Gene/Proteome Database (LMPD)

LMPD ID
LMP010355
Gene ID
841377
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
geranylgeranyl pyrophosphate synthase 6
Gene Symbol
GGPS6
Synonyms
F14J22.23; geranylgeranyl pyrophosphate synthase 6; GGPS6
Alternate Names
geranylgeranyl pyrophosphate synthase 6
Chromosome
1
EC Number
2.5.1.-
Summary
encodes a mitochondria-targeted geranylgeranyl pyrophosphate synthase
Orthologs
View orthologs and multiple alignments for GGPS6

Proteins

geranylgeranyl pyrophosphate synthase 6
Refseq ID NP_175376
Protein GI 15222767
UniProt ID O22043
mRNA ID NM_103841
Length 336
RefSeq Status REVIEWED
MRPRYSLILSAMRLIRPSNRRLSSIASSDSEFISYMKNKAKSINKALDNSIPLCNNFVPLWEPVLEVHKAMRYTLLPGGKRVRPMLCLVACELVGGQESTAMPAACAVEMIHAASLILDDLPCMDDDSLRRGKPTNHKVFGEKTSILASNALRSLAVKQTLASTSLGVTSERVLRAVQEMARAVGTEGLVAGQAADLAGERMSFKNEDDELRYLELMHVHKTAVLVEAAAVVGAIMGGGSDEEIERLKSYARCVGLMFQVMDDVLDETKSSEELGKTAGKDLITGKLTYPKVMGVDNAREYAKRLNREAQEHLQGFDSDKVVPLLSLADYIVKRQN

Gene Information

Entrez Gene ID
841377
Gene Name
geranylgeranyl pyrophosphate synthase 6
Gene Symbol
GGPS6
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IDA:TAIR C mitochondrion
GO:0004161 IEA:UniProtKB-EC F dimethylallyltranstransferase activity
GO:0004311 IDA:TAIR F farnesyltranstransferase activity
GO:0004337 IEA:UniProtKB-EC F geranyltranstransferase activity
GO:0046872 IEA:UniProtKB-KW F metal ion binding
GO:0016117 IEA:UniProtKB-KW P carotenoid biosynthetic process
GO:0045337 IEA:UniProtKB-UniPathway P farnesyl diphosphate biosynthetic process
GO:0033384 IEA:UniProtKB-UniPathway P geranyl diphosphate biosynthetic process
GO:0033386 IEA:UniProtKB-UniPathway P geranylgeranyl diphosphate biosynthetic process
GO:0008299 TAS:TAIR P isoprenoid biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath01110 Biosynthesis of secondary metabolites
ath01100 Metabolic pathways
ath00900 Terpenoid backbone biosynthesis
ko00900 Terpenoid backbone biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR008949 Isoprenoid synthase domain
IPR000092 Polyprenyl synthetase
IPR017446 Polyprenyl synthetase-related

UniProt Annotations

Entry Information

Gene Name
geranylgeranyl pyrophosphate synthase 6
Protein Entry
GGPP6_ARATH
UniProt ID
O22043
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.
Catalytic Activity Dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.
Catalytic Activity Geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2E,6E)-farnesyl diphosphate.
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Binds 3 Mg(2+) ions per subunit. {ECO:0000250};
Function Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate.
Pathway Isoprenoid biosynthesis; farnesyl diphosphate biosynthesis; farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1.
Pathway Isoprenoid biosynthesis; geranyl diphosphate biosynthesis; geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1.
Pathway Isoprenoid biosynthesis; geranylgeranyl diphosphate biosynthesis; geranylgeranyl diphosphate from farnesyl diphosphate and isopentenyl diphosphate: step 1/1.
Similarity Belongs to the FPP/GGPP synthase family. {ECO:0000305}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:10759500, ECO:0000269|PubMed:9349257}.
Subunit Monomer. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010355 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15222767 RefSeq NP_175376 336 geranylgeranyl pyrophosphate synthase 6

Identical Sequences to LMP010355 proteins

Reference Database Accession Length Protein Name
GI:15222767 GenBank AAD43148.1 336 geranyl geranyl pyrophosphate synthase [Arabidopsis thaliana]
GI:15222767 GenBank AAR92266.1 336 At1g49530 [Arabidopsis thaliana]
GI:15222767 GenBank AAS76253.1 336 At1g49530 [Arabidopsis thaliana]
GI:15222767 GenBank AEE32439.1 336 geranylgeranyl pyrophosphate synthase 6 [Arabidopsis thaliana]
GI:15222767 SwissProt O22043.2 336 RecName: Full=Geranylgeranyl pyrophosphate synthase 6, mitochondrial; Short=GGPP synthase 6; Short=GGPS6; AltName: Full=(2E,6E)-farnesyl diphosphate synthase 6; AltName: Full=Dimethylallyltranstransferase 6; AltName: Full=Farnesyl diphosphate synthase 6; AltName: Full=Farnesyltranstransferase 6; AltName: Full=Geranyltranstransferase 6; Flags: Precursor [Arabidopsis thaliana]

Related Sequences to LMP010355 proteins

Reference Database Accession Length Protein Name
GI:15222767 DBBJ BAA23157.1 343 geranyl geranyl pyrophosphate synthase [Arabidopsis thaliana]
GI:15222767 EMBL CBF64673.1 343 unnamed protein product [Arabidopsis thaliana]
GI:15222767 EMBL CBU89549.1 343 unnamed protein product [Arabidopsis thaliana]
GI:15222767 GenBank EFH67775.1 337 hypothetical protein ARALYDRAFT_891852 [Arabidopsis lyrata subsp. lyrata]
GI:15222767 GenBank AGX56551.1 343 Sequence 13440 from patent US 8541208
GI:15222767 RefSeq XP_002891516.1 337 hypothetical protein ARALYDRAFT_891852 [Arabidopsis lyrata subsp. lyrata]