Gene/Proteome Database (LMPD)

LMPD ID
LMP010568
Gene ID
814974
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
long chain acyl-CoA synthetase 8
Gene Symbol
LACS8
Synonyms
long-chain acyl-CoA synthetase 8; T23O15.3; T23O15_3
Alternate Names
long chain acyl-CoA synthetase 8
Chromosome
2
EC Number
6.2.1.3

Proteins

long chain acyl-CoA synthetase 8
Refseq ID NP_178516
Protein GI 15228136
UniProt ID Q9SJD4
mRNA ID NM_126468
Length 720
RefSeq Status REVIEWED
MEDSGVNPMDSPSKGSDFGVYGIIGGGIVALLVPVLLSVVLNGTKKGKKRGVPIKVGGEEGYTMRHARAPELVDVPWEGAATMPALFEQSCKKYSKDRLLGTREFIDKEFITASDGRKFEKLHLGEYKWQSYGEVFERVCNFASGLVNVGHNVDDRVAIFSDTRAEWFIAFQGCFRQSITVVTIYASLGEEALIYSLNETRVSTLICDSKQLKKLSAIQSSLKTVKNIIYIEEDGVDVASSDVNSMGDITVSSISEVEKLGQKNAVQPILPSKNGVAVIMFTSGSTGLPKGVMITHGNLVATAAGVMKVVPKLDKNDTYIAYLPLAHVFELEAEIVVFTSGSAIGYGSAMTLTDTSNKVKKGTKGDVSALKPTIMTAVPAILDRVREGVLKKVEEKGGMAKTLFDFAYKRRLAAVDGSWFGAWGLEKMLWDALVFKKIRAVLGGHIRFMLVGGAPLSPDSQRFINICMGSPIGQGYGLTETCAGATFSEWDDPAVGRVGPPLPCGYVKLVSWEEGGYRISDKPMPRGEIVVGGNSVTAGYFNNQEKTDEVYKVDEKGTRWFYTGDIGRFHPDGCLEVIDRKKDIVKLQHGEYVSLGKVEAALGSSNYVDNIMVHADPINSYCVALVVPSRGALEKWAEEAGVKHSEFAELCEKGEAVKEVQQSLTKAGKAAKLEKFELPAKIKLLSEPWTPESGLVTAALKIKREQIKSKFKDELSKLYA
long chain acyl-CoA synthetase 8
Refseq ID NP_849934
Protein GI 30678112
UniProt ID Q9SJD4
mRNA ID NM_179603
Length 720
RefSeq Status REVIEWED
Protein sequence is identical to GI:15228136 (mRNA isoform)

Gene Information

Entrez Gene ID
814974
Gene Name
long chain acyl-CoA synthetase 8
Gene Symbol
LACS8
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009941 IDA:TAIR C chloroplast envelope
GO:0005783 IDA:TAIR C endoplasmic reticulum
GO:0005794 IDA:TAIR C Golgi apparatus
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0004467 IDA:UniProtKB F long-chain fatty acid-CoA ligase activity
GO:0006631 TAS:UniProtKB P fatty acid metabolic process
GO:0001676 IDA:GOC P long-chain fatty acid metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ath_M00086 beta-Oxidation, acyl-CoA synthesis
ath00061 Fatty acid biosynthesis
ath00071 Fatty acid degradation
ath04146 Peroxisome

Domain Information

InterPro Annotations

Accession Description
IPR020845 AMP-binding, conserved site
IPR000873 AMP-dependent synthetase/ligase

UniProt Annotations

Entry Information

Gene Name
long chain acyl-CoA synthetase 8
Protein Entry
LACS8_ARATH
UniProt ID
Q9SJD4
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA. {ECO:0000269|PubMed:12177484}.
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
Function Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate.
Pathway Lipid metabolism; fatty acid metabolism.
Similarity Belongs to the ATP-dependent AMP-binding enzyme family. {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010568 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15228136 RefSeq NP_178516 720 long chain acyl-CoA synthetase 8

Identical Sequences to LMP010568 proteins

Reference Database Accession Length Protein Name
GI:15228136 GenBank AAM28875.1 720 long chain acyl-CoA synthetase 8 [Arabidopsis thaliana]
GI:15228136 GenBank AAN72299.1 720 At2g04350/T23O15.3 [Arabidopsis thaliana]
GI:15228136 GenBank AEC05822.1 720 long chain acyl-CoA synthetase 8 [Arabidopsis thaliana]
GI:15228136 GenBank AEC05823.1 720 long chain acyl-CoA synthetase 8 [Arabidopsis thaliana]
GI:15228136 RefSeq NP_849934.1 720 long chain acyl-CoA synthetase 8 [Arabidopsis thaliana]
GI:15228136 SwissProt Q9SJD4.1 720 RecName: Full=Long chain acyl-CoA synthetase 8 [Arabidopsis thaliana]

Related Sequences to LMP010568 proteins

Reference Database Accession Length Protein Name
GI:15228136 EMBL CBF65081.1 720 unnamed protein product [Arabidopsis thaliana]
GI:15228136 EMBL CBU89952.1 720 unnamed protein product [Arabidopsis thaliana]
GI:15228136 GenBank AAK96568.1 720 T23O15.3/T23O15.3 [Arabidopsis thaliana]
GI:15228136 GenBank ABJ40764.1 720 Sequence 21 from patent US 7105722
GI:15228136 GenBank ACX05308.1 720 Sequence 28446 from patent US 7569389
GI:15228136 GenBank AGX56981.1 720 Sequence 14281 from patent US 8541208