Gene/Proteome Database (LMPD)

LMPD ID
LMP010136
Gene ID
824315
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
diacylglycerol O-acyltransferase 2
Gene Symbol
AT3G51520
Alternate Names
diacylglycerol O-acyltransferase 2
Chromosome
3
EC Number
2.3.1.20

Proteins

diacylglycerol O-acyltransferase 2
Refseq ID NP_566952
Protein GI 18409359
UniProt ID Q9ASU1
mRNA ID NM_115011
Length 314
RefSeq Status REVIEWED
MGGSREFRAEEHSNQFHSIIAMAIWLGAIHFNVALVLCSLIFLPPSLSLMVLGLLSLFIFIPIDHRSKYGRKLARYICKHACNYFPVSLYVEDYEAFQPNRAYVFGYEPHSVLPIGVVALCDLTGFMPIPNIKVLASSAIFYTPFLRHIWTWLGLTAASRKNFTSLLDSGYSCVLVPGGVQETFHMQHDAENVFLSRRRGFVRIAMEQGSPLVPVFCFGQARVYKWWKPDCDLYLKLSRAIRFTPICFWGVFGSPLPCRQPMHVVVGKPIEVTKTLKPTDEEIAKFHGQYVEALRDLFERHKSRVGYDLELKIL

Gene Information

Entrez Gene ID
824315
Gene Name
diacylglycerol O-acyltransferase 2
Gene Symbol
AT3G51520
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IEA:UniProtKB-KW C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0004144 IDA:TAIR F diacylglycerol O-acyltransferase activity
GO:0006071 IEA:UniProtKB-KW P glycerol metabolic process
GO:0019432 IDA:TAIR P triglyceride biosynthetic process

BIOCYC Pathway Links

BIOCYC Pathway ID Description
TRIGLSYN-PWY triacylglycerol biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
6254309 Acyl chain remodeling of DAG and TAG
6253801 Glycerophospholipid biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR007130 Diacylglycerol acyltransferase

UniProt Annotations

Entry Information

Gene Name
diacylglycerol O-acyltransferase 2
Protein Entry
DGAT2_ARATH
UniProt ID
Q9ASU1
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity Acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.
Disruption Phenotype No decrease in oil content. {ECO:0000269|PubMed:20040537}.
Function Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for storage lipid synthesis (By similarity). {ECO:0000250}.
Pathway Glycerolipid metabolism; triacylglycerol biosynthesis.
Sequence Caution Sequence=CAB63016.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the diacylglycerol acyltransferase family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Ubiquitous. Lower levels in seeds than in other tissues. {ECO:0000269|PubMed:20101470}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010136 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
18409359 RefSeq NP_566952 314 diacylglycerol O-acyltransferase 2

Identical Sequences to LMP010136 proteins

Reference Database Accession Length Protein Name
GI:18409359 GenBank ABL51164.1 314 Sequence 96 from patent US 7135617
GI:18409359 GenBank ADR90375.1 314 Sequence 96 from patent US 7741532
GI:18409359 GenBank ADT60560.1 314 Sequence 2010 from patent US 7847156
GI:18409359 GenBank AEE78802.1 314 diacylglycerol O-acyltransferase 2 [Arabidopsis thaliana]
GI:18409359 GenBank AFA83934.1 314 Sequence 60 from patent US 8101818
GI:18409359 GenBank AGN69108.1 314 Sequence 15 from patent US 8431772

Related Sequences to LMP010136 proteins

Reference Database Accession Length Protein Name
GI:18409359 EMBL CAB63016.1 327 putative protein [Arabidopsis thaliana]
GI:18409359 GenBank ABL51170.1 314 Sequence 125 from patent US 7135617
GI:18409359 GenBank ACJ97004.1 314 Sequence 32 from patent US 7417176
GI:18409359 GenBank ADR90381.1 314 Sequence 125 from patent US 7741532
GI:18409359 GenBank AEF63660.1 314 Sequence 32 from patent US 7935863
GI:18409359 GenBank AEF76539.1 314 Sequence 32 from patent US 7939714