Gene/Proteome Database (LMPD)

LMPD ID
LMP010441
Gene ID
835805
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
glycylpeptide N-tetradecanoyltransferase 1
Gene Symbol
NMT1
Synonyms
ARABIDOPSIS THALIANA MYRISTOYL-COA:PROTEIN N-MYRISTOYLTRANSFERASE; ATNMT1; MHM17.15; MHM17_15; myristoyl-CoA:protein N-myristoyltransferase; N-MYRISTOYLTRANSFERASE 1; NMT1
Alternate Names
glycylpeptide N-tetradecanoyltransferase 1
Chromosome
5
EC Number
2.3.1.97

Proteins

glycylpeptide N-tetradecanoyltransferase 1
Refseq ID NP_568846
Protein GI 18423927
UniProt ID Q9LTR9
mRNA ID NM_125084
Length 434
RefSeq Status REVIEWED
MADNNSPPGSVEQKADQIVEANPLVKDDTSLETIVRRFQDSMSEAKTHKFWETQPVGQFKDIGDTSLPEGPIEPATPLSEVKQEPYNLPSVYEWTTCDMNSDDMCSEVYNLLKNNYVEDDENMFRFNYSKEFLRWALRPPGYYQSWHIGVRAKTSKKLVAFISGVPARIRVRDEVVKMAEINFLCVHKKLRSKRLAPVMIKEVTRRVHLENIWQAAYTAGVILPTPITTCQYWHRSLNPKKLIDVGFSRLGARMTMSRTIKLYKLPDAPITPGFRKMEPRDVPAVTRLLRNYLSQFGVATDFDENDVEHWLLPREDVVDSYLVESPETHDVTDFCSFYTLPSTILGNPNYTTLKAAYSYYNVATQTSFLQLMNDALIVSKQKGFDVFNALDVMHNESFLKELKFGPGDGQLHYYLYNYRLKSALKPAELGLVLL

Gene Information

Entrez Gene ID
835805
Gene Name
glycylpeptide N-tetradecanoyltransferase 1
Gene Symbol
NMT1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 IDA:TAIR C cytosol
GO:0005840 IDA:TAIR C ribosome
GO:0004379 IDA:TAIR F glycylpeptide N-tetradecanoyltransferase activity
GO:0019107 IDA:TAIR F myristoyltransferase activity
GO:0006499 IDA:TAIR P N-terminal protein myristoylation
GO:0010064 IMP:TAIR P embryonic shoot morphogenesis
GO:0040007 IMP:TAIR P growth

Domain Information

InterPro Annotations

Accession Description
IPR016181 Acyl-CoA N-acyltransferase
IPR000903 Myristoyl-CoA:protein N-myristoyltransferase
IPR022677 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal
IPR022676 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal
IPR022678 Myristoyl-CoA:protein N-myristoyltransferase, conserved site

UniProt Annotations

Entry Information

Gene Name
glycylpeptide N-tetradecanoyltransferase 1
Protein Entry
NMT1_ARATH
UniProt ID
Q9LTR9
Species
Arabidopsis

Comments

Comment Type Description
Biophysicochemical Properties Kinetic parameters: KM=3.7 uM for myristoyl-CoA, in the presence of CPK3 {ECO:0000269|PubMed:10734119}; pH dependence: Optimum pH is 7.8. Active from pH 5.5 to 8.5. {ECO:0000269|PubMed:10734119};
Catalytic Activity Tetradecanoyl-CoA + glycylpeptide = CoA + N- tetradecanoylglycylpeptide.
Function Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins. Can also use decanoyl-CoA and lauroyl-CoA as substrates. {ECO:0000269|PubMed:10734119, ECO:0000269|PubMed:12912986}.
Sequence Caution Sequence=BAA97032.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the NMT family. {ECO:0000305}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10734119}. Note=Mostly associated to ribosomes. Present to a lower extent in mitochondria.
Tissue Specificity Expressed ubiquitously, with higher levels in young tissues (at protein level). {ECO:0000269|PubMed:10734119}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010441 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
18423927 RefSeq NP_568846 434 glycylpeptide N-tetradecanoyltransferase 1

Identical Sequences to LMP010441 proteins

Reference Database Accession Length Protein Name
GI:18423927 GenBank AAK76528.1 434 putative N-myristoyl transferase [Arabidopsis thaliana]
GI:18423927 GenBank AAM14319.1 434 putative N-myristoyl transferase [Arabidopsis thaliana]
GI:18423927 GenBank AAM65089.1 434 N-myristoyl transferase [Arabidopsis thaliana]
GI:18423927 GenBank ADT60132.1 434 Sequence 1154 from patent US 7847156
GI:18423927 gnl TAIR 434 glycylpeptide N-tetradecanoyltransferase 1 [Arabidopsis thaliana]
GI:18423927 SwissProt Q9LTR9.2 434 RecName: Full=Glycylpeptide N-tetradecanoyltransferase 1; AltName: Full=Myristoyl-CoA:protein N-myristoyltransferase 1; Short=NMT 1; Short=Type I N-myristoyltransferase 1; AltName: Full=Peptide N-myristoyltransferase 1 [Arabidopsis thaliana]

Related Sequences to LMP010441 proteins

Reference Database Accession Length Protein Name
GI:18423927 GenBank EFH40751.1 434 N-myristoyltransferase 1 [Arabidopsis lyrata subsp. lyrata]
GI:18423927 GenBank EOA13389.1 434 hypothetical protein CARUB_v10026431mg [Capsella rubella]
GI:18423927 RefSeq XP_002864492.1 434 N-myristoyltransferase 1 [Arabidopsis lyrata subsp. lyrata]
GI:18423927 RefSeq XP_006280491.1 434 hypothetical protein CARUB_v10026431mg [Capsella rubella]
GI:18423927 RefSeq XP_010451734.1 434 PREDICTED: glycylpeptide N-tetradecanoyltransferase 1 [Camelina sativa]
GI:18423927 RefSeq XP_010443367.1 434 PREDICTED: glycylpeptide N-tetradecanoyltransferase 1-like [Camelina sativa]