Gene/Proteome Database (LMPD)

LMPD ID
LMP010564
Gene ID
828484
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
long chain acyl-CoA synthetase 4
Gene Symbol
LACS4
Synonyms
long-chain acyl-CoA synthetase 4; T32A16.20; T32A16_20
Alternate Names
long chain acyl-CoA synthetase 4
Chromosome
4
EC Number
6.2.1.3

Proteins

long chain acyl-CoA synthetase 4
Refseq ID NP_194116
Protein GI 15236634
UniProt ID Q9T0A0
mRNA ID NM_118516
Length 666
RefSeq Status REVIEWED
MSQQKKYIFQVEEGKEGSDGRPSVGPVYRSIFAKDGFPDPIEGMDSCWDVFRMSVEKYPNNPMLGRREIVDGKPGKYVWQTYQEVYDIVMKLGNSLRSVGVKDEAKCGIYGANSPEWIISMEACNAHGLYCVPLYDTLGADAVEFIISHSEVSIVFVEEKKISELFKTCPNSTEYMKTVVSFGGVSREQKEEAETFGLVIYAWDEFLKLGEGKQYDLPIKKKSDICTIMYTSGTTGDPKGVMISNESIVTLIAGVIRLLKSANEALTVKDVYLSYLPLAHIFDRVIEECFIQHGAAIGFWRGDVKLLIEDLAELKPTIFCAVPRVLDRVYSGLQKKLSDGGFLKKFIFDSAFSYKFGYMKKGQSHVEASPLFDKLVFSKVKQGLGGNVRIILSGAAPLASHVESFLRVVACCHVLQGYGLTESCAGTFVSLPDELGMLGTVGPPVPNVDIRLESVPEMEYDALASTARGEICIRGKTLFSGYYKREDLTKEVLIDGWLHTGDVGEWQPDGSMKIIDRKKNIFKLSQGEYVAVENIENIYGEVQAVDSVWVYGNSFESFLIAIANPNQHILERWAAENGVSGDYDALCQNEKAKEFILGELVKMAKEKKMKGFEIIKAIHLDPVPFDMERDLLTPTFKKKRPQLLKYYQSVIDEMYKTINAKFASRG

Gene Information

Entrez Gene ID
828484
Gene Name
long chain acyl-CoA synthetase 4
Gene Symbol
LACS4
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IDA:TAIR C Golgi apparatus
GO:0005886 IDA:TAIR C plasma membrane
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0004467 IDA:UniProtKB F long-chain fatty acid-CoA ligase activity
GO:0006631 TAS:UniProtKB P fatty acid metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ath_M00086 beta-Oxidation, acyl-CoA synthesis
ath00061 Fatty acid biosynthesis
ath00071 Fatty acid degradation
ath04146 Peroxisome

Domain Information

InterPro Annotations

Accession Description
IPR020845 AMP-binding, conserved site
IPR000873 AMP-dependent synthetase/ligase

UniProt Annotations

Entry Information

Gene Name
long chain acyl-CoA synthetase 4
Protein Entry
LACS4_ARATH
UniProt ID
Q9T0A0
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA. {ECO:0000269|PubMed:12177484}.
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
Function Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate.
Pathway Lipid metabolism; fatty acid metabolism.
Similarity Belongs to the ATP-dependent AMP-binding enzyme family. {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010564 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15236634 RefSeq NP_194116 666 long chain acyl-CoA synthetase 4

Identical Sequences to LMP010564 proteins

Reference Database Accession Length Protein Name
GI:15236634 EMBL CBF64970.1 666 unnamed protein product [Arabidopsis thaliana]
GI:15236634 EMBL CBU89841.1 666 unnamed protein product [Arabidopsis thaliana]
GI:15236634 GenBank ABJ40797.1 666 Sequence 128 from patent US 7105722
GI:15236634 GenBank AEE84812.1 666 long chain acyl-CoA synthetase 4 [Arabidopsis thaliana]
GI:15236634 GenBank AGX56870.1 666 Sequence 14059 from patent US 8541208
GI:15236634 SwissProt Q9T0A0.1 666 RecName: Full=Long chain acyl-CoA synthetase 4 [Arabidopsis thaliana]

Related Sequences to LMP010564 proteins

Reference Database Accession Length Protein Name
GI:15236634 GenBank ABJ40755.1 666 Sequence 12 from patent US 7105722
GI:15236634 GenBank ACC91252.1 666 long-chain-fatty-acid-CoA ligase [Arabidopsis halleri]
GI:15236634 GenBank EFH43946.1 666 long-chain-fatty-acid--CoA ligase [Arabidopsis lyrata subsp. lyrata]
GI:15236634 RefSeq XP_002867687.1 666 long-chain-fatty-acid--CoA ligase [Arabidopsis lyrata subsp. lyrata]
GI:15236634 RefSeq XP_010439129.1 666 PREDICTED: long chain acyl-CoA synthetase 4 [Camelina sativa]
GI:15236634 RefSeq XP_010448651.1 666 PREDICTED: long chain acyl-CoA synthetase 4 [Camelina sativa]