Gene/Proteome Database (LMPD)

LMPD ID
LMP010155
Gene ID
836801
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit
Gene Symbol
DGL1
Synonyms
DEFECTIVE GLYCOSYLATION; DGL1; MSN2.7; MSN2_7
Alternate Names
dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit
Chromosome
5
EC Number
2.4.99.18

Proteins

dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit
Refseq ID NP_569038
Protein GI 18425101
UniProt ID Q944K2
mRNA ID NM_126066
Length 437
RefSeq Status REVIEWED
MVNLSRSVALISVFLLPLLSFSFSVDNPTDRRVLVLLDDLSLKSSHSIFFNTLKSRGFDLDFKLAEDSKLALQRYGQYLYDGLIIFAPSTERFGGSLDSKSIADFVDSGRDLILSADTAASDLIRGIATECGVDFDEDSSAMVIDHTSFSVSDVDGDHTLIAADDLVKSDVILGKTKIEAPVLFRGVAHSLNPTNNLVLKVLSASPSAYSANPSSKLSSPPQLTGSSISLVSVMQARNNARVVISGSVQLFSDRLIRSGVQKAGSPNQYEKSGNEQFVTELSKWVFHERGHLKAGNLVHHRVGETDEPAIYRIKDDLEFSVEIYEWSGKSWEPYVANDVQVQFYMMSPYVLKTLSTDKKGLFHTSFKVPDVYGVFQFKVEYEKLGYTTLSLSKQIPVRPYRHNEYERFIPTAYPYYGACFTTMAGFFVFSFVYLYHK

Gene Information

Entrez Gene ID
836801
Gene Name
dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit
Gene Symbol
DGL1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IDA:TAIR C endoplasmic reticulum
GO:0005794 IDA:TAIR C Golgi apparatus
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016020 IDA:TAIR C membrane
GO:0005730 IDA:TAIR C nucleolus
GO:0008250 ISS:TAIR C oligosaccharyltransferase complex
GO:0009505 IDA:TAIR C plant-type cell wall
GO:0009506 IDA:TAIR C plasmodesma
GO:0005774 IDA:TAIR C vacuolar membrane
GO:0005773 IDA:TAIR C vacuole
GO:0004579 IEA:InterPro F dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0009664 IMP:TAIR P plant-type cell wall organization
GO:0018279 IMP:TAIR P protein N-linked glycosylation via asparagine
GO:0009826 IMP:TAIR P unidimensional cell growth

KEGG Pathway Links

KEGG Pathway ID Description
ath00510 N-Glycan biosynthesis
ath_M00072 N-glycosylation by oligosaccharyltransferase
ath04141 Protein processing in endoplasmic reticulum

REACTOME Pathway Links

REACTOME Pathway ID Description
6254345 SRP-dependent cotranslational protein targeting to membrane

Domain Information

InterPro Annotations

Accession Description
IPR005013 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1

UniProt Annotations

Entry Information

Gene Name
dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit
Protein Entry
OST48_ARATH
UniProt ID
Q944K2
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity Dolichyl diphosphooligosaccharide + [protein]- L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine.
Disruption Phenotype Embryo-lethal. {ECO:0000269|PubMed:15860005}.
Function Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. {ECO:0000269|PubMed:15860005}.
Pathway Protein modification; protein glycosylation.
Sequence Caution Sequence=BAA97274.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the DDOST 48 kDa subunit family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Subunit Component of the oligosaccharyltransferase (OST) complex. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010155 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
18425101 RefSeq NP_569038 437 dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit

Identical Sequences to LMP010155 proteins

Reference Database Accession Length Protein Name
GI:18425101 GenBank AAL16268.1 437 AT5g66680/MSN2_7 [Arabidopsis thaliana]
GI:18425101 GenBank AAN12926.1 437 putative dolichyl-di-phosphooligosaccharide glycotransferase (oligosaccharyltransferase) [Arabidopsis thaliana]
GI:18425101 gnl TAIR 437 dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit [Arabidopsis thaliana]
GI:18425101 SwissProt Q944K2.1 437 RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Short=Oligosaccharyl transferase 48 kDa subunit; AltName: Full=Protein DEFECTIVE GLYCOSYLATION 1; Flags: Precursor [Arabidopsis thaliana]

Related Sequences to LMP010155 proteins

Reference Database Accession Length Protein Name
GI:18425101 DBBJ BAA97274.1 442 dolichyl-di-phosphooligosaccharide-protein glycotransferase (oligosaccharyltransferase)-like [Arabidopsis thaliana]
GI:18425101 GenBank AAK59450.1 437 putative dolichyl-di-phosphooligosaccharide-protein glycotransferase [Arabidopsis thaliana]
GI:18425101 GenBank AAM63023.1 437 dolichyl-di-phosphooligosaccharide-protein glycotransferase (oligosaccharyltransferase)-like [Arabidopsis thaliana]
GI:18425101 GenBank EFH41311.1 437 hypothetical protein ARALYDRAFT_920056 [Arabidopsis lyrata subsp. lyrata]
GI:18425101 RefSeq XP_002865052.1 437 hypothetical protein ARALYDRAFT_920056 [Arabidopsis lyrata subsp. lyrata]
GI:18425101 RefSeq XP_006282122.1 437 hypothetical protein CARUB_v10028371mg [Capsella rubella]