Gene/Proteome Database (LMPD)

LMPD ID
LMP010082
Gene ID
839347
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
cytochrome P450, family 86, subfamily A, polypeptide 4
Gene Symbol
CYP86A4
Synonyms
cytochrome P450; F22L4.14; F22L4_14; family 86; polypeptide 4; subfamily A
Alternate Names
cytochrome P450, family 86, subfamily A, polypeptide 4
Chromosome
1
EC Number
1.14.14.1
Summary
Encodes a member of the CYP86A subfamily of cytochrome p450 genes. Expressed significantly at highest level in mature stems and flowers.
Orthologs
View orthologs and multiple alignments for CYP86A4

Proteins

cytochrome P450, family 86, subfamily A, polypeptide 4
Refseq ID NP_171666
Protein GI 15223436
UniProt ID Q9LMM1
mRNA ID NM_100042
Length 554
RefSeq Status REVIEWED
MEISNAMLLVAIVTGYWLWFKRISRWLKGPRVWPLLGSLPGLIEQRDRMHEWITENLRACGGTYQTCIFAVPFLAKKQGLVTVTCDPKNLEHMLKTRFDNYPKGPTWQSVFHDLLGQGIFNSDGDTWLFQRKTAALEFTTRTLRQAMGRWVNRGIKLRFCPILATAQDNAEPVDLQDLILRLTFDNICGLAFGKDTRTCAPGLPENGFASAFDRATEASLQRFIIPKFMWKLKKWLGLGLEVSLSRSLGEIDEYLAAVINTRKQELMSQQESGTHQRHDDLLSRFMMKKTESYSDTFLQHVALNFILAGRDTSSVALSWFFWLITMHPTVEDKIVREICSVLIETRGTDDVASWTEEPLGFDEIDRLVYLKAAISETLRLYPSVPEDSKHVENDDVLPDGTFVPAGSSVTYSIYAAGRMKSTWGEDCLEFNPERWISPIDGKFINHDQYRFVAFNAGPRICLGKDLAYLQMKTIAAAVLLRHRLTVVPGHKVEQKMSLTLFMKNGLLVNLYKRDLQGIIKSLVVKKSDGVSNGQCNGVIGEGVAVYLNTGVAVV

Gene Information

Entrez Gene ID
839347
Gene Name
cytochrome P450, family 86, subfamily A, polypeptide 4
Gene Symbol
CYP86A4
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0018685 IDA:TAIR F alkane 1-monooxygenase activity
GO:0070330 IEA:UniProtKB-EC F aromatase activity
GO:0020037 IEA:InterPro F heme binding
GO:0005506 IEA:InterPro F iron ion binding
GO:0006631 IDA:TAIR P fatty acid metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ath00073 Cutin, suberine and wax biosynthesis
ko00073 Cutin, suberine and wax biosynthesis
ath01100 Metabolic pathways

Domain Information

InterPro Annotations

Accession Description
IPR001128 Cytochrome P450
IPR002401 Cytochrome P450, E-class, group I
IPR017972 Cytochrome P450, conserved site

UniProt Annotations

Entry Information

Gene Name
cytochrome P450, family 86, subfamily A, polypeptide 4
Protein Entry
C86A4_ARATH
UniProt ID
Q9LMM1
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.
Cofactor Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
Disruption Phenotype No visible phenotype under normal growth conditions, but mutant plants have reduced content of the flower polyesters 16-hydroxypalmitate, 10,16-dihydroxypalmitate and 1,16- hexadecanedioate. {ECO:0000269|PubMed:19959665}.
Function Catalyzes the omega-hydroxylation of various fatty acids (FA). Acts on saturated and unsaturated fatty acids with chain lengths from C12 to C18. Involved in the biosynthesis of 16- hydroxypalmitate. {ECO:0000269|PubMed:15709153, ECO:0000269|PubMed:17427946, ECO:0000269|PubMed:19959665}.
Induction By abscisic acid (ABA), auxin, the etylene precursor ACC and cold treatment. Down-regulated by wounding and in etiolated seedlings. {ECO:0000269|PubMed:15709153}.
Similarity Belongs to the cytochrome P450 family. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed in stems, flowers and siliques. {ECO:0000269|PubMed:15709153}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010082 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15223436 RefSeq NP_171666 554 cytochrome P450, family 86, subfamily A, polypeptide 4

Identical Sequences to LMP010082 proteins

Reference Database Accession Length Protein Name
GI:15223436 EMBL CBD07662.1 554 unnamed protein product [Arabidopsis thaliana]
GI:15223436 EMBL CBD09676.1 554 unnamed protein product [Arabidopsis thaliana]
GI:15223436 EMBL CBD14334.1 554 unnamed protein product [Arabidopsis thaliana]
GI:15223436 EMBL CBD10336.1 554 unnamed protein product [Arabidopsis thaliana]
GI:15223436 EMBL CBC98101.1 554 unnamed protein product [Arabidopsis thaliana]
GI:15223436 GenBank AEE27310.1 554 cytochrome P450, family 86, subfamily A, polypeptide 4 [Arabidopsis thaliana]

Related Sequences to LMP010082 proteins

Reference Database Accession Length Protein Name
GI:15223436 EMBL CAW46434.1 554 unnamed protein product [Arabidopsis thaliana]
GI:15223436 EMBL CAW62763.1 554 unnamed protein product [Arabidopsis thaliana]
GI:15223436 EMBL CAW40956.1 554 unnamed protein product [Arabidopsis thaliana]
GI:15223436 EMBL CAW36028.1 554 unnamed protein product [Arabidopsis thaliana]
GI:15223436 EMBL CAW55752.1 554 unnamed protein product [Arabidopsis thaliana]
GI:15223436 EMBL CAW38867.1 554 unnamed protein product [Arabidopsis thaliana]