Gene/Proteome Database (LMPD)

LMPD ID
LMP010557
Gene ID
843077
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
lipoxygenase 6
Gene Symbol
AT1G67560
Synonyms
F12B7.11; F12B7_11
Alternate Names
lipoxygenase 6
Chromosome
1
EC Number
1.13.11.12

Proteins

lipoxygenase 6
Refseq ID NP_176923
Protein GI 15220475
UniProt ID Q9CAG3
mRNA ID NM_105423
Length 917
RefSeq Status REVIEWED
MFVASPVKTNFNGVSLVKSPAFSALSCRKQHRVPISRQVRAVISREEKAVDQEDGKKSTNKPLINSSQFPWQRSKYTGSKTVTAVVKIRKKIKEKLTERFEHQLELFMKAIGQGMLIQLVSEEIDPETGKGRKSLESPVMGLPKAVKDPRYLVFTADFTVPINFGKPGAILVTNLLSTEICLSEIIIEDSTDTILFPANTWIHSKNDNPQARIIFRSQPCLPSETPDGIKELREKDLVSVRGDGKGERKPHERIYDYDVYNDLGDPRKTERVRPVLGVPETPYPRRCRTGRPLVSKDPPCESRGKEKEEFYVPRDEVFEEIKRDTFRAGRFKALFHNLVPSIAAALSNLDIPFTCFSDIDNLYKSNIVLGHTEPKDTGLGGFIGGFMNGILNVTETLLKYDTPAVIKWDRFAWLRDNEFGRQALAGVNPVNIELLKELPIRSNLDPALYGPQESVLTEEIIAREVEHYGTTIEKALEEKRLFLVDYHDILLPFVEKINSIKEDPRKTYASRTIFFYSKNGALRPLAIELSLPPTAESENKFVYTHGHDATTHWIWKLAKAHVCSNDAGVHQLVNHWLRTHASMEPYIIATNRQLSTMHPVYKLLHPHMRYTLEINARARKSLINGGGIIESCFTPGKYAMELSSAAYKSMWRFDMEGLPADLVRRGMAEEDSSAECGVRLVIDDYPYAADGLLIWKAIKDLVESYVKHFYSDSKSITSDLELQAWWDEIKNKGHYDKKDEPWWPKLNTTQDLSQILTNMIWIASGQHAAINFGQYPFGGYVPNRPTLLRKLIPQETDPDYEMFMRNPQYSFLGSLPTQLQATKVMAVQETLSTHSPDEEYLIELREVQRHWFQDEQVVKYFNKFSEELVKIEKTINERNKDKKLKNRTGAGMPPYELLLPTSPHGVTGRGIPNSISI

Gene Information

Entrez Gene ID
843077
Gene Name
lipoxygenase 6
Gene Symbol
AT1G67560
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009507 IDA:TAIR C chloroplast
GO:0005886 IDA:TAIR C plasma membrane
GO:0005506 IEA:InterPro F iron ion binding
GO:0016165 IDA:UniProtKB F linoleate 13S-lipoxygenase activity
GO:0009695 IMP:TAIR P jasmonic acid biosynthetic process
GO:0034440 IDA:TAIR P lipid oxidation
GO:0031408 IEA:UniProtKB-UniPathway P oxylipin biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath00592 alpha-Linolenic acid metabolism
ath_M00113 Jasmonic acid biosynthesis
ath00591 Linoleic acid metabolism

REACTOME Pathway Links

REACTOME Pathway ID Description
6254372 Synthesis of 12-eicosatetraenoic acid derivatives

Domain Information

InterPro Annotations

Accession Description
IPR008976 Lipase/lipooxygenase, PLAT/LH2
IPR000907 Lipoxygenase
IPR020834 Lipoxygenase, conserved site
IPR013819 Lipoxygenase, C-terminal
IPR027433 Lipoxygenase, domain 3
IPR020833 Lipoxygenase, iron binding site
IPR001246 Lipoxygenase, plant
IPR001024 PLAT/LH2 domain

UniProt Annotations

Entry Information

Gene Name
lipoxygenase 6
Protein Entry
LOX6_ARATH
UniProt ID
Q9CAG3
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity Alpha-linolenate + O(2) = (9Z,11E,13S,15Z)-13- hydroperoxyoctadeca-9,11,15-trienoate.
Catalytic Activity Linoleate + O(2) = (9Z,11E,13S)-13- hydroperoxyoctadeca-9,11-dienoate.
Cofactor Name=Fe cation; Xref=ChEBI:CHEBI:24875; Evidence={ECO:0000255|PROSITE-ProRule:PRU00726}; Note=Binds 1 Fe cation per subunit. {ECO:0000255|PROSITE- ProRule:PRU00726};
Function Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure (By similarity). 13S-lipoxygenase that can use linolenic acid as substrates. {ECO:0000255|PROSITE- ProRule:PRU00726, ECO:0000269|PubMed:18949503}.
Pathway Lipid metabolism; oxylipin biosynthesis. {ECO:0000255|PROSITE-ProRule:PRU00726}.
Sequence Caution Sequence=BAD95111.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Similarity Belongs to the lipoxygenase family. {ECO:0000305}.
Similarity Contains 1 lipoxygenase domain. {ECO:0000255|PROSITE- ProRule:PRU00726}.
Similarity Contains 1 PLAT domain. {ECO:0000255|PROSITE- ProRule:PRU00152}.
Subcellular Location Plastid, chloroplast {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010557 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15220475 RefSeq NP_176923 917 lipoxygenase 6

Identical Sequences to LMP010557 proteins

Reference Database Accession Length Protein Name
GI:15220475 EMBL CAG38328.1 917 13-lipoxygenase [Arabidopsis thaliana]
GI:15220475 GenBank AAG52309.1 917 putative lipoxygenase [Arabidopsis thaliana]
GI:15220475 GenBank AAL91142.1 917 putative lipoxygenase [Arabidopsis thaliana]
GI:15220475 GenBank AAQ65169.1 917 At1g67560 [Arabidopsis thaliana]
GI:15220475 GenBank AEE34664.1 917 lipoxygenase 6 [Arabidopsis thaliana]
GI:15220475 SwissProt Q9CAG3.1 917 RecName: Full=Lipoxygenase 6, chloroplastic; Short=AtLOX6; Flags: Precursor [Arabidopsis thaliana]

Related Sequences to LMP010557 proteins

Reference Database Accession Length Protein Name
GI:15220475 GenBank EFH63389.1 917 lipoxygenase family protein [Arabidopsis lyrata subsp. lyrata]
GI:15220475 GenBank EOA33595.1 920 hypothetical protein CARUB_v10019745mg [Capsella rubella]
GI:15220475 RefSeq XP_002887130.1 917 lipoxygenase family protein [Arabidopsis lyrata subsp. lyrata]
GI:15220475 RefSeq XP_006300697.1 920 hypothetical protein CARUB_v10019745mg [Capsella rubella]
GI:15220475 RefSeq XP_010511701.1 919 PREDICTED: lipoxygenase 6, chloroplastic [Camelina sativa]
GI:15220475 RefSeq XP_010415331.1 919 PREDICTED: lipoxygenase 6, chloroplastic-like [Camelina sativa]