Gene/Proteome Database (LMPD)

LMPD ID
LMP010498
Gene ID
841841
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
protein MODIFIED VACUOLE PHENOTYPE 1
Gene Symbol
MVP1
Synonyms
F15I1.11; F15I1_11; MODIFIED VACUOLE PHENOTYPE 1; MVP1
Alternate Names
protein MODIFIED VACUOLE PHENOTYPE 1
Chromosome
1

Proteins

protein MODIFIED VACUOLE PHENOTYPE 1
Refseq ID NP_175805
Protein GI 15221023
UniProt ID Q7XA74
mRNA ID NM_104280
Length 417
RefSeq Status REVIEWED
MLLIPSFTANSNEPPPSKLSLSDLSMAILKSHFFLLFPLLLLHFHTVSFAQTLFVFGDGLYDAGNKQFLSQNRVDASFPPYGVTVGQATGRWSDGSIVPDYLAKFMGIPKISPILLTTADFSHGANFAIADATVLGSPPETMTLSQQVKKFSENKNKWTNQTRSEAIYLIYIGSDDYLSYAKSNPSPSDTQKQAFVDQVITTIKAEIKVVYGSGGRKFAFQNLAPLGCLPAVKQASGNVQECVKLPSEMAALHNKKLLQLLVELSRELNGFQYSFYDFFSSIQNRVIKSKTYTFETGNAACCGTGSINGSNCSAKNVCAKPEEYIFFDGKHLTQEANLQVGHLMWGADPEVIGPNNIRELMVLPLDITVILAGIQEAMAAMRPRQSNIESLYDIKKMESEMDNHWLYQVDKAISFMI

Gene Information

Entrez Gene ID
841841
Gene Name
protein MODIFIED VACUOLE PHENOTYPE 1
Gene Symbol
MVP1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0010168 IDA:TAIR C ER body
GO:0005783 IDA:TAIR C endoplasmic reticulum
GO:0009705 IDA:TAIR C plant-type vacuole membrane
GO:0009506 IDA:TAIR C plasmodesma
GO:0005773 IDA:TAIR C vacuole
GO:0016788 IEA:InterPro F hydrolase activity, acting on ester bonds
GO:0007029 IMP:TAIR P endoplasmic reticulum organization
GO:0006886 IMP:TAIR P intracellular protein transport
GO:0006629 IEA:InterPro P lipid metabolic process
GO:0032527 IMP:TAIR P protein exit from endoplasmic reticulum

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-6303 methyl indole-3-acetate interconversion

Domain Information

InterPro Annotations

Accession Description
IPR001087 Lipase, GDSL

UniProt Annotations

Entry Information

Gene Name
protein MODIFIED VACUOLE PHENOTYPE 1
Protein Entry
GDL21_ARATH
UniProt ID
Q7XA74
Species
Arabidopsis

Comments

Comment Type Description
Caution Lacks the conserved active site 'GDSL' motif and has no lipase activity. {ECO:0000305}.
Developmental Stage Expressed during all developmental stages, with the highest accumulation in germinated seeds. {ECO:0000269|PubMed:19880612}.
Disruption Phenotype Defects in endoplasmic reticulum (ER) protein export and organizational defects in the ER, including aggregation of ER around the nucleus. Increased sensitivity to salt. {ECO:0000269|PubMed:19880612, ECO:0000269|PubMed:20626647, ECO:0000269|PubMed:23155454}.
Function Involved in organization of the endomembrane system and is required for endoplasmic reticulum morphology and organelle distribution. May act by inhibiting the formation of PYK10 complex by binding to GLL23 and exporting it from the ER. Required for proper subcellular localization of myrosinase TGG2. Has no lipase or esterase activity. {ECO:0000269|PubMed:19880612, ECO:0000269|PubMed:20626647, ECO:0000269|PubMed:23155454, ECO:0000269|PubMed:24330158}.
Induction Up-regualted by methyl jasmonate and upon pathogen infection. {ECO:0000269|PubMed:19880612}.
Sequence Caution Sequence=AAD25775.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAM65534.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAM65534.1; Type=Miscellaneous discrepancy; Note=The stop codon at position 16 is created by sequencing errors.; Evidence={ECO:0000305};
Similarity Belongs to the 'GDSL' lipolytic enzyme family. {ECO:0000305}.
Subcellular Location Vacuole. Endoplasmic reticulum. Note=Also found in ER bodies. Retained in the ER when mutated.
Subunit Interacts with the PYK10 complex and TGG2, but not with TGG1 or PEN2. {ECO:0000269|PubMed:19880612, ECO:0000269|PubMed:23155454}.
Tissue Specificity Expressed throughout the seedling, rosette leaves, roots, inflorescence and imbibed seed, but not in pollen. {ECO:0000269|PubMed:19880612}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010498 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15221023 RefSeq NP_175805 417 protein MODIFIED VACUOLE PHENOTYPE 1

Identical Sequences to LMP010498 proteins

Reference Database Accession Length Protein Name
GI:15221023 EMBL CBC39266.1 417 unnamed protein product [Arabidopsis thaliana]
GI:15221023 EMBL CBC10249.1 417 unnamed protein product [Arabidopsis thaliana]
GI:15221023 EMBL CBC89562.1 417 unnamed protein product [Arabidopsis thaliana]
GI:15221023 EMBL CBC58431.1 417 unnamed protein product [Arabidopsis thaliana]
GI:15221023 GenBank ADT60397.1 417 Sequence 1684 from patent US 7847156
GI:15221023 GenBank AEE33038.1 417 GDSL esterase/lipase [Arabidopsis thaliana]

Related Sequences to LMP010498 proteins

Reference Database Accession Length Protein Name
GI:15221023 EMBL CAW53839.1 430 unnamed protein product [Arabidopsis thaliana]
GI:15221023 EMBL CAW70236.1 430 unnamed protein product [Arabidopsis thaliana]
GI:15221023 EMBL CAW60624.1 430 unnamed protein product [Arabidopsis thaliana]
GI:15221023 EMBL CAW45025.1 430 unnamed protein product [Arabidopsis thaliana]
GI:15221023 EMBL CAW87439.1 430 unnamed protein product [Arabidopsis thaliana]
GI:15221023 GenBank AAD25775.1 430 Belongs to the PF|00657 Lipase/Acylhydrolase with GDSL-motif family. ESTs gb|T75865, gb|R30449, gb|AI239373, gb|F19931 and gb|F19930 come from this gene [Arabidopsis thaliana]