Gene/Proteome Database (LMPD)

LMPD ID
LMP010160
Gene ID
832089
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
Gene Symbol
STT3A
Synonyms
staurosporin and temperature sensitive 3-like A; STT3A; T29J13.110; T29J13_110
Alternate Names
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
Chromosome
5
EC Number
2.4.99.18

Proteins

dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
Refseq ID NP_568380
Protein GI 18419993
UniProt ID Q93ZY3
mRNA ID NM_121974
Length 779
RefSeq Status REVIEWED
MAALESPLPGTPTAMRNAFGNVLSVLILVLIGVLAFSIRLFSVIKYESVIHEFDPYFNYRVTQFLSKNGIYEFWNWFDDRTWYPLGRVIGGTVYPGLTLTAGTIWWGLNSLNIPLSVETVCVFTAPVFSAFASWATYLLTKEVKGSGAGLAAAALLAMVPSYISRSVAGSYDNEAVAIFALIFTFYLYIKTLNTGSLFYATLNALAYFYMVCSWGGYTFIINLIPMHVLLCIVTGRYSPRLYIAYAPLVVLGTLLAALVPVVGFNAVLTSEHFASFLVFIIIHVVALVYYIKGILSPKMFKVAVTLVVSIGMVVCFIVVAILVALVASSPTGGWSGRSLSLLDPTYASKYIPIIASVSEHQPPTWPSYFMDINVLAFLVPAGIIACFSPLSDASSFVVLYIVMSVYFSGVMVRLMLVLAPAACIMSGIALSQAFDVFTGSIKYQLGASSNSTDDAEDNTSTNNAPKDDVSAGKTDKGEEIVKERSSKKGKKKEREPADKPSVKAKIKKKALVLPLEASIVALLLLIMLGAFYVIHCVWAAAEAYSAPSIVLTSQSRDGLHVFDDFRESYAWLSHNTDVDDKVASWWDYGYQTTAMANRTVIVDNNTWNNTHIATVGTAMSSPEKAAWEIFNSLDVKYVLVVFGGLIGYPSDDINKFLWMVRIGGGVFPHIKEADYLRDGQYRIDSEATPTMLNSLMYKLSYYRFVETDGKGYDRVRRTEIGKKHFKLTHFEEVFTSHHWMVRLYKLKPPRNRIRGKAKKLKSKTSSGLSSKSAKKNPWV

Gene Information

Entrez Gene ID
832089
Gene Name
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
Gene Symbol
STT3A
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IDA:TAIR C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016020 IDA:TAIR C membrane
GO:0005886 IDA:TAIR C plasma membrane
GO:0004576 IEA:InterPro F oligosaccharyl transferase activity
GO:0006486 IEA:UniProtKB-UniPathway P protein glycosylation
GO:0047484 IMP:UniProtKB P regulation of response to osmotic stress
GO:0009651 IMP:TAIR P response to salt stress

KEGG Pathway Links

KEGG Pathway ID Description
ath00510 N-Glycan biosynthesis
ath_M00072 N-glycosylation by oligosaccharyltransferase
ath04141 Protein processing in endoplasmic reticulum
ko04141 Protein processing in endoplasmic reticulum

Domain Information

InterPro Annotations

Accession Description
IPR003674 Oligosaccharyl transferase, STT3 subunit

UniProt Annotations

Entry Information

Gene Name
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
Protein Entry
STT3A_ARATH
UniProt ID
Q93ZY3
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity Dolichyl diphosphooligosaccharide + [protein]- L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine.
Disruption Phenotype Salt/osmotic sensitivity associated with root tip growth arrest and swelling and the induction of lateral roots. {ECO:0000269|PubMed:12972670}.
Function Catalytic subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3A seems to be involved in complex substrate specificity (By similarity). Controls adaptive responses to salt/osmotic stress. Acts as a key glycosylation determinant for EFR function during plant innate immunity. {ECO:0000250, ECO:0000269|PubMed:12972670, ECO:0000269|PubMed:19763086, ECO:0000269|PubMed:19763087}.
Pathway Protein modification; protein glycosylation.
Similarity Belongs to the STT3 family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:16618929, ECO:0000269|PubMed:22923678}; Multi- pass membrane protein {ECO:0000269|PubMed:16618929, ECO:0000269|PubMed:22923678}.
Subunit Component of the oligosaccharyltransferase (OST) complex. {ECO:0000250}.
Tissue Specificity Expressed in the root and in the shoot. {ECO:0000269|PubMed:12972670}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010160 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
18419993 RefSeq NP_568380 779 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

Identical Sequences to LMP010160 proteins

Reference Database Accession Length Protein Name
GI:18419993 GenBank AAL07040.1 779 putative oligosaccharyl transferase STT3 [Arabidopsis thaliana]
GI:18419993 GenBank AHL38618.1 779 glycosyltransferase, partial [Arabidopsis thaliana]
GI:18419993 gnl TAIR 779 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A [Arabidopsis thaliana]
GI:18419993 SwissProt Q93ZY3.1 779 RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A; Short=Oligosaccharyl transferase subunit STT3A; Short=STT3-A; AltName: Full=Integral membrane protein 1; AltName: Full=Protein STAUROSPORIN AND TEMPERATURE SENSITIVE 3-LIKE A [Arabidopsis thaliana]

Related Sequences to LMP010160 proteins

Reference Database Accession Length Protein Name
GI:18419993 GenBank AAK91413.1 779 AT5g19690/T29J13_110 [Arabidopsis thaliana]
GI:18419993 GenBank AAL31142.1 779 AT5g19690/T29J13_110 [Arabidopsis thaliana]
GI:18419993 GenBank EFH48159.1 779 hypothetical protein ARALYDRAFT_488863 [Arabidopsis lyrata subsp. lyrata]
GI:18419993 GenBank EOA19998.1 776 hypothetical protein CARUB_v10000271mg [Capsella rubella]
GI:18419993 RefSeq XP_002871900.1 779 hypothetical protein ARALYDRAFT_488863 [Arabidopsis lyrata subsp. lyrata]
GI:18419993 RefSeq XP_006287100.1 776 hypothetical protein CARUB_v10000271mg [Capsella rubella]