Gene/Proteome Database (LMPD)

LMPD ID
LMP010158
Gene ID
840113
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
Gene Symbol
ATDAD1
Synonyms
DEFENDER AGAINST APOPTOTIC DEATH 1; F3C3.14; F3C3_14
Alternate Names
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
Chromosome
1
EC Number
2.4.99.18
Summary
Encodes protein involved in suppression of apoptosis. Complements a mammalian apoptosis suppressor mutation.
Orthologs
View orthologs and multiple alignments for ATDAD1

Proteins

dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
Refseq ID NP_174500
Protein GI 15222602
UniProt ID Q39080
mRNA ID NM_102954
Length 115
RefSeq Status REVIEWED
MVKSTSKDAQDLFRSLRSAYSATPTNLKIIDLYVVFAVFTALIQVVYMALVGSFPFNSFLSGVLSCIGTAVLAVCLRIQVNKENKEFKDLAPERAFADFVLCNLVLHLVIINFLG

Gene Information

Entrez Gene ID
840113
Gene Name
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
Gene Symbol
ATDAD1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IDA:TAIR C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016020 ISS:TAIR C membrane
GO:0008250 IEA:InterPro C oligosaccharyltransferase complex
GO:0004579 IEA:InterPro F dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0006915 IEA:UniProtKB-KW P apoptotic process
GO:0043069 IGI:TAIR P negative regulation of programmed cell death
GO:0006486 IEA:UniProtKB-UniPathway P protein glycosylation

KEGG Pathway Links

KEGG Pathway ID Description
ath00510 N-Glycan biosynthesis
ath04141 Protein processing in endoplasmic reticulum

Domain Information

InterPro Annotations

Accession Description
IPR003038 DAD/Ost2

UniProt Annotations

Entry Information

Gene Name
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
Protein Entry
DAD1_ARATH
UniProt ID
Q39080
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity Dolichyl diphosphooligosaccharide + [protein]- L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine.
Function Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Possesses cell death-inhibiting activity. {ECO:0000250}.
Pathway Protein modification; protein glycosylation.
Similarity Belongs to the DAD/OST2 family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Subunit Component of the oligosaccharyltransferase (OST) complex. {ECO:0000250}.
Tissue Specificity Ubiquitous.

Identical and Related Proteins

Unique RefSeq proteins for LMP010158 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15222602 RefSeq NP_174500 115 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

Identical Sequences to LMP010158 proteins

Reference Database Accession Length Protein Name
GI:15222602 EMBL CAC80054.1 115 DAD1 protein [Arabidopsis thaliana]
GI:15222602 GenBank ABD38892.1 115 At1g32210 [Arabidopsis thaliana]
GI:15222602 GenBank AEE31449.1 115 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 [Arabidopsis thaliana]
GI:15222602 GenBank AFX28689.1 115 Sequence 9749 from patent US 8299318
GI:15222602 GenBank AFX48621.1 115 Sequence 50454 from patent US 8299318
GI:15222602 SwissProt Q39080.2 115 RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Short=Oligosaccharyl transferase subunit DAD1; AltName: Full=Defender against cell death 1; Short=AtDAD1; Short=DAD-1 [Arabidopsis thaliana]

Related Sequences to LMP010158 proteins

Reference Database Accession Length Protein Name
GI:15222602 GenBank EFH69971.1 115 ATDAD1 [Arabidopsis lyrata subsp. lyrata]
GI:15222602 GenBank ESQ33591.1 115 hypothetical protein EUTSA_v10009144mg [Eutrema salsugineum]
GI:15222602 RefSeq XP_002893712.1 115 ATDAD1 [Arabidopsis lyrata subsp. lyrata]
GI:15222602 RefSeq XP_006415238.1 115 hypothetical protein EUTSA_v10009144mg [Eutrema salsugineum]
GI:15222602 RefSeq XP_010461039.1 115 PREDICTED: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 [Camelina sativa]
GI:15222602 RefSeq XP_010478643.1 115 PREDICTED: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 [Camelina sativa]