCLVDFWTHSIIEENPPPPHSKDKEISCVLVDFMFASQDASTSSLLWAVVMLESEPEVLRRVREDVARFWSSESNELITADQLAEMKYTRAVAREVLRYRPPASMIPHVAVSDFRLTESYTIPKGTIVFPSLFDASFQGFTEPDRFDPDRFSETRQEDEVFKRNFLTFGNGSHQCVGQRYAMNHLVLFIAMFSSMFDFKRVRSDGCDDIVHIPTMSPKDGCTVFLSSRLVTSP

Gene Information

Entrez Gene ID
817435
Gene Name
cytochrome P450 710A4
Gene Symbol
CYP710A4
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0000249 IDA:UniProtKB F C-22 sterol desaturase activity
GO:0020037 IEA:InterPro F heme binding
GO:0005506 IEA:InterPro F iron ion binding
GO:0004497 IEA:UniProtKB-KW F monooxygenase activity
GO:0016126 IEA:UniProtKB-UniPathway P sterol biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath01110 Biosynthesis of secondary metabolites
ath00100 Steroid biosynthesis
ko00100 Steroid biosynthesis

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-2541 plant sterol biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR001128 Cytochrome P450
IPR002401 Cytochrome P450, E-class, group I
IPR017972 Cytochrome P450, conserved site

UniProt Annotations

Entry Information

Gene Name
cytochrome P450 710A4
Protein Entry
C7104_ARATH
UniProt ID
Q9ZV28
Species
Arabidopsis

Comments

Comment Type Description
Cofactor Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
Function Required to form the C-22 double bond in the sterol side chain. Possesses C-22 desaturase activity toward beta-sitosterol and produces stigmasterol. {ECO:0000269|PubMed:17909855}.
Miscellaneous Plants overexpressing CYP710A4 show higher levels of stigmasterol and lower levels of beta-sitosterol than the wild- type.
Pathway Steroid biosynthesis; sterol biosynthesis.
Sequence Caution Sequence=BX820851; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
Similarity Belongs to the cytochrome P450 family. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010068 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15226976 RefSeq NP_180452 493 cytochrome P450 710A4

Identical Sequences to LMP010068 proteins

Reference Database Accession Length Protein Name
GI:15226976 EMBL CBF74383.1 493 unnamed protein product [Arabidopsis thaliana]
GI:15226976 EMBL CBU96631.1 493 unnamed protein product [Arabidopsis thaliana]
GI:15226976 GenBank ACX18382.1 493 Sequence 46195 from patent US 7569389
GI:15226976 GenBank AEC08182.1 493 cytochrome P450 710A4 [Arabidopsis thaliana]
GI:15226976 GenBank AGX64059.1 493 Sequence 28222 from patent US 8541208
GI:15226976 SwissProt Q9ZV28.1 493 RecName: Full=Cytochrome P450 710A1; AltName: Full=C-22 sterol desaturase [Arabidopsis thaliana]

Related Sequences to LMP010068 proteins

Reference Database Accession Length Protein Name
GI:15226976 EMBL CBF74381.1 493 unnamed protein product [Arabidopsis thaliana]
GI:15226976 EMBL CBU96630.1 493 unnamed protein product [Arabidopsis thaliana]
GI:15226976 GenBank ACX18379.1 493 Sequence 46191 from patent US 7569389
GI:15226976 GenBank AEC08181.1 493 cytochrome P450 710A3 [Arabidopsis thaliana]
GI:15226976 gnl TIGR 493 putative cytochrome P450 [Arabidopsis thaliana]
GI:15226976 RefSeq NP_180451.1 493 cytochrome P450 710A3 [Arabidopsis thaliana]