Gene/Proteome Database (LMPD)

LMPD ID
LMP010565
Gene ID
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
long-chain acyl-CoA synthetase
Gene Symbol
Synonyms
T22B4.10; T22B4_10
Alternate Names
long-chain acyl-CoA synthetase
Chromosome
4
EC Number
6.2.1.3

Proteins

long-chain acyl-CoA synthetase
Refseq ID NP_192841
Protein GI 15237023
UniProt ID Q9T009
mRNA ID NM_117173
Length 666
RefSeq Status REVIEWED
MTSQKRFIFEVEAAKEATDGNPSVGPVYRSTFAQNGFPNPIDGIQSCWDIFRTAVEKYPNNRMLGRREISNGKAGKYVWKTYKEVYDIVIKLGNSLRSCGIKEGEKCGIYGINCCEWIISMEACNAHGLYCVPLYDTLGAGAVEFIISHAEVSIAFVEEKKIPELFKTCPNSTKYMKTVVSFGGVKPEQKEEAEKLGLVIHSWDEFLKLGEGKQYELPIKKPSDICTIMYTSGTTGDPKGVMISNESIVTITTGVMHFLGNVNASLSEKDVYISYLPLAHVFDRAIEECIIQVGGSIGFWRGDVKLLIEDLGELKPSIFCAVPRVLDRVYTGLQQKLSGGGFFKKKVFDVAFSYKFGNMKKGQSHVAASPFCDKLVFNKVKQGLGGNVRIILSGAAPLASHIESFLRVVACCNVLQGYGLTESCAGTFATFPDELDMLGTVGPPVPNVDIRLESVPEMNYDALGSTPRGEICIRGKTLFSGYYKREDLTKEVFIDGWLHTGDVGEWQPNGSMKIIDRKKNIFKLAQGEYVAVENLENVYSQVEVIESIWVYGNSFESFLVAIANPAQQTLERWAVENGVNGDFNSICQNAKAKAFILGELVKTAKENKLKGFEIIKDVHLEPVAFDMERDLLTPTYKKKRPQLLKYYQNVIHEMYKTTKESLASGQ

Gene Information

Entrez Gene ID
Gene Name
long-chain acyl-CoA synthetase
Gene Symbol
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0004467 IDA:UniProtKB F long-chain fatty acid-CoA ligase activity
GO:0006631 TAS:UniProtKB P fatty acid metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ath00061 Fatty acid biosynthesis
ath00071 Fatty acid degradation
ath04146 Peroxisome
ath_M00086 beta-Oxidation, acyl-CoA synthesis

Domain Information

InterPro Annotations

Accession Description
IPR020845 AMP-binding, conserved site
IPR000873 AMP-dependent synthetase/ligase

UniProt Annotations

Entry Information

Gene Name
long-chain acyl-CoA synthetase
Protein Entry
LACS5_ARATH
UniProt ID
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA. {ECO:0000269|PubMed:12177484}.
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
Function Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate.
Pathway Lipid metabolism; fatty acid metabolism.
Sequence Caution Sequence=AAC33962.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the ATP-dependent AMP-binding enzyme family. {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010565 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15237023 RefSeq NP_192841 666 long-chain acyl-CoA synthetase

Identical Sequences to LMP010565 proteins

Reference Database Accession Length Protein Name
GI:15237023 EMBL CBF64969.1 666 unnamed protein product [Arabidopsis thaliana]
GI:15237023 EMBL CBU89840.1 666 unnamed protein product [Arabidopsis thaliana]
GI:15237023 GenBank ACI49793.1 666 At4g11030 [Arabidopsis thaliana]
GI:15237023 GenBank AEE82963.1 666 long-chain acyl-CoA synthetase [Arabidopsis thaliana]
GI:15237023 GenBank AGX56869.1 666 Sequence 14057 from patent US 8541208
GI:15237023 SwissProt Q9T009.1 666 RecName: Full=Long chain acyl-CoA synthetase 5 [Arabidopsis thaliana]

Related Sequences to LMP010565 proteins

Reference Database Accession Length Protein Name
GI:15237023 GenBank AAM28872.1 666 long chain acyl-CoA synthetase 5 [Arabidopsis thaliana]
GI:15237023 GenBank ABJ40756.1 658 Sequence 13 from patent US 7105722
GI:15237023 GenBank ABJ40798.1 666 Sequence 129 from patent US 7105722
GI:15237023 GenBank EFH48802.1 666 hypothetical protein ARALYDRAFT_352166 [Arabidopsis lyrata subsp. lyrata]
GI:15237023 RefSeq XP_002872543.1 666 hypothetical protein ARALYDRAFT_352166 [Arabidopsis lyrata subsp. lyrata]
GI:15237023 RefSeq XP_010435688.1 666 PREDICTED: LOW QUALITY PROTEIN: long chain acyl-CoA synthetase 5-like [Camelina sativa]