Gene/Proteome Database (LMPD)

LMPD ID
LMP010219
Gene ID
820372
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
fatty acyl-CoA reductase 2
Gene Symbol
MS2
Synonyms
FAR2; FATTY ACID REDUCTASE 2; MALE STERILITY 2; MALE STERILITY PROTEIN 2; MEC18.1; MS2
Alternate Names
fatty acyl-CoA reductase 2
Chromosome
3
EC Number
1.2.1.n2
Summary
Similar to fatty acid reductases.
Orthologs
View orthologs and multiple alignments for MS2

Proteins

fatty acyl-CoA reductase 2
Refseq ID NP_187805
Protein GI 15229920
UniProt ID Q08891
mRNA ID NM_112032
Length 616
RefSeq Status REVIEWED
MEALFLSSSSSSIVASNKLTRLHNHCVWSTVIRDKKRFGPTWCRVGGGGDGGRNSNAERPIRVSSLLKDRGQVLIREQSSPAMDAETLVLSPNGNGRTIEINGVKTLMPFSGASMVGMKEGLGIISFLQGKKFLITGSTGFLAKVLIEKVLRMAPDVSKIYLLIKAKSKEAAIERLKNEVLDAELFNTLKETHGASYMSFMLTKLIPVTGNICDSNIGLQADSAEEIAKEVDVIINSAANTTFNERYDVALDINTRGPGNLMGFAKKCKKLKLFLQVSTAYVNGQRQGRIMEKPFSMGDCIATENFLEGNRKALDVDREMKLALEAARKGTQNQDEAQKMKDLGLERARSYGWQDTYVFTKAMGEMMINSTRGDVPVVIIRPSVIESTYKDPFPGWMEGNRMMDPIVLCYGKGQLTGFLVDPKGVLDVVPADMVVNATLAAIAKHGMAMSDPEPEINVYQIASSAINPLVFEDLAELLYNHYKTSPCMDSKGDPIMVRLMKLFNSVDDFSDHLWRDAQERSGLMSGMSSVDSKMMQKLKFICKKSVEQAKHLATIYEPYTFYGGRFDNSNTQRLMENMSEDEKREFGFDVGSINWTDYITNVHIPGLRRHVLKGRA

Gene Information

Entrez Gene ID
820372
Gene Name
fatty acyl-CoA reductase 2
Gene Symbol
MS2
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0080019 IDA:TAIR F fatty-acyl-CoA reductase (alcohol-forming) activity
GO:0016628 ISS:TAIR F oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
GO:0006629 IEA:UniProtKB-KW P lipid metabolic process
GO:0010584 IMP:TAIR P pollen exine formation

KEGG Pathway Links

KEGG Pathway ID Description
ath00073 Cutin, suberine and wax biosynthesis
ath04146 Peroxisome
ko04146 Peroxisome

REACTOME Pathway Links

REACTOME Pathway ID Description
6254165 Plasmalogen biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR026055 Fatty acyl-CoA reductase
IPR013120 Male sterility, NAD-binding
IPR016040 NAD(P)-binding domain

UniProt Annotations

Entry Information

Gene Name
fatty acyl-CoA reductase 2
Protein Entry
FACR2_ARATH
UniProt ID
Q08891
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity Hexadecanal + CoA + NADP(+) = hexadecanoyl-CoA + NADPH.
Developmental Stage Expressed during microsporogenesis when microspores are released from tetrads. {ECO:0000269|PubMed:9351246}.
Disruption Phenotype Male sterility. {ECO:0000269|PubMed:8390620, ECO:0000269|PubMed:9351246}.
Function Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. Involved in the synthesis of the lipid component in sporopollenin. {ECO:0000269|PubMed:19062129, ECO:0000269|PubMed:9351246}.
Similarity Belongs to the fatty acyl-CoA reductase family. {ECO:0000305}.
Tissue Specificity Expressed in tapetum. {ECO:0000269|PubMed:9351246}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010219 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15229920 RefSeq NP_187805 616 fatty acyl-CoA reductase 2

Identical Sequences to LMP010219 proteins

Reference Database Accession Length Protein Name
GI:15229920 DBBJ BAB03110.1 616 male sterility protein 2 [Arabidopsis thaliana]
GI:15229920 GenBank AAG51054.1 616 male sterility protein 2 (MS2); 67648-65205 [Arabidopsis thaliana]
GI:15229920 GenBank ABZ10952.1 616 fatty acyl CoA reductase [Arabidopsis thaliana]
GI:15229920 GenBank AEE75132.1 616 fatty acyl-CoA reductase 2 [Arabidopsis thaliana]
GI:15229920 SwissProt Q08891.2 616 RecName: Full=Fatty acyl-CoA reductase 2; AltName: Full=Fatty acid reductase 2; AltName: Full=Male sterility protein 2 [Arabidopsis thaliana]

Related Sequences to LMP010219 proteins

Reference Database Accession Length Protein Name
GI:15229920 EMBL CAA52019.1 616 male sterility 2 (MS2) protein [Arabidopsis thaliana]
GI:15229920 EMBL CAA02615.1 616 unnamed protein product [Arabidopsis thaliana]
GI:15229920 GenBank EFH59018.1 616 hypothetical protein ARALYDRAFT_478549 [Arabidopsis lyrata subsp. lyrata]
GI:15229920 PRF - 616 male sterility 2 gene [Arabidopsis thaliana]
GI:15229920 RefSeq XP_002882759.1 616 hypothetical protein ARALYDRAFT_478549 [Arabidopsis lyrata subsp. lyrata]
GI:15229920 RefSeq XP_010464946.1 616 PREDICTED: fatty acyl-CoA reductase 2-like [Camelina sativa]