Gene/Proteome Database (LMPD)

LMPD ID
LMP010236
Gene ID
814851
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
galactoside 2-alpha-L-fucosyltransferase
Gene Symbol
FT1
Synonyms
2)-FUCOSYLTRANSFERASE; A-(1; ARABIDOPSIS THALIANA FUCOSYLTRANSFERASE 1; ATFT1; ATFUT1; FT1; fucosyltransferase 1; MUR2; MURUS 2; T18E12.11; T18E12_11; XYLOGLUCAN FUCOSYLTRANSFERASE
Alternate Names
galactoside 2-alpha-L-fucosyltransferase
Chromosome
2
EC Number
2.4.1.69
Summary
member of Glycosyltransferase Family- 37
Orthologs
View orthologs and multiple alignments for FT1

Proteins

galactoside 2-alpha-L-fucosyltransferase
Refseq ID NP_178421
Protein GI 15227566
UniProt ID Q9SWH5
mRNA ID NM_126373
Length 558
RefSeq Status REVIEWED
MDQNSYRRRSSPIRTTTGGSKSVNFSELLQMKYLSSGTMKLTRTFTTCLIVFSVLVAFSMIFHQHPSDSNRIMGFAEARVLDAGVFPNVTNINSDKLLGGLLASGFDEDSCLSRYQSVHYRKPSPYKPSSYLISKLRNYEKLHKRCGPGTESYKKALKQLDQEHIDGDGECKYVVWISFSGLGNRILSLASVFLYALLTDRVLLVDRGKDMDDLFCEPFLGMSWLLPLDFPMTDQFDGLNQESSRCYGYMVKNQVIDTEGTLSHLYLHLVHDYGDHDKMFFCEGDQTFIGKVPWLIVKTDNYFVPSLWLIPGFDDELNKLFPQKATVFHHLGRYLFHPTNQVWGLVTRYYEAYLSHADEKIGIQVRVFDEDPGPFQHVMDQISSCTQKEKLLPEVDTLVERSRHVNTPKHKAVLVTSLNAGYAENLKSMYWEYPTSTGEIIGVHQPSQEGYQQTEKKMHNGKALAEMYLLSLTDNLVTSAWSTFGYVAQGLGGLKPWILYRPENRTTPDPSCGRAMSMEPCFHSPPFYDCKAKTGIDTGTLVPHVRHCEDISWGLKLV

Gene Information

Entrez Gene ID
814851
Gene Name
galactoside 2-alpha-L-fucosyltransferase
Gene Symbol
FT1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IDA:TAIR C Golgi apparatus
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0008417 ISS:TAIR F fucosyltransferase activity
GO:0008107 IEA:UniProtKB-EC F galactoside 2-alpha-L-fucosyltransferase activity
GO:0042546 IEA:InterPro P cell wall biogenesis
GO:0071555 IEA:UniProtKB-KW P cell wall organization
GO:0036065 ISS:GOC P fucosylation
GO:0006486 IEA:UniProtKB-UniPathway P protein glycosylation
GO:0009969 IDA:TAIR P xyloglucan biosynthetic process

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-5936 xyloglucan biosynthesis
PWY-5936 xyloglucan biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR004938 Xyloglucan fucosyltransferase

UniProt Annotations

Entry Information

Gene Name
galactoside 2-alpha-L-fucosyltransferase
Protein Entry
FUT1_ARATH
UniProt ID
Q9SWH5
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity GDP-beta-L-fucose + beta-D-galactosyl-(1->3)- N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta- D-glucosyl-(1<->1)-ceramide = GDP + alpha-L-fucosyl-(1->2)-beta-D- galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D- galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide.
Function Involved in cell wall biosynthesis. Is both necessary and sufficient for the addition of the terminal fucosyl residue on xyloglucan side chains, but is not involved in the fucosylation of other cell wall components. {ECO:0000269|PubMed:10373113, ECO:0000269|PubMed:11743104, ECO:0000269|PubMed:11854459, ECO:0000269|PubMed:14730072}.
Pathway Protein modification; protein glycosylation.
Similarity Belongs to the glycosyltransferase 37 family. {ECO:0000305}.
Subcellular Location Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:21143678}; Single-pass type II membrane protein {ECO:0000269|PubMed:21143678}. Note=Membrane-bound form in trans cisternae of Golgi.
Tissue Specificity Expressed in roots, stems, leaves, flowers, siliques and seedlings. {ECO:0000269|PubMed:11743104}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010236 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15227566 RefSeq NP_178421 558 galactoside 2-alpha-L-fucosyltransferase

Identical Sequences to LMP010236 proteins

Reference Database Accession Length Protein Name
GI:15227566 GenBank AAV16368.1 558 Sequence 1 from patent US 6747190
GI:15227566 GenBank ACX19716.1 558 Sequence 47994 from patent US 7569389
GI:15227566 GenBank AEC05676.1 558 galactoside 2-alpha-L-fucosyltransferase [Arabidopsis thaliana]
GI:15227566 GenBank AFX49652.1 558 Sequence 51485 from patent US 8299318
GI:15227566 GenBank AGF14604.1 558 Sequence 14023 from patent US 8362325
GI:15227566 GenBank AHL38862.1 558 glycosyltransferase, partial [Arabidopsis thaliana]

Related Sequences to LMP010236 proteins

Reference Database Accession Length Protein Name
GI:15227566 GenBank AAD41092.1 558 xyloglucan fucosyltransferase [Arabidopsis thaliana]
GI:15227566 GenBank EFH53130.1 561 hypothetical protein ARALYDRAFT_484227 [Arabidopsis lyrata subsp. lyrata]
GI:15227566 GenBank EOA23733.1 561 hypothetical protein CARUB_v10016945mg [Capsella rubella]
GI:15227566 RefSeq XP_002876871.1 561 hypothetical protein ARALYDRAFT_484227 [Arabidopsis lyrata subsp. lyrata]
GI:15227566 RefSeq XP_006290835.1 561 hypothetical protein CARUB_v10016945mg [Capsella rubella]
GI:15227566 RefSeq XP_010502330.1 561 PREDICTED: galactoside 2-alpha-L-fucosyltransferase [Camelina sativa]