Gene/Proteome Database (LMPD)

LMPD ID
LMP010569
Gene ID
844094
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
long chain acyl-CoA synthetase 9
Gene Symbol
LACS9
Synonyms
long chain acyl-CoA synthetase 9; T5M16.18; T5M16_18
Alternate Names
long chain acyl-CoA synthetase 9
Chromosome
1
EC Number
6.2.1.3
Summary
Encodes major plastidic long chain acyl-CoA synthetase with a slight substrate preference of oleic acid over any of the other fatty acids.
Orthologs
View orthologs and multiple alignments for LACS9

Proteins

long chain acyl-CoA synthetase 9
Refseq ID NP_177882
Protein GI 15224012
UniProt ID Q9CAP8
mRNA ID NM_106407
Length 691
RefSeq Status REVIEWED
MIPYAAGVIVPLALTFLVQKSKKEKKRGVVVDVGGEPGYAIRNHRFTEPVSSHWEHISTLPELFEISCNAHSDRVFLGTRKLISREIETSEDGKTFEKLHLGDYEWLTFGKTLEAVCDFASGLVQIGHKTEERVAIFADTREEWFISLQGCFRRNVTVVTIYSSLGEEALCHSLNETEVTTVICGSKELKKLMDISQQLETVKRVICMDDEFPSDVNSNWMATSFTDVQKLGRENPVDPNFPLSADVAVIMYTSGSTGLPKGVMMTHGNVLATVSAVMTIVPDLGKRDIYMAYLPLAHILELAAESVMATIGSAIGYGSPLTLTDTSNKIKKGTKGDVTALKPTIMTAVPAILDRVRDGVRKKVDAKGGLSKKLFDFAYARRLSAINGSWFGAWGLEKLLWDVLVFRKIRAVLGGQIRYLLSGGAPLSGDTQRFINICVGAPIGQGYGLTETCAGGTFSEFEDTSVGRVGAPLPCSFVKLVDWAEGGYLTSDKPMPRGEIVIGGSNITLGYFKNEEKTKEVYKVDEKGMRWFYTGDIGRFHPDGCLEIIDRKKDIVKLQHGEYVSLGKVEAALSISPYVENIMVHADSFYSYCVALVVASQHTVEGWASKQGIDFANFEELCTKEQAVKEVYASLVKAAKQSRLEKFEIPAKIKLLASPWTPESGLVTAALKLKRDVIRREFSEDLTKLYA

Gene Information

Entrez Gene ID
844094
Gene Name
long chain acyl-CoA synthetase 9
Gene Symbol
LACS9
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009507 IDA:TAIR C chloroplast
GO:0009941 IDA:TAIR C chloroplast envelope
GO:0016020 IDA:TAIR C membrane
GO:0009536 IDA:TAIR C plastid
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0004467 IDA:TAIR F long-chain fatty acid-CoA ligase activity
GO:0006631 TAS:TAIR P fatty acid metabolic process
GO:0001676 IDA:GOC P long-chain fatty acid metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ath00061 Fatty acid biosynthesis
ath00071 Fatty acid degradation
ath04146 Peroxisome
ath_M00086 beta-Oxidation, acyl-CoA synthesis

Domain Information

InterPro Annotations

Accession Description
IPR020845 AMP-binding, conserved site
IPR000873 AMP-dependent synthetase/ligase

UniProt Annotations

Entry Information

Gene Name
long chain acyl-CoA synthetase 9
Protein Entry
LACS9_ARATH
UniProt ID
Q9CAP8
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA. {ECO:0000269|PubMed:12177484}.
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
Disruption Phenotype Reduced amount long-chain fatty acid (LCFA). {ECO:0000269|PubMed:12177483}.
Function Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate. {ECO:0000269|PubMed:12177483}.
Pathway Lipid metabolism; fatty acid metabolism.
Similarity Belongs to the ATP-dependent AMP-binding enzyme family. {ECO:0000305}.
Subcellular Location Plastid, chloroplast envelope {ECO:0000269|PubMed:12177483}.
Tissue Specificity Highly expressed in developing seeds and young rosette leaves. {ECO:0000269|PubMed:12177483}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010569 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15224012 RefSeq NP_177882 691 long chain acyl-CoA synthetase 9

Identical Sequences to LMP010569 proteins

Reference Database Accession Length Protein Name
GI:15224012 EMBL CBF64936.1 691 unnamed protein product [Arabidopsis thaliana]
GI:15224012 EMBL CBU89807.1 691 unnamed protein product [Arabidopsis thaliana]
GI:15224012 GenBank ABJ40801.1 691 Sequence 132 from patent US 7105722
GI:15224012 GenBank AEE35996.1 691 long chain acyl-CoA synthetase 9 [Arabidopsis thaliana]
GI:15224012 GenBank AGX56836.1 691 Sequence 13991 from patent US 8541208
GI:15224012 SwissProt Q9CAP8.1 691 RecName: Full=Long chain acyl-CoA synthetase 9, chloroplastic [Arabidopsis thaliana]

Related Sequences to LMP010569 proteins

Reference Database Accession Length Protein Name
GI:15224012 GenBank ABJ40765.1 691 Sequence 22 from patent US 7105722
GI:15224012 GenBank EFH65408.1 691 long chain acyl-CoA synthetase 9 [Arabidopsis lyrata subsp. lyrata]
GI:15224012 RefSeq XP_002889149.1 691 long chain acyl-CoA synthetase 9 [Arabidopsis lyrata subsp. lyrata]
GI:15224012 RefSeq XP_010416710.1 691 PREDICTED: long chain acyl-CoA synthetase 9, chloroplastic [Camelina sativa]
GI:15224012 RefSeq XP_010416711.1 691 PREDICTED: long chain acyl-CoA synthetase 9, chloroplastic [Camelina sativa]
GI:15224012 RefSeq XP_010471955.1 691 PREDICTED: long chain acyl-CoA synthetase 9, chloroplastic-like [Camelina sativa]