Gene/Proteome Database (LMPD)

LMPD ID
LMP010412
Gene ID
818389
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
bifunctional sn-glycerol-3-phosphate 2-O-acyltransferase/phosphatase
Gene Symbol
GPAT6
Synonyms
ATGPAT6; F16M14.4; F16M14_4; glycerol-3-phosphate acyltransferase 6; GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 6; GPAT6
Alternate Names
bifunctional sn-glycerol-3-phosphate 2-O-acyltransferase/phosphatase
Chromosome
2
EC Number
2.3.1.198
Summary
Encodes a protein with glycerol-3-phosphate acyltransferase activity.
Orthologs
View orthologs and multiple alignments for GPAT6

Proteins

bifunctional sn-glycerol-3-phosphate 2-O-acyltransferase/phosphatase
Refseq ID NP_181346
Protein GI 15224445
UniProt ID O80437
mRNA ID NM_129367
Length 501
RefSeq Status REVIEWED
MGAQEKRRRFEQISKCDVKDRSNHTVAADLDGTLLISRSAFPYYFLVALEAGSLLRALILLVSVPFVYLTYLTISETLAINVFVFITFAGLKIRDVELVVRSVLPRFYAEDVRPDTWRIFNTFGKRYIITASPRIMVEPFVKTFLGVDKVLGTELEVSKSGRATGFTRKPGILVGQYKRDVVLREFGGLASDLPDLGLGDSKTDHDFMSICKEGYMVPRTKCEPLPRNKLLSPIIFHEGRLVQRPTPLVALLTFLWLPVGFVLSIIRVYTNIPLPERIARYNYKLTGIKLVVNGHPPPPPKPGQPGHLLVCNHRTVLDPVVTAVALGRKISCVTYSISKFSELISPIKAVALTRQREKDAANIKRLLEEGDLVICPEGTTCREPFLLRFSALFAELTDRIVPVAINTKQSMFNGTTTRGYKLLDPYFAFMNPRPTYEITFLKQIPAELTCKGGKSPIEVANYIQRVLGGTLGFECTNFTRKDKYAMLAGTDGRVPVKKEKT

Gene Information

Entrez Gene ID
818389
Gene Name
bifunctional sn-glycerol-3-phosphate 2-O-acyltransferase/phosphatase
Gene Symbol
GPAT6
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0090447 IDA:TAIR F glycerol-3-phosphate 2-O-acyltransferase activity
GO:0016791 IDA:TAIR F phosphatase activity
GO:0010143 IMP:TAIR P cutin biosynthetic process
GO:0016311 IDA:GOC P dephosphorylation
GO:0009908 IMP:TAIR P flower development
GO:0008654 IEA:UniProtKB-KW P phospholipid biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath00561 Glycerolipid metabolism
ath00564 Glycerophospholipid metabolism
ko00564 Glycerophospholipid metabolism
ath01100 Metabolic pathways

Domain Information

InterPro Annotations

Accession Description
IPR023214 HAD-like domain
IPR002123 Phospholipid/glycerol acyltransferase

UniProt Annotations

Entry Information

Gene Name
bifunctional sn-glycerol-3-phosphate 2-O-acyltransferase/phosphatase
Protein Entry
GPAT6_ARATH
UniProt ID
O80437
Species
Arabidopsis

Comments

Comment Type Description
Biophysicochemical Properties Kinetic parameters: Vmax=278.56 pmol/min/mg enzyme {ECO:0000269|PubMed:12897259};
Catalytic Activity An acyl-CoA + sn-glycerol 3-phosphate = CoA + a 2-acyl-sn-glycerol 3-phosphate. {ECO:0000269|PubMed:12897259, ECO:0000269|PubMed:20551224}.
Domain The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. {ECO:0000250}.
Function Esterifies acyl-group from acyl-ACP to the sn-2 position of glycerol-3-phosphate, a step in cutin biosynthesis. {ECO:0000269|PubMed:20551224}.
Similarity Belongs to the GPAT/DAPAT family. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Specifically expressed in flower buds. {ECO:0000269|PubMed:12897259}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010412 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15224445 RefSeq NP_181346 501 bifunctional sn-glycerol-3-phosphate 2-O-acyltransferase/phosphatase

Identical Sequences to LMP010412 proteins

Reference Database Accession Length Protein Name
GI:15224445 GenBank AAL32799.1 501 Unknown protein [Arabidopsis thaliana]
GI:15224445 GenBank AAM47976.1 501 unknown protein [Arabidopsis thaliana]
GI:15224445 GenBank ACX19719.1 501 Sequence 47998 from patent US 7569389
GI:15224445 GenBank AEC09490.1 501 bifunctional sn-glycerol-3-phosphate 2-O-acyltransferase/phosphatase [Arabidopsis thaliana]
GI:15224445 gnl TIGR 501 unknown protein [Arabidopsis thaliana]
GI:15224445 SwissProt O80437.1 501 RecName: Full=Glycerol-3-phosphate 2-O-acyltransferase 6; Short=AtGPAT6; AltName: Full=Glycerol-3-phosphate acyltransferase 6 [Arabidopsis thaliana]

Related Sequences to LMP010412 proteins

Reference Database Accession Length Protein Name
GI:15224445 GenBank EFH57823.1 501 glycerol-3-phosphate acyltransferase 6 [Arabidopsis lyrata subsp. lyrata]
GI:15224445 GenBank EOA26964.1 502 hypothetical protein CARUB_v10023060mg [Capsella rubella]
GI:15224445 RefSeq XP_002881564.1 501 glycerol-3-phosphate acyltransferase 6 [Arabidopsis lyrata subsp. lyrata]
GI:15224445 RefSeq XP_010505423.1 502 PREDICTED: glycerol-3-phosphate 2-O-acyltransferase 6 [Camelina sativa]
GI:15224445 RefSeq XP_010509226.1 502 PREDICTED: glycerol-3-phosphate 2-O-acyltransferase 6-like [Camelina sativa]
GI:15224445 RefSeq XP_010517096.1 502 PREDICTED: glycerol-3-phosphate 2-O-acyltransferase 6-like [Camelina sativa]